Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Laurent Guyon"'
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Prediction of patient survival from tumor molecular ‘-omics’ data is a key step toward personalized medicine. Cox models performed on RNA profiling datasets are popular for clinical outcome predictions. But these models are ap
Externí odkaz:
https://doaj.org/article/30b3c245ac8e4908a575d64d5719bc9e
Publikováno v:
Cancers, Vol 15, Iss 10, p 2701 (2023)
Clear-cell renal cell carcinoma (ccRCC) accounts for 75% of kidney cancers. Due to the high recurrence rate and treatment options that come with high costs and potential side effects, a correct prognosis of patient survival is essential for the succe
Externí odkaz:
https://doaj.org/article/ce51ad3355f64b51875d736047a657c1
Publikováno v:
Genes, Vol 13, Iss 12, p 2275 (2022)
(1) Background: tumor profiling enables patient survival prediction. The two essential parameters to be calibrated when designing a study based on tumor profiles from a cohort are the sequencing depth of RNA-seq technology and the number of patients.
Externí odkaz:
https://doaj.org/article/c749189c10b64c6f9e20d515f4ab91f6
Autor:
Marie Arvin-Berod, Agnès Desroches-Castan, Simon Bonte, Sabine Brugière, Yohann Couté, Laurent Guyon, Jean-Jacques Feige, Isabelle Baussanne, Martine Demeunynck
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 9221-9230 (2017)
Externí odkaz:
https://doaj.org/article/aa997bbfda064c23901e9af3b3486a82
Autor:
Justine Cristante, Sayed Soha Reda El, Josiane Denis, Bruno Ragazzon, Hantel Constanze, Olivier Chabre, Laurent Guyon, Nadia Cherradi
Publikováno v:
Endocrine Abstracts.
Autor:
Soha Reda El Sayed, Justine Cristante, Laurent Guyon, Josiane Denis, Olivier Chabre, Nadia Cherradi
Publikováno v:
Cancers, Vol 13, Iss 11, p 2680 (2021)
The discovery of microRNAs (miRNAs) in 1993 has challenged the dogma of gene expression regulation. MiRNAs affect most of cellular processes from metabolism, through cell proliferation and differentiation, to cell death. In cancer, deregulated miRNA
Externí odkaz:
https://doaj.org/article/ffe21a2ab66445d6884eb1295eb21626
Autor:
Rita El Helou, Guillaume Pinna, Olivier Cabaud, Julien Wicinski, Ricky Bhajun, Laurent Guyon, Claire Rioualen, Pascal Finetti, Abigaelle Gros, Bernard Mari, Pascal Barbry, Francois Bertucci, Ghislain Bidaut, Annick Harel-Bellan, Daniel Birnbaum, Emmanuelle Charafe-Jauffret, Christophe Ginestier
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2256-2268 (2017)
Summary: Breast cancer stem cells (bCSCs) have been implicated in tumor progression and therapeutic resistance; however, the molecular mechanisms that define this state are unclear. We have performed two microRNA (miRNA) gain- and loss-of-function sc
Externí odkaz:
https://doaj.org/article/46925da2e0104ddc8a207b5df794202d
Autor:
Justine Cristante, Soha Reda El Sayed, Josiane Denis, Bruno Ragazzon, Constanze Hantel, Olivier Chabre, Laurent Guyon, Nadia Cherradi
Adrenocortical carcinoma (ACC) is a rare malignancy with dismal prognosis. Deregulated microRNA (miRNA) expression has been implicated in ACC aggressiveness. Nevertheless, the mechanisms underlying such deregulations remain unknown. Aberrant Wnt/β-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffea1386e6ae5bd3bf46ce30a914c22
https://doi.org/10.1101/2023.02.10.527992
https://doi.org/10.1101/2023.02.10.527992
Autor:
Sofia Giacosa, Catherine Pillet, Irinka Séraudie, Laurent Guyon, Yann Wallez, Caroline Roelants, Christophe Battail, Bertrand Evrard, Frédéric Chalmel, Caroline Barette, Emmanuelle Soleilhac, Marie-Odile Fauvarque, Quentin Franquet, Clément Sarrazin, Nicolas Peilleron, Gaëlle Fiard, Jean-Alexandre Long, Jean-Luc Descotes, Claude Cochet, Odile Filhol
Publikováno v:
Cancers, Vol 13, Iss 3, p 576 (2021)
Kinase-targeted agents demonstrate antitumor activity in advanced metastatic clear cell renal cell carcinoma (ccRCC), which remains largely incurable. Integration of genomic approaches through small-molecules and genetically based high-throughput scr
Externí odkaz:
https://doaj.org/article/a9cddb0170b449938a2e87cf0a411bed
Autor:
Maurine Oreglia, Silviu Sbiera, Martin Fassnacht, Laurent Guyon, Josiane Denis, Justine Cristante, Olivier Chabre, Nadia Cherradi
Publikováno v:
Cancers, Vol 12, Iss 3, p 724 (2020)
We have previously identified serum miR-483-5p as a preoperative diagnosis and prognosis biomarker for adrenocortical cancer (ACC). Here, we aimed to determine whether circulating miR-483-5p levels measured 3 months post-operatively distinguished pat
Externí odkaz:
https://doaj.org/article/5aac4ebc321f41659faa0a25cebba3ab