Zobrazeno 1 - 10 of 86 pro vyhledávání: '"Laurent, Mauvieux"'
1
Akademický článek
TLRs1-10 Protein Expression in Circulating Human White Blood Cells during Bacterial and COVID-19 Infections
Autor: Louise Chomel, Mathieu Vogt, Julien Demiselle, Pierrick Le Borgne, Marine Tschirhart, Valentin Morandeau, Hamid Merdji, Laurent Miguet, Julie Helms, Ferhat Meziani, Laurent Mauvieux
Publikováno v: Journal of Innate Immunity, Pp 1-1 (2024)
Introduction: Toll-like receptors play crucial roles in the sepsis-induced systemic inflammatory response. Septic shock mortality correlates with overexpression of neutrophilic TLR2 and TLR9, while the role of TLR4 overexpression remains a debate. In
Externí odkaz: https://doaj.org/article/c84cf3857ea24c17a4a735af9dbbd1ab
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2
Akademický článek
CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition
Autor: Ava Galland, Victor Gourain, Karima Habbas, Yonca Güler, Elisabeth Martin, Claudine Ebel, Manuela Tavian, Laurent Vallat, Marie‐Pierre Chenard, Laurent Mauvieux, Jean‐Noël Freund, Isabelle Duluc, Claire Domon‐Dell
Publikováno v: Molecular Oncology, Vol 15, Iss 9, Pp 2318-2329 (2021)
The intestine‐specific caudal‐related homeobox gene‐2 (CDX2) homeobox gene, while being a tumor suppressor in the gut, is ectopically expressed in a large proportion of acute leukemia and is associated with poor prognosis. Here, we report that
Externí odkaz: https://doaj.org/article/897ff20dc4204936a7914f96da43039a
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3
Akademický článek
Tuberculosis and atypical mycobacterial infections in ruxolitinib-treated patients with primary or secondary myelofibrosis or polycythemia vera
Autor: Sylvain Lescuyer, Marie-Pierre Ledoux, Simon Gravier, Shanti Natarajan-Amé, Céline Duval, Fréderic Maloisel, Laurent Mauvieux, Elise Toussaint, Luc-Matthieu Fornecker, Raoul Herbrecht
Publikováno v: International Journal of Infectious Diseases, Vol 80, Iss , Pp 134-136 (2019)
Ruxolitinib is a JAK-1/JAK-2 inhibitor indicated for the treatment of polycythemia vera and primary or secondary myelofibrosis. Only one patient (0.2%) was diagnosed with tuberculosis among the 485 patients receiving ruxolitinib in the four pivotal t
Externí odkaz: https://doaj.org/article/2c7fd0a65e724abc9d6aeed1f1e3359a
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6
Akademický článek
Sumoylation Inhibits the Growth Suppressive Properties of Ikaros.
Autor: Apostol Apostolov, Isma Litim-Mecheri, Attila Oravecz, Marie Goepp, Peggy Kirstetter, Patricia Marchal, Antoine Ittel, Laurent Mauvieux, Susan Chan, Philippe Kastner
Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157767 (2016)
The Ikaros transcription factor is a tumor suppressor that is also important for lymphocyte development. How post-translational modifications influence Ikaros function remains partially understood. We show that Ikaros undergoes sumoylation in develop
Externí odkaz: https://doaj.org/article/9c9ee37e3a5f469f8a7adf1a80ad1587
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7
Akademický článek
Myeloid Sarcoma of the Uterine Cervix as Presentation of Acute Myeloid Leukaemia after Treatment with Low-Dose Radioiodine for Thyroid Cancer: A Case Report and Review of the Literature
Autor: Anne Sophie Weingertner, Marc Wilt, Ihab Atallah, Cécile Fohrer, Laurent Mauvieux, Jean-François Rodier
Publikováno v: Case Reports in Oncology, Vol 2, Iss 1, Pp 1-6 (2009)
The development of acute myeloid leukaemia after low-dose radioiodine therapy and its presentation as a myeloid sarcoma of the uterine cervix are both rare events. We report a case of acute myeloid leukaemia revealed by a myeloid sarcoma of the uteri
Externí odkaz: https://doaj.org/article/0ef7c124636445ef8e6435b9882d49fb
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8
Standardisation of pathogenicity classification for somatic alterations in solid tumours and haematologic malignancies
Autor: Laurent Miguet, Florence Coulet, Celine Guien, Lucie Karayan-Tapon, Isabelle Soubeyran, Anne Cayre, Laurent Mauvieux, Etienne Muller, Karen Leroy, Alexandre Harlé, Christophe Béroud, Olfa Trabelsi Grati, Pierre Sujobert, Etienne Rouleau, Alexandra Lespagnol, Gaëlle Tachon, Florence Koeppel, Claude Preudhomme, David Salgado, Olivier Kosmider
Publikováno v: European Journal of Cancer
European Journal of Cancer, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
European Journal of Cancer, Elsevier, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
International audience; Background: The difficulty in interpreting somatic alterations is correlated with the increase in sequencing panel size. To correctly guide the clinical management of patients with cancer, there needs to be accurate classifica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0543125e44b1e51aec427352cd59511
https://hal.science/hal-03408473
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10
CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGF�� inhibition
Autor: Claire Domon-Dell, Karima Habbas, Ava Galland, Isabelle Duluc, Yonca Güler, Jean-Noël Freund, Marie-Pierre Chenard, Claudine Ebel, Manuela Tavian, Laurent Vallat, Elisabeth Martin, Victor Gourain, Laurent Mauvieux
Publikováno v: Molecular Oncology
Molecular Oncology, Vol 15, Iss 9, Pp 2318-2329 (2021)
Molecular Oncology, 2021, 15 (9), pp.2318-2329. ⟨10.1002/1878-0261.12982⟩
Molecular Oncology, 15 (9), 2318-2329
The intestine‐specific caudal‐related homeobox gene‐2 (CDX2) homeobox gene, while being a tumor suppressor in the gut, is ectopically expressed in a large proportion of acute leukemia and is associated with poor prognosis. Here, we report that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bb3232d4a51fc76d4dd8269cae84ae
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