Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Laurent, Désaubry"'
Autor:
Junmei Liu, Ranran Zhang, Tong Su, Qianqian Zhou, Lin Gao, Zongyue He, Xin Wang, Jian Zhao, Yuanxin Xing, Feifei Sun, Wenjie Cai, Xinpei Wang, Jingying Han, Ruixi Qin, Laurent Désaubry, Bo Han, Weiwen Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Castration-resistant prostate cancer (CRPC) is currently the main challenge for prostate cancer (PCa) treatment, and there is an urgent need to find novel therapeutic targets and drugs. Prohibitin (PHB1) is a multifunctional chape
Externí odkaz:
https://doaj.org/article/fbe6f91d94f84e458adbace90b04f277
Autor:
Wei Yang, Bo Mu, Jing You, Chenyu Tian, Huachao Bin, Zhiqiang Xu, Liting Zhang, Ronggang Ma, Ming Wu, Guo Zhang, Chong Huang, Linli Li, Zhenhua Shao, Lunzhi Dai, Laurent Désaubry, Shengyong Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Ferroptosis is a promising therapeutic target for a variety of diseases, but a majority of known ferroptosis inhibitors belong to either antioxidants or iron chelators. Here, the authors discover a new non-classical small molecule inhibitor that is a
Externí odkaz:
https://doaj.org/article/5bae468ec3a34502ae52c86217dd6b9b
Autor:
Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loic Ysebaert, Jean-Hugues François, Susan Cortez, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti, Etienne Moussay
Publikováno v:
HemaSphere, Vol 7, p e52627ab (2023)
Externí odkaz:
https://doaj.org/article/cadb7e0ab439425bb2d02339f658e7b0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Annexin A2 (AnxA2) plays a critical role in cell transformation, immune response, and resistance to cancer therapy. Besides functioning as a calcium- and lipidbinding protein, AnxA2 also acts as an mRNA-binding protein, for instance, by
Externí odkaz:
https://doaj.org/article/3362a26f2401430d93c5c6cc26c9ad4a
Autor:
Ahmad Najem, Mohammad Krayem, Serena Sabbah, Matilde Pesetti, Fabrice Journe, Ahmad Awada, Laurent Désaubry, Ghanem E. Ghanem
Publikováno v:
Cells, Vol 12, Iss 14, p 1855 (2023)
Despite important advances in the treatment of metastatic melanoma with the development of MAPK-targeted agents and immune checkpoint inhibitors, the majority of patients either do not respond to therapies or develop acquired resistance. Furthermore,
Externí odkaz:
https://doaj.org/article/6ce40f86795447d1bffe6e7fe1ad41b4
Autor:
Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Glioblastoma (GBM) is one of the most aggressive types of cancer, which begins within the brain. It is the most invasive type of glioma developed from astrocytes. Until today, Temozolomide (TMZ) is the only standard chemotherapy for patients
Externí odkaz:
https://doaj.org/article/b7f71d227f1e45b69f1e97f821dc7517
Autor:
Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/bb319a500c6044828a6328edb4358d50
Autor:
Karen A. Conrad, Hyunjeong Kim, Mohammad Qasim, Amel Djehal, Aaron D. Hernday, Laurent Désaubry, Jason M. Rauceo
Publikováno v:
Pathogens, Vol 12, Iss 1, p 126 (2023)
Invasive fungal infections caused by Candida species remain a significant public health problem worldwide. The increasing prevalence of drug-resistant infections and a limited arsenal of antifungal drugs underscore the need for novel interventions. H
Externí odkaz:
https://doaj.org/article/526376f0a0d9415ea385864e2868926d
Autor:
Hafidha Bentayeb, Marine Aitamer, Barbara Petit, Lydie Dubanet, Sabria Elderwish, Laurent Désaubry, Armand de Gramont, Eric Raymond, Agnès Olivrie, Julie Abraham, Marie-Odile Jauberteau, Danielle Troutaud
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background Diffuse large B-cell lymphomas (DLBCLs) are aggressive lymphomas accounting for approximately a third of non-Hodgkin lymphomas. Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are scaffold proteins that promote mitochondria homeostasi
Externí odkaz:
https://doaj.org/article/2f144c082943417e80c986adb6220bb5
Autor:
Adeline Gasser, PhD, Yu-Wen Chen, MD, PhD, Anais Audebrand, MSci, Ayhan Daglayan, MSci, Marine Charavin, PhD, Brigitte Escoubet, MD, PhD, Pavel Karpov, PhD, Igor Tetko, PhD, Michael W.Y. Chan, PhD, Daniela Cardinale, MD, PhD, Laurent Désaubry, PhD, Canan G. Nebigil, PharmD, PhD
Publikováno v:
JACC. CardioOncology, Vol 1, Iss 1, Pp 84-102 (2019)
Objectives: This study investigated how different concentrations of doxorubicin (DOX) can affect the function of cardiac cells. This study also examined whether activation of prokineticin receptor (PKR)-1 by a nonpeptide agonist, IS20, prevents DOX-i
Externí odkaz:
https://doaj.org/article/084a7eda97e34e36bf013fb6c4afb797