Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laurent A. Décosterd"'
Autor:
Mattia Branca, Annalisa Marinosci, Delphine Sculier, Gilles Wandeler, Sabine Yerly, Marcel Stoeckle, Enos Bernasconi, Dominique L. Braun, Kathrin Neumann, Pietro Vernazza, Matthias Cavassini, Marta Buzzi, Laurent A. Decosterd, Patrick Schmid, Andreas Limacher, Huldrych F. Günthard, Karin J. Metzner, Alexandra Calmy
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
HIV-1 reservoir size and dynamics are promising parameters to ensure the safe prescription of simplified maintenance antiretroviral therapy in chronically HIV-1 infected patients. In the SIMPL’HIV trial, HIV-1 DNA was quantified in peripheral blood
Externí odkaz:
https://doaj.org/article/dab389ac86bc4e2e8381ca1082ecf786
Autor:
Paul Thoueille, Susana Alves Saldanha, Fabian Schaller, Aline Munting, Matthias Cavassini, Dominique Braun, Huldrych F. Günthard, Katharina Kusejko, Bernard Surial, Hansjakob Furrer, Andri Rauch, Pilar Ustero, Alexandra Calmy, Marcel Stoeckle, Manuel Battegay, Catia Marzolini, Pascal Andre, Monia Guidi, Thierry Buclin, Laurent A. Decosterd, on behalf of the Swiss HIV Cohort Study
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1588 (2022)
SHCS#879 is an ongoing Switzerland-wide multicenter observational study conducted within the Swiss HIV Cohort Study (SHCS) for the prospective follow-up of people living with HIV (PLWH) receiving long-acting injectable cabotegravir-rilpivirine (LAI-C
Externí odkaz:
https://doaj.org/article/15e8f0d929f3440aa3a0e5c7ed7a4734
Autor:
Elinam Gayi, Laurence A. Neff, Xènia Massana Muñoz, Hesham M. Ismail, Marta Sierra, Thomas Mercier, Laurent A. Décosterd, Jocelyn Laporte, Belinda S. Cowling, Olivier M. Dorchies, Leonardo Scapozza
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
X-linked myotubular myopathy (XLMTM) is a severe muscle disease with no effective treatment. Here, the authors show that tamoxifen, a drug used to treat breast cancer, rescues the pathology in a mouse model of the disease, at least in part by normali
Externí odkaz:
https://doaj.org/article/55e31f0f62ce4d928b4e2b13a82b1d60
Autor:
Paul Thoueille, Susana Alves Saldanha, Fabian Schaller, Eva Choong, Aline Munting, Matthias Cavassini, Dominique Braun, Huldrych F. Günthard, Katharina Kusejko, Bernard Surial, Hansjakob Furrer, Andri Rauch, Mathieu Rougemont, Pilar Ustero, Alexandra Calmy, Marcel Stöckle, Catia Marzolini, Caroline Di Benedetto, Enos Bernasconi, Patrick Schmid, Rein Jan Piso, Pascal Andre, François R. Girardin, Monia Guidi, Thierry Buclin, Laurent A. Decosterd
Publikováno v:
The Lancet Regional Health. Europe, Vol 36, Iss , Pp 100793- (2024)
Summary: Background: The efficacy and tolerability of long-acting cabotegravir and rilpivirine were demonstrated in Phase III trials. However, low concentrations combined with other risk factors have been associated with an increased risk of virologi
Externí odkaz:
https://doaj.org/article/6380ec40d9d94ba48ce0923cbe387561
Autor:
Niklas Köhler, Hande Karaköse, Hans-Peter Grobbel, Doris Hillemann, Sönke Andres, Christina König, Barbara Kalsdorf, Thomas Theo Brehm, Laura Böttcher, Inna Friesen, Harald Hoffmann, Dražen Strelec, Dagmar Schaub, Charles A. Peloquin, Stefan Schmiedel, Laurent A. Decosterd, Eva Choong, Sebastian G. Wicha, Rob E. Aarnoutse, Christoph Lange, Patricia M. Sánchez Carballo
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2543 (2023)
The treatment of drug-resistant Mycobacterium tuberculosis relies on complex antibiotic therapy. Inadequate antibiotic exposure can lead to treatment failure, acquired drug resistance, and an increased risk of adverse events. Therapeutic drug monitor
Externí odkaz:
https://doaj.org/article/61ae5ab8f27c42b5814e8e04b54b71a2
Autor:
Imke H. Bartelink, Pierre M. Bet, Nicolas Widmer, Monia Guidi, Erik Duijvelaar, Bram Grob, Richard Honeywell, Amanda Evelo, Ivo P. E. Tielbeek, Sue D. Snape, Henrike Hamer, Laurent A. Decosterd, Harm Jan Bogaard, Jurjan Aman, Eleonora L. Swart
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1497-1511 (2021)
Abstract This study aimed to determine whether published pharmacokinetic (PK) models can adequately predict the PK profile of imatinib in a new indication, such as coronavirus disease 2019 (COVID‐19). Total (bound + unbound) and unbound imatinib pl
Externí odkaz:
https://doaj.org/article/84259887a4a245ea94b698c03f036179
Autor:
Myriam Briki, Pascal André, Yann Thoma, Nicolas Widmer, Anna D. Wagner, Laurent A. Decosterd, Thierry Buclin, Monia Guidi, Sandro Carrara
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1283 (2023)
Therapeutic drug monitoring (TDM) of conventional cytotoxic chemotherapies is strongly supported yet poorly implemented in daily practice in hospitals. Analytical methods for the quantification of cytotoxic drugs are instead widely presented in the s
Externí odkaz:
https://doaj.org/article/8ba180fcbde64a02942f560319a292a7
Autor:
Antonia E. Schantl, Anja Verhulst, Ellen Neven, Geert J. Behets, Patrick C. D’Haese, Marc Maillard, David Mordasini, Olivier Phan, Michel Burnier, Dany Spaggiari, Laurent A. Decosterd, Mark G. MacAskill, Carlos J. Alcaide-Corral, Adriana A. S. Tavares, David E. Newby, Victoria C. Beindl, Roberto Maj, Anne Labarre, Chrismita Hegde, Bastien Castagner, Mattias E. Ivarsson, Jean-Christophe Leroux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate crystall
Externí odkaz:
https://doaj.org/article/af7eef951f974f1d9573843564c6bad9
Autor:
Paulina Biniecka, Saki Matsumoto, Axel Belotti, Jessie Joussot, Jian Fei Bai, Somi Reddy Majjigapu, Paul Thoueille, Dany Spaggiari, Vincent Desfontaine, Francesco Piacente, Santina Bruzzone, Michele Cea, Laurent A. Decosterd, Pierre Vogel, Alessio Nencioni, Michel A. Duchosal, Aimable Nahimana
Publikováno v:
Molecules, Vol 28, Iss 4, p 1897 (2023)
Targeting cancer cells that are highly dependent on the nicotinamide adenine dinucleotide (NAD+) metabolite is a promising therapeutic strategy. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme catalyzing NAD+ production. De
Externí odkaz:
https://doaj.org/article/a934d28d76cf415f8074ec99c1403245
Autor:
Philippe Rousso, Thierry Buclin, Jürg Nussberger, Laurent A. Décosterd, Salome D. La Roche, Françoise Brunner-Ferber, Hans R. Brunner, Jérôme Biollaz
Publikováno v:
Journal of hypertension. 17(3)
OBJECTIVE To investigate the endocrine and renal effects of the dual inhibitor of angiotensin converting enzyme and neutral endopeptidase, MDL 100,240. DESIGN A randomized, placebo-controlled, crossover study was performed in 12 healthy volunteers. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1653364e48d029369165ae16d1670e
https://pubmed.ncbi.nlm.nih.gov/10100082
https://pubmed.ncbi.nlm.nih.gov/10100082