Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Laurent, Jacob"'
Autor:
Charlotte Genestet, Guislaine Refrégier, Elisabeth Hodille, Rima Zein-Eddine, Adrien Le Meur, Fiona Hak, Alexia Barbry, Emilie Westeel, Jean-Luc Berland, Astrid Engelmann, Isabelle Verdier, Gérard Lina, Florence Ader, Stéphane Dray, Laurent Jacob, François Massol, Samuel Venner, Oana Dumitrescu
Publikováno v:
International Journal of Infectious Diseases, Vol 125, Iss , Pp 74-83 (2022)
ABSTRACT: Objectives: Mycobacterium tuberculosis (Mtb) infections result in a wide spectrum of clinical presentations but without proven Mtb genetic determinants. Herein, we hypothesized that the genetic features of Mtb clinical isolates, such as spe
Externí odkaz:
https://doaj.org/article/3131c6b37e154dc0ae4667bf1158cc63
Autor:
Diane Friedman, Lamiae Grimaldi, Alain Cariou, Philippe Aegerter, Stéphane Gaudry, Abdel Ben Salah, Haikel Oueslati, Bruno Megarbane, Nicolas Meunier-Beillard, Jean-Pierre Quenot, Carole Schwebel, Laurent Jacob, Ségloène Robin Lagandré, Pierre Kalfon, Romain Sonneville, Shidasp Siami, Aurelien Mazeraud, Tarek Sharshar
Publikováno v:
JMIR Research Protocols, Vol 12, p e47929 (2023)
Externí odkaz:
https://doaj.org/article/f2564283eca44835b8385d4d949d1e9b
Autor:
Kevin Boyé, Luiz Henrique Geraldo, Jessica Furtado, Laurence Pibouin-Fragner, Mathilde Poulet, Doyeun Kim, Bryce Nelson, Yunling Xu, Laurent Jacob, Nawal Maissa, Dritan Agalliu, Lena Claesson-Welsh, Susan L. Ackerman, Anne Eichmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The authors show that Netrin-1-Unc5B signaling controls blood-brain barrier integrity by maintaining Wnt/b-catenin signaling and that delivery of antibodies blocking Netrin-1 binding to Unc5B causes transient and size-selective BBB breakdown.
Externí odkaz:
https://doaj.org/article/7945797555614051a865fa97526dfd6d
Autor:
Diane Friedman, Lamiae Grimaldi, Alain Cariou, Philippe Aegerter, Stéphane Gaudry, Abdel Ben Salah, Haikel Oueslati, Bruno Megarbane, Nicolas Meunier-Beillard, Jean-Pierre Quenot, Carole Schwebel, Laurent Jacob, Ségloène Robin Lagandré, Pierre Kalfon, Romain Sonneville, Shidasp Siami, Aurelien Mazeraud, Tarek Sharshar
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 5, p e30496 (2022)
BackgroundCritically ill patients are at risk of developing a postintensive care syndrome (PICS), which is characterized by physical, psychological, and cognitive impairments and which dramatically impacts the patient’s quality of life (QoL). No in
Externí odkaz:
https://doaj.org/article/3b2c9d7e558a4662ae506d48704bda78
Autor:
Laurent Jacob, Ligia Simoes Braga Boisserand, Luiz Henrique Medeiros Geraldo, Jose de Brito Neto, Thomas Mathivet, Salli Antila, Besma Barka, Yunling Xu, Jean-Mickael Thomas, Juliette Pestel, Marie-Stéphane Aigrot, Eric Song, Harri Nurmi, Seyoung Lee, Kari Alitalo, Nicolas Renier, Anne Eichmann, Jean-Leon Thomas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The lymphatic vasculature is essential to maintain fluid homeostasis and immune surveillance, including in the brain where lymphatic vessels were only recently identified. Here, Jacob et al. provide an anatomical map of lymphatic vessels in the verte
Externí odkaz:
https://doaj.org/article/f862bbf03fb24688bc31ebcccca23429
Autor:
Fabien Binamé, Lucas D Pham‐Van, Caroline Spenlé, Valérie Jolivel, Dafni Birmpili, Lionel A Meyer, Laurent Jacob, Laurence Meyer, Ayikoé G Mensah‐Nyagan, Chrystelle Po, Michaël Van der Heyden, Guy Roussel, Dominique Bagnard
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 11, Pp 1-16 (2019)
Abstract Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of the disease, but no drugs are currently available to repair lesions. Our study identifies in MS patients the overexpression of Plexin‐A1, the signal
Externí odkaz:
https://doaj.org/article/9c93a265f0e349ccb476894277fab549
Autor:
Hussein Ghazale, Chantal Ripoll, Nicolas Leventoux, Laurent Jacob, Safa Azar, Daria Mamaeva, Yael Glasson, Charles-Felix Calvo, Jean-Leon Thomas, Sarah Meneceur, Yvan Lallemand, Valérie Rigau, Florence E. Perrin, Harun N. Noristani, Brenda Rocamonde, Emmanuelle Huillard, Luc Bauchet, Jean-Philippe Hugnot
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1159-1177 (2019)
Summary: Anamniotes, rodents, and young humans maintain neural stem cells in the ependymal zone (EZ) around the central canal of the spinal cord, representing a possible endogenous source for repair in mammalian lesions. Cell diversity and genes spec
Externí odkaz:
https://doaj.org/article/705f9ae190674326953c60e1d157bba2
Autor:
Laurent Jacob, Terence P. Speed
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-3 (2018)
Abstract In a recent publication, Sood et al. (Genome Biol 16:185, 2015) presented a set of 150 probe sets that could be used in the diagnosis of Alzheimer’s disease (AD) based on gene expression. We reproduce some of their experiments and show tha
Externí odkaz:
https://doaj.org/article/85d7fad8ddff48a7ba0acd96fdeee74a
Autor:
Marc J. van de Vijver, Brigitte Sigal-Zafrani, Emmanuel Barillot, Harry Bartelink, Alain Fourquet, Rim Hadhri, Philippe Hupé, Ron M. Kerkhoven, Daoud Sie, Laurent Jacob, Bas Kreike, Kevin Bleakley, Hans Halfwerk, Marc A. Bollet, Nicolas Servant
Purpose: A gene expression signature, predictive for local recurrence after breast-conserving treatment, has previously been identified from a series of 165 young patients with breast cancer. We evaluated this signature on both another platform and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dac4bb284a408b0109451c08275aa37
https://doi.org/10.1158/1078-0432.c.6520737.v1
https://doi.org/10.1158/1078-0432.c.6520737.v1
Autor:
Marc J. van de Vijver, Brigitte Sigal-Zafrani, Emmanuel Barillot, Harry Bartelink, Alain Fourquet, Rim Hadhri, Philippe Hupé, Ron M. Kerkhoven, Daoud Sie, Laurent Jacob, Bas Kreike, Kevin Bleakley, Hans Halfwerk, Marc A. Bollet, Nicolas Servant
PDF file - 203K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44014ff9423e59c5e3b98cd05224296c
https://doi.org/10.1158/1078-0432.22446390
https://doi.org/10.1158/1078-0432.22446390