Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Laurent Collard"'
Autor:
Doriane Muller, Benjamin Elias, Laurent Collard, Christophe Pels, Marie-Jeanne Holveck, Caroline M Nieberding
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225003 (2019)
Polyphenism is a type of phenotypic plasticity supposedly adaptive to drastic and recurrent changes in the environment such as seasonal alternation in temperate and tropical regions. The butterfly Bicyclus anynana shows polyphenism with well-describe
Externí odkaz:
https://doaj.org/article/4be1dbf0722144e585ace31cd7849770
Autor:
Xavier Buol, Koen Robeyns, Camila Caro Garrido, Nikolay Tumanov, Laurent Collard, Johan Wouters, Tom Leyssens
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 653 (2020)
In this work, we are the first to identify thirteen cocrystals of Nefiracetam, a poor water-soluble nootropic compound. Three of which were obtained with the biocompatible cocrystallization agents citric acid, oxalic acid, and zinc chloride. These la
Externí odkaz:
https://doaj.org/article/aa29a5f9ed88451f91e54de5f56b9475
Publikováno v:
Chemical Communications. 58:8560-8563
We present a thought-provoking development in chiral resolution. Using a resolving agent of a given handedness, L-proline, we show that both R- and S-enantiomers of mandelic acid can be resolved from a racemic mixture simply by varying the stoichiome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094640c3e45a15d32e656894827b559f
https://doi.org/10.1039/d2cc02942a
https://doi.org/10.1039/d2cc02942a
Autor:
Guillaume Berionni, Damien Mahaut, Lei Hu, Nikolay Tumanov, Laurent Collard, Raphaël Robiette, Johan Wouters
Publikováno v:
Dalton Transactions, Vol. 50, no.14, p. 4772-4777 (2021)
ortho-Substituted and unsymmetrical 9-phospha-triptycenes were synthesizedviatwo synthetic approaches involving densely functionalizedortho-halogenated triarylmethane or phosphine precursors.ortho-Substituents imposed a considerable steric shielding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46b846752479be070c0bbc277d3264a
https://doi.org/10.1039/d1dt00816a
https://doi.org/10.1039/d1dt00816a
Autor:
Nikolay Tumanov, Johan Wouters, Xavier Buol, Tom Leyssens, Laurent Collard, Camila Caro Garrido, Koen Robeyns
Publikováno v:
Crystal Growth & Design, Vol. 20, no.12, p. 7979-7988 (2020)
In this paper, we identified a cocrystal conglomerate of mandelic acid using a drug compound as a coformer. We then developed a chiral resolution process based on preferential cocrystallization. Several versions of such a process were explored and op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8430a31fa3f46deef47832a271c3ed22
https://doi.org/10.1021/acs.cgd.0c01236
https://doi.org/10.1021/acs.cgd.0c01236
Autor:
Joop H. ter Horst, Chloé Matheys, Tom Leyssens, Laurent Collard, Maxime D. Charpentier, Fuli Zhou, Oleksii Shemchuk
We tap into an unexplored area of preferential crystallization, being the first to develop simultaneous chiral resolution of two racemic compounds by preferential cocrystallization.We highlight how the two racemic compounds RS-mandelic acid (MAN) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed7ecc92ee8d8a4d30d0bd9164e72d8
https://strathprints.strath.ac.uk/78134/1/Zhou_etal_ACIE_2021_Simultaneous_chiral_resolution_of_two_racemic_compounds.pdf
https://strathprints.strath.ac.uk/78134/1/Zhou_etal_ACIE_2021_Simultaneous_chiral_resolution_of_two_racemic_compounds.pdf
Publikováno v:
Organic Process Research & Development, Vol. 25, no.4, p. 884-891 (2021)
We recently introduced a thermodynamically based deracemization process, co-crystallization-induced spontaneous deracemization (CoISD). Following the successful development of the CoISD process, we aimed at improving both yield and deracemization and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c70a923e09d3e19700469460a47f31
https://hdl.handle.net/2078.1/246592
https://hdl.handle.net/2078.1/246592
Autor:
Olivier Riant, Koen Robeyns, josephine demeester, Michael Guillot, sarah huynen, Tom Leyssens, Laurent Collard
Processes leading to enantiopure compounds are of utmost importance, in particular for the pharmaceutical industry. Starting from a racemic mixture, Crystallization Induced Diastereomeric Transformation allows for a theoretical 100% transformation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cd2a1ee3ef357feec510d3579c4a16
https://doi.org/10.26434/chemrxiv.11861274.v1
https://doi.org/10.26434/chemrxiv.11861274.v1
Autor:
Denise M. Croker, Ricky Payen, Tom Leyssens, Laurent Collard, J.B. de Maere d’Aertrycke, Koen Robeyns
Publikováno v:
Crystal Growth & Design, Vol. 20, no.3, p. 2035-2043 (2020)
peer-reviewed Caffeine and maleic acid can form various cocrystal forms, which is a potential route to avoiding hydration issues of caffeine. This particular system was intensively studied as it not only shows cocrystal polymorphism but also stoichio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d6f754fe5551307604eedffc9d4fe7
https://hdl.handle.net/2078.1/228284
https://hdl.handle.net/2078.1/228284
Autor:
Michael Guillot, Koen Robeyns, Tom Leyssens, Laurent Collard, sarah huynen, Olivier Riant, Joséphine de Meester
Publikováno v:
Angewandte Chemie International Edition, (2020)
Processes leading to enantiomerically pure compounds are of utmost importance, in particular for the pharmaceutical industry. Starting from a racemic mixture, crystallization-induced diastereomeric transformation allows in theory for 100 % transforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a3e21ff1b0d699c7d233856109b49a
https://hdl.handle.net/2078.1/229576
https://hdl.handle.net/2078.1/229576