Is adult cardiac regeneration absent in Xenopus laevis yet present in Xenopus tropicalis?

Autor: Lindsey Marshall, Fabrice Girardot, Barbara A. Demeneix, Laurent Coen

Publikováno v: Cell & Bioscience, Vol 8, Iss 1, Pp 1-4 (2018)

Abstract We recently used an endoscopy-based resection method to explore the consequences of cardiac injury in adult Xenopus laevis, obtaining the result that the adult Xenopus heart is unable to regenerate. At 11 months post-amputation, cellular and

Externí odkaz: https://doaj.org/article/08ca55e395954953a2ba8de592be49e0

On the origin and evolutionary history of NANOG.

Autor: Pierluigi Scerbo, Gabriel V Markov, Céline Vivien, Laurent Kodjabachian, Barbara Demeneix, Laurent Coen, Fabrice Girardot

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85104 (2014)

Though pluripotency is well characterized in mammals, many questions remain to be resolved regarding its evolutionary history. A necessary prerequisite for addressing this issue is to determine the phylogenetic distributions and orthology relationshi

Externí odkaz: https://doaj.org/article/ee19a19bce534ebab9e9164a2ac83cd9

Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws.

Autor: Maxence Vieux-Rochas, Laurent Coen, Takahiro Sato, Yukiko Kurihara, Yorick Gitton, Ottavia Barbieri, Karine Le Blay, Giorgio Merlo, Marc Ekker, Hiroki Kurihara, Philippe Janvier, Giovanni Levi

Publikováno v: PLoS ONE, Vol 2, Iss 6, p e510 (2007)

Intake of retinoic acid (RA) or of its precursor, vitamin A, during early pregnancy is associated with increased incidence of craniofacial lesions. The origin of these teratogenic effects remains enigmatic as in cranial neural crest cells (CNCCs), wh

Externí odkaz: https://doaj.org/article/be60c8565f364be0ab0f11ec47ed7629

Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability

Autor: Fabrice Girardot, Céline Vivien, Louise Péricard, Karima Palmier, Pierluigi Scerbo, Laurent Coen, Lindsey Marshall, Barbara A. Demeneix

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (9), pp.3614-3623. ⟨10.1073/pnas.1803794116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (9), pp.3614-3623. ⟨10.1073/pnas.1803794116⟩

International audience; Despite therapeutic advances, heart failure is the major cause of morbidity and mortality worldwide, but why cardiac regenerative capacity is lost in adult humans remains an enigma. Cardiac regenerative capacity widely varies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e0c25f3f86c62836be6e4bae6285ca
https://hal.archives-ouvertes.fr/hal-03319960

In Vivo Transfection of Naked DNA into

Autor: Lindsey, Marshall, Fabrice, Girardot, Barbara A, Demeneix, Laurent, Coen

Publikováno v: Cold Spring Harbor protocols. 2017(11)

In vivo gene transfer systems are important to study foreign gene expression and promoter regulation in an organism, with the benefit of exploring this in an integrated environment. Direct injection of plasmids encoding exogenous promoters and genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::974e7b3c53a4e9459669cae3a9b07c97
https://pubmed.ncbi.nlm.nih.gov/29093206