Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Laurent Calvier"'
Autor:
Laurent Calvier, Anna Alexander, Austin T. Marckx, Maria Z. Kounnas, Murat Durakoglugil, Joachim Herz
Publikováno v:
Cells, Vol 13, Iss 7, p 583 (2024)
Reelin, a large extracellular glycoprotein, plays critical roles in neuronal development and synaptic plasticity in the central nervous system (CNS). Recent studies have revealed non-neuronal functions of plasma Reelin in inflammation by promoting en
Externí odkaz:
https://doaj.org/article/c3b91ad378ab4092bc6071e59599fc88
Publikováno v:
Immuno, Vol 2, Iss 3, Pp 506-511 (2022)
Under pathological conditions such as multiple sclerosis (MS), leukocytes infiltrate the central nervous system where they, in concert with activated microglia, promote inflammatory demyelination resulting in a broad spectrum of symptoms, including p
Externí odkaz:
https://doaj.org/article/5b6848f445cb44ebb90e752cd7cbe869
Autor:
Laurent Calvier, Aleksandra Drelich, Jason Hsu, Chien-Te Tseng, Yair Mina, Avindra Nath, Maria Z. Kounnas, Joachim Herz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Thromboembolic complications and excessive inflammation are frequent in severe COVID-19, potentially leading to long COVID. In non-COVID studies, we and others demonstrated that circulating Reelin promotes leukocyte infiltration and thrombosis. Thus,
Externí odkaz:
https://doaj.org/article/437d39fa6fcf4334a622e5ff9313463a
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112669- (2023)
Summary: Reelin was originally identified as a regulator of neuronal migration and synaptic function, but its non-neuronal functions have received far less attention. Reelin participates in organ development and physiological functions in various tis
Externí odkaz:
https://doaj.org/article/908a047a5f464a6fa89de2b1929dfc76
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/38563663e67b40e5b5f10433e0ce9995
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background It has been proposed that peroxisome proliferator-activated receptor-γ (PPARγ) agonists might reduce renal fibrosis, however, several studies had contradictory results. Moreover, the possible interaction of TGF-β1, PPARγ, and
Externí odkaz:
https://doaj.org/article/22d1ee326b734803b4f161f3ae4700dc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10431 (2021)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a type II nuclear receptor, initially recognized in adipose tissue for its role in fatty acid storage and glucose metabolism. It promotes lipid uptake and adipogenesis by increasing insulin
Externí odkaz:
https://doaj.org/article/600339ed309a44e9b79d52f2b8fbd480
Autor:
Ernesto Martinez-Martinez, Jaime Ibarrola, Laurent Calvier, Amaya Fernandez-Celis, Celine Leroy, Victoria Cachofeiro, Patrick Rossignol, Natalia Lopez-Andres
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166272 (2016)
BACKGROUND:Galectin-3 (Gal-3), a β-galactoside-binding lectin, is increased in kidney injury and its pharmacological blockade reduces renal damage in acute kidney injury, hyperaldosteronism or hypertensive nephropathy. We herein investigated the eff
Externí odkaz:
https://doaj.org/article/a2d97ddc71d84179aab5b033e1b5ca88
Publikováno v:
JACC: Basic to Translational Science. 7:164-180
The low-density lipoprotein receptor (LDLR) gene family includes LDLR, very LDLR, and LDL receptor-related proteins (LRPs) such as LRP1, LRP1b (aka LRP-DIT), LRP2 (aka megalin), LRP4, and LRP5/6, and LRP8 (aka ApoER2). LDLR family members constitute
Autor:
Philippe Chouvarine, Ekaterina Legchenko, Laurent Calvier, Georg Hansmann, Miklos Mozes, Gábor Kökény
Publikováno v:
Current Opinion in Nephrology and Hypertension. 29:171-179
Purpose of review Pulmonary arterial hypertension (PAH) is characterized by pulmonary arterial endothelial cell (PAEC) dysfunction and apoptosis, pulmonary arterial smooth muscle cell (PASMC) proliferation, inflammation, vasoconstriction, and metabol