Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Laurent, Gautron"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The communication between intestinal Glucagon like peptide 1 (GLP-1)-producing cells and the peripheral nervous system has garnered renewed interest considering the availability of anti-obesity and anti-diabetic approaches targeting GLP-1 si
Externí odkaz:
https://doaj.org/article/aaf2eea7fceb42a5a09d5a82a2d01b62
Autor:
Yeshumenesh Zegeye, Bogale Aredo, Seher Yuksel, Dogan Can Kirman, Ashwani Kumar, Bo Chen, Emily Turpin, Sangita Shresta, Yu-Guang He, Laurent Gautron, Miao Tang, Xiaohong Li, Sophia M. DiCesare, John D. Hulleman, Chao Xing, Sara Ludwig, Eva Marie Y. Moresco, Bruce A. Beutler, Rafael L. Ufret-Vincenty
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Activated microglia have been implicated in the pathogenesis of age-related macular degeneration (AMD), diabetic retinopathy, and other neurodegenerative and neuroinflammatory disorders, but our understanding of the mechanisms behind their a
Externí odkaz:
https://doaj.org/article/9429c796dd824374af717a5bef932a51
Autor:
Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is un
Externí odkaz:
https://doaj.org/article/6885cd75dd3641e481d840972315e815
Autor:
Seher Yuksel, Bogale Aredo, Yeshumenesh Zegeye, Cynthia X. Zhao, Miao Tang, Xiaohong Li, John D. Hulleman, Laurent Gautron, Sara Ludwig, Eva M. Y. Moresco, Igor A. Butovich, Bruce A. Beutler, Rafael L. Ufret-Vincenty
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Microglia play a role in the pathogenesis of many retinal diseases. Fundus spots in mice often correlate with the accumulation of activated subretinal microglia. Here we use a semiquantitative fundus spot scoring scale in combination with an
Externí odkaz:
https://doaj.org/article/3683c57a77574449a41c1f5040bcfed1
Publikováno v:
PeerJ, Vol 12, p e16739 (2024)
GPR149 is an orphan receptor about which little is known. Accordingly, in the present study, we mapped the tissue expression of Gpr149 in mice using three complementary approaches: quantitative PCR, in situ hybridization, and a newly generated Gpr149
Externí odkaz:
https://doaj.org/article/57688c130cfa45dda459ec7d8546c6a8
Autor:
Mario Perelló, María P. Cornejo, Pablo N. De Francesco, Gimena Fernandez, Laurent Gautron, Lesly S. Valdivia
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 228-239 (2022)
Ghrelin is a stomach-derived peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) and displays a plethora of neuroendocrine, metabolic, autonomic and behavioral actions. It has been proposed that some actions of ghrelin are e
Externí odkaz:
https://doaj.org/article/3f1ae742e2b7487a94bc135b69673889
Autor:
Tyler M. Cook, Chaitanya K. Gavini, Jason Jesse, Gregory Aubert, Emily Gornick, Raiza Bonomo, Laurent Gautron, Brian T. Layden, Virginie Mansuy-Aubert
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101350- (2021)
Objective: The vagus nerve provides a direct line of communication between the gut and the brain for proper regulation of energy balance and glucose homeostasis. Short-chain fatty acids (SCFAs) produced via gut microbiota fermentation of dietary fibe
Externí odkaz:
https://doaj.org/article/6021c23c9708486eb0d022d0dca9362c
Autor:
Laurent Gautron
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The excitation of vagal mechanoreceptors located in the stomach wall directly contributes to satiation. Thus, a loss of gastric innervation would normally be expected to result in abrogated satiation, hyperphagia, and unwanted weight gain. While Roux
Externí odkaz:
https://doaj.org/article/997f26e9ac1543ba95c6f8ab9e5f767e
Autor:
Laurent Gautron
Publikováno v:
médecine/sciences. 39:170-176
L’article de Romain Brette, récemment publié dans médecine/sciences, décrivait le modèle managérial de la recherche biomédicale comme « profondément dysfonctionnel ». Nous souscrivons à cette critique et apportons dans ce nouvel article,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee1b50e0b556fa509eca6fc1616809c1
https://doi.org/10.1051/medsci/2023004
https://doi.org/10.1051/medsci/2023004