Výsledky vyhledávání - "Laurent A Tremuth"

The Integrin Binding Site 2 (IBS2) in the Talin Rod Domain Is Essential for Linking Integrin β Subunits to the Cytoskeleton

Autor: Stacey Coleman, Susan J. Monkley, Erik Goormaghtigh, Laurent A Tremuth, Sophie Rodius, Patrick P.G. van der Holst, Nelly Kieffer, Michèle Moes, Corinne Kox, David R. Critchley

Publikováno v: Journal of Biological Chemistry. 282:17280-17288

Talin1 is a large cytoskeletal protein that links integrins to actin filaments through two distinct integrin binding sites, one present in the talin head domain (IBS1) necessary for integrin activation and a second (IBS2) that we have previously mapp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0532071aa2f9c336bb28a11a2ad047d4
https://doi.org/10.1074/jbc.m611846200

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A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain

Autor: Philippe Rondé, Johan Hoebeke, Sébastien Plançon, Chantal Melchior, Nelly Kieffer, Laurent A Tremuth, Kenneth Takeda, Stephanie Kreis

Publikováno v: Journal of Biological Chemistry, 279(21), 22258-22266. Baltimore, USA: American Society for Biochemistry and Molecular Biology (2004).

The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for integrin beta subunits. Here, we report the precise delimitation and a first functional analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8e100998ae94bd2b74148a94f5cf65
https://doi.org/10.1074/jbc.m400947200

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