Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Laurent Azéma"'
1
Akademický článek
Aptamer-based nanotrains and nanoflowers as quinine delivery systems
Autor: Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Publikováno v: International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100172- (2023)
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotr
Externí odkaz: https://doaj.org/article/76fd39d35eed4b10bc8fe7a5d38243bc
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2
Akademický článek
Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas.
Autor: David Kryza, Frédéric Debordeaux, Laurent Azéma, Aref Hassan, Olivier Paurelle, Jürgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier, Jean Jacques Toulmé
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149387 (2016)
The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marker of malignant tumors, i
Externí odkaz: https://doaj.org/article/1f5b26f287a94237928754a47e94864f
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3
Aptamer-based nanotrains and nanoflowers as quinine delivery systems
Autor: Mengyuan Cao, Anthony Vial, Laetitia Minder, Aurore Guédin, Sébastien Fribourg, Laurent Azéma, Cécile Feuillie, Michael Molinari, Carmelo Di Primo, Philippe Barthélémy, Leblond Chain Jeanne
Publikováno v: International journal of pharmaceutics.
In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd03edb5b5cab5ad3882ba784c8d2c1
https://pubmed.ncbi.nlm.nih.gov/36587777
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6
Meeting report - first discoidin domain receptors meeting
Autor: Patrick Auguste, Birgit Leitinger, Christelle Liard, David Santamaría, Frédéric Saltel, Virginie Rocher, Laurent Azéma
For the first time, a meeting dedicated to the tyrosine kinase receptors DDR1 and DDR2 took place in Bordeaux, a famous and historical city in the south of France. Over the course of 3 days, the meeting allowed 60 participants from 11 different count
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71d647e2584ccda939bedf843d7a953
http://hdl.handle.net/10044/1/77271
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7
Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas
Autor: Marc Janier, Elsa Charignon, Catherine Savona-Baron, Jean Jacques Toulmé, Pauline Bonazza, Aref Hassan, Philippe Fernandez, Laurent Azéma, Olivier Paurelle, F. Debordeaux, David Kryza, Jacqueline Taleb, Jürgen Schulz
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Public Library of Science, 2016, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
PLoS ONE, Vol 11, Iss 2, p e0149387 (2016)
PLoS ONE, 2020, 11 (2), pp.e0149387. ⟨10.1371/journal.pone.0149387⟩
International audience; The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marke
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508a71d23191eec2fbe33900fe3c1507
https://hal.archives-ouvertes.fr/hal-02139130
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8
A colorimetric nanosensor based on a selective target-responsive aptamer kissing complex
Autor: Maxime Henry, Corinne Ravelet, Valérie Guieu, Eric Dausse, Luc Choisnard, Jean-Jacques Toulmé, Guillaume Durand, Eric Peyrin, Laurent Azéma, Emma Goux
Publikováno v: Nanoscale. 9:4048-4052
Herein, we report a novel approach for the design of a colorimetric aptasensor based on functionalized gold nanoparticle probes. This approach relies on the conjugation of nanoparticles by two functional DNA and RNA hairpins that engage specific kiss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8d9ef1d76f18cf7b648b4e26279699
https://doi.org/10.1039/c7nr00612h
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9
DNA aptamer selection in methanolic media: Adenine–aptamer as proof-of-concept
Autor: Thinhinane Chaou, Brune Vialet, Laurent Azéma
Publikováno v: Methods. 97:11-19
The major objective of this study is to investigate the usefulness of aptamers as in situ detection tool in organic solvents, which are often used for environmental extraction. But two problems related to the use of methanol-containing buffers have t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a0021f9f5ddce14eeba2cb4a021f8e
https://doi.org/10.1016/j.ymeth.2016.01.002
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10
Aptamers in Bordeaux 2017: An exceptional 'millésime'
Autor: Guillaume Durand, Eric Dausse, Laurent Azéma, Fabien Darfeuille, Jean-Jacques Toulmé, Olivier Paurelle
Publikováno v: Biochimie. 145
About 150 participants attended the symposium organised at the Palais de la Bourse in Bordeaux, France on September 22–23, 2017. Thirty speakers from all over the world delivered lectures covering selection processes, aptamer chemistry and innovati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b96fff24367c8af959b61b2d3e19284
https://pubmed.ncbi.nlm.nih.gov/29180020
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