Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laurent Coussy"'
Autor:
Frédérique Barbosa, Frédéric Revah, Dragos Horvath, Laurent Coussy, Rafael Gozalbes, Marie-France Paugam, Eric Nicolai, Catherine Rolland
Publikováno v:
Journal of Medicinal Chemistry. 48:6563-6574
A QSAR model accounting for "average" G-protein-coupled receptor (GPCR) binding was built from a large set of experimental standardized binding data (1939 compounds systematically tested over 40 different GPCRs) and applied to the design of a library
Autor:
Catherine Rolland, Dragos Horvath, Laurent Coussy, Rafael Gozalbes, Frédéric Revah, Nicolas Froloff, Marie-France Paugam, Eric Nicolaï, Frédérique Barbosa, Boryeu Mao
Publikováno v:
QSAR & Combinatorial Science. 24:508-516
An innovative approach has been developed in order to construct new GPCR focused libraries. Experimental binding data generated in house from 1939 diverse drug and drug-like compounds on 40 GPCR targets were used to develop and validate a "global GPC
Autor:
Rafael Gozalbes, Catherine Rolland, Eric Nicolaï, Marie-France Paugam, Laurent Coussy, Dragos Horvath, Frédérique Barbosa, Boryeu Mao, Frédéric Revah, Nicolas Froloff
Publikováno v:
QSAR & Combinatorial Science; Jun2005, Vol. 24 Issue 4, p508-516, 9p