Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laurent Azema"'
Autor:
Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100172- (2023)
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotr
Externí odkaz:
https://doaj.org/article/76fd39d35eed4b10bc8fe7a5d38243bc
Autor:
Laurent Azema, Emmanuel Tetaud, Dominique Cottem, Michèle Willson, Frederik Opperdoes, Isabelle Alric, Jacques Périé, Michael P. Barrett, Frédéric Bringaud, Casimir Blonski, Samantha Claustre, Théo Baltz
Publikováno v:
Biochemical Pharmacology. 67:459-467
Glucose metabolism is essential for survival of bloodstream form Trypanosoma brucei subspecies which cause human African trypanosomiasis (sleeping sickness). Hexose analogues may represent good compounds to inhibit glucose metabolism in these cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e3bb5477cb01b2aeb05fc8a9b33c18
https://doi.org/10.1016/j.bcp.2003.09.005
https://doi.org/10.1016/j.bcp.2003.09.005
Publikováno v:
Analytical Biochemistry. 318:142-145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3401b5f17689c5e8a5735eff33bd31f8
https://doi.org/10.1016/s0003-2697(03)00165-9
https://doi.org/10.1016/s0003-2697(03)00165-9
Autor:
Frédéric Bringaud, Laurent Azema, Rudi Baron, Michele Willson, Samantha Claustre, Jacques Périé
Publikováno v:
ChemInform. 30
1-Amino-2,5-anhydro-1-deoxy- d -mannitol and a series of arylamino derivatives were prepared by nitrous acid deamination of 2-amino-2-deoxy- d -glucose and subsequent reductive amination of the resulting 2,5-anhydro- d -mannose. Some of these compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::440eec56462939abdcd5f7f97329515b
https://doi.org/10.1002/chin.199945240
https://doi.org/10.1002/chin.199945240
Publikováno v:
Bioorganicmedicinal chemistry. 8(4)
Various D-fructose analogues modified at C-1 or C-6 positions were synthesized from D-glucose by taking advantage of the Amadori rearrangement or using the aldol condensation between dihydroxyacetone phosphate and appropriate aldehyde catalyzed by fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cafbb706222ee18868be304125738da
https://pubmed.ncbi.nlm.nih.gov/10819160
https://pubmed.ncbi.nlm.nih.gov/10819160
An easy stereospecific synthesis of 1-amino-2,5-anhydro-1-deoxy-D-mannitol and arylamino derivatives
Autor:
Jacques Périé, Michele Willson, Laurent Azema, Samantha Claustre, Frédéric Bringaud, Rudi Baron
Publikováno v:
Carbohydrate research. 315(3-4)
1-Amino-2,5-anhydro-1-deoxy- d -mannitol and a series of arylamino derivatives were prepared by nitrous acid deamination of 2-amino-2-deoxy- d -glucose and subsequent reductive amination of the resulting 2,5-anhydro- d -mannose. Some of these compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377b43c55c1770e7445d588e0e1ffc6d
https://pubmed.ncbi.nlm.nih.gov/10399304
https://pubmed.ncbi.nlm.nih.gov/10399304
Autor:
David Kryza, Frédéric Debordeaux, Laurent Azéma, Aref Hassan, Olivier Paurelle, Jürgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier, Jean Jacques Toulmé
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149387 (2016)
The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marker of malignant tumors, i
Externí odkaz:
https://doaj.org/article/1f5b26f287a94237928754a47e94864f