Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Laurent, Tesson"'
Autor:
Séverine Ménoret, Laurent Tesson, Séverine Remy, Victor Gourain, Céline Sérazin, Claire Usal, Aude Guiffes, Vanessa Chenouard, Laure-Hélène Ouisse, Malika Gantier, Jean-Marie Heslan, Cynthia Fourgeux, Jeremie Poschmann, Carole Guillonneau, Ignacio Anegon
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Regulatory T cells (Treg) in diverse species include CD4+ and CD8+ T cells. In all species, CD8+ Treg have been only partially characterized and there is no rat model in which CD4+ and CD8+ FOXP3+ Treg are genetically tagged. Resu
Externí odkaz:
https://doaj.org/article/a5f7fd4d1ec14f8a9408162e7c0a4594
Autor:
Matthieu Leuillier, Thomas Duflot, Séverine Ménoret, Hind Messaoudi, Zoubir Djerada, Déborah Groussard, Raphaël G.P. Denis, Laurence Chevalier, Ahmed Karoui, Baptiste Panthu, Pierre-Alain Thiébaut, Isabelle Schmitz-Afonso, Séverine Nobis, Cynthia Campart, Tiphaine Henry, Camille Sautreuil, Serge H. Luquet, Olivia Beseme, Catherine Féliu, Hélène Peyret, Lionel Nicol, Jean-Paul Henry, Sylvanie Renet, Paul Mulder, Debin Wan, Laurent Tesson, Jean-Marie Heslan, Angéline Duché, Sébastien Jacques, Frédéric Ziegler, Valéry Brunel, Gilles J.P. Rautureau, Christelle Monteil, Jean-Luc do Rego, Jean-Claude do Rego, Carlos Afonso, Bruce Hammock, Anne-Marie Madec, Florence Pinet, Vincent Richard, Ignacio Anegon, Christophe Guignabert, Christophe Morisseau, Jérémy Bellien
Publikováno v:
Journal of Advanced Research, Vol 43, Iss , Pp 163-174 (2023)
Introduction: Although the physiological role of the C-terminal hydrolase domain of the soluble epoxide hydrolase (sEH-H) is well investigated, the function of its N-terminal phosphatase activity (sEH-P) remains unknown. Objectives: This study aimed
Externí odkaz:
https://doaj.org/article/ae3d2c7efa674a65a28617072bd9a0df
Autor:
Sandra Martin Lorenzo, Maria del Mar Muniz Moreno, Helin Atas, Marion Pellen, Valérie Nalesso, Wolfgang Raffelsberger, Geraldine Prevost, Loic Lindner, Marie-Christine Birling, Séverine Menoret, Laurent Tesson, Luc Negroni, Jean-Paul Concordet, Ignacio Anegon, Yann Herault
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Copy number variations (CNVs) of the human 16p11.2 locus are associated with several developmental/neurocognitive syndromes. Particularly, deletion and duplication of this genetic interval are found in patients with autism spectrum disorders, intelle
Externí odkaz:
https://doaj.org/article/e090825d4e2b438eba92293661a994d6
Autor:
Vanessa Chenouard, Isabelle Leray, Laurent Tesson, Severine Remy, Alasdair Allan, Daniel Archer, Adam Caulder, Agnès Fortun, Karine Bernardeau, Yacine Cherifi, Lydia Teboul, Laurent David, Ignacio Anegon
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106399- (2023)
Summary: CRISPR-Cas9 cleavage efficacy and accuracy are the main challenges gene editing faces, and they are particularly affected by the optimal formation of the ribonucleoprotein (RNP) complex. We used nano differential scanning fluorimetry, a labe
Externí odkaz:
https://doaj.org/article/3e4821e8ad1840e39504e69a7b2227d8
Autor:
Antoine Freuchet, Apolline Salama, Séverine Bézie, Laurent Tesson, Séverine Rémy, Romain Humeau, Hadrien Règue, Céline Sérazin, Léa Flippe, Pärt Peterson, Nadège Vimond, Claire Usal, Séverine Ménoret, Jean‐Marie Heslan, Franck Duteille, Frédéric Blanchard, Magali Giral, Marco Colonna, Ignacio Anegon, Carole Guillonneau
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Background Immune homeostasis requires fully functional Tregs with a stable phenotype to control autoimmunity. Although IL‐34 is a cytokine first described as mainly involved in monocyte cell survival and differentiation, we recently described its
Externí odkaz:
https://doaj.org/article/66e3ea0bfcc54419864f02858ee50ceb
Autor:
Justine Dhot, Marine Ferron, Valentine Prat, Antoine Persello, David Roul, David Stévant, Damien Guijarro, Nicolas Piriou, Virginie Aillerie, Angélique Erraud, Gilles Toumaniantz, Morteza Erfanian, Angela Tesse, Amandine Grabherr, Laurent Tesson, Séverine Menoret, Ignacio Anegon, Jean‐Noël Trochu, Marja Steenman, Michel De Waard, Bertrand Rozec, Benjamin Lauzier, Chantal Gauthier
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 4159-4171 (2020)
Abstract Aims Diastolic dysfunction is common in cardiovascular diseases, particularly in the case of heart failure with preserved ejection fraction. The challenge is to develop adequate animal models to envision human therapies in the future. It has
Externí odkaz:
https://doaj.org/article/303759f709374a3a807f6f14fd31e462
Autor:
Elise Dreano, Marc Bacchetta, Juliette Simonin, Louise Galmiche, Claire Usal, Lotfi Slimani, Jérémy Sadoine, Laurent Tesson, Ignacio Anegon, Jean‐Paul Concordet, Aurélie Hatton, Lucile Vignaud, Danielle Tondelier, Isabelle Sermet‐Gaudelus, Marc Chanson, Charles‐Henry Cottart
Publikováno v:
Animal Models and Experimental Medicine, Vol 2, Iss 4, Pp 297-311 (2019)
Abstract Background Genetically engineered animals are essential for gaining a proper understanding of the disease mechanisms of cystic fibrosis (CF). The rat is a relevant laboratory model for CF because of its zootechnical capacity, size, and airwa
Externí odkaz:
https://doaj.org/article/01f6cdbc742344189519f5234c21b399
Autor:
Vanessa Chenouard, Séverine Remy, Laurent Tesson, Séverine Ménoret, Laure-Hélène Ouisse, Yacine Cherifi, Ignacio Anegon
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The rat has been extensively used as a small animal model. Many genetically engineered rat models have emerged in the last two decades, and the advent of gene-specific nucleases has accelerated their generation in recent years. This review covers the
Externí odkaz:
https://doaj.org/article/e447d794606b46ef88790cf52646f4bc
Autor:
Florian Dubois, Anne Gaignerie, Léa Flippe, Jean-Marie Heslan, Laurent Tesson, Mélanie Chesneau, Fabienne Haspot, Sophie Conchon, Laurent David, Sophie Brouard
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243769 (2020)
The success of inducing human pluripotent stem cells (hIPSC) offers new opportunities for cell-based therapy. Since B cells exert roles as effector and as regulator of immune responses in different clinical settings, we were interested in generating
Externí odkaz:
https://doaj.org/article/1807caffb4164881808bdbbac8c004ff
Autor:
Laure-Hélène Ouisse, Séverine Remy, Aude Lafoux, Thibaut Larcher, Laurent Tesson, Vanessa Chenouard, Carole Guillonneau, Lucas Brusselle, Nadège Vimond, Karl Rouger, Yann Péréon, Alexis Chenouard, Christèle Gras-Le Guen, Cécile Braudeau, Régis Josien, Corinne Huchet, Ignacio Anegon
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Corticosteroids (CS) are standard therapy for the treatment of Duchenne's muscular dystrophy (DMD). Even though they decrease inflammation, they have limited efficacy and are associated with significant side effects. There is therefore the need for n
Externí odkaz:
https://doaj.org/article/a2895734cf364d49af8e3fda50f3a486