Zobrazeno 1 - 10 of 116 pro vyhledávání: '"Laurent, Brard"'
1
Akademický článek
Our current understanding of the biological impact of endometrial cancer mtDNA genome mutations and their potential use as a biomarker
Autor: Pabitra Khadka, Carolyn K. J. Young, Ravi Sachidanandam, Laurent Brard, Matthew J. Young
Publikováno v: Frontiers in Oncology, Vol 14 (2024)
Endometrial cancer (EC) is a devastating and common disease affecting women’s health. The NCI Surveillance, Epidemiology, and End Results Program predicted that there would be >66,000 new cases in the United States and >13,000 deaths from EC in 202
Externí odkaz: https://doaj.org/article/eb9d9eff578a4b9ab076cec4ab9f3ab3
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2
Akademický článek
Assessment of the diagnostic and prognostic relevance of ACAT1 and CE levels in plasma, peritoneal fluid and tumor tissue of epithelial ovarian cancer patients - a pilot study
Autor: Vijayalakshmi Ayyagari, Maio Li, Zvi Pasman, Xinjia Wang, Somaja Louis, Paula Diaz-Sylvester, Kathleen Groesch, Teresa Wilson, Laurent Brard
Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Abnormal accumulation of acyl-CoA cholesterol acyltransferase-1 (ACAT1) and ACAT1-mediated cholesterol esterified with fatty acids (CE) contribute to cancer progression in various cancers. Our findings of increased CE and ACAT1 le
Externí odkaz: https://doaj.org/article/6bf523f619c84a648fe32dd3716b6c43
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3
Akademický článek
Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenanes in Tumor Specimens Obtained from Three Endometrial Cancer Patients
Autor: Matthew J. Young, Ravi Sachidanandam, Dale B. Hales, Laurent Brard, Kathy Robinson, Md. Mostafijur Rahman, Pabitra Khadka, Kathleen Groesch, Carolyn K. J. Young
Publikováno v: Life, Vol 12, Iss 4, p 562 (2022)
Endometrial carcinoma (EC) is the most common type of gynecologic malignant epithelial tumor, with the death rate from this disease doubling over the past 20 years. Mitochondria provide cancer cells with necessary anabolic building blocks such as ami
Externí odkaz: https://doaj.org/article/1febeb1966ca40fb9c7f64ecdfca5be1
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4
Akademický článek
Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer.
Autor: Ruizhong Miao, Taylor C Badger, Kathleen Groesch, Paula L Diaz-Sylvester, Teresa Wilson, Allen Ghareeb, Jongjin Anne Martin, Melissa Cregger, Michael Welge, Colleen Bushell, Loretta Auvil, Ruoqing Zhu, Laurent Brard, Andrea Braundmeier-Fleming
Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227707 (2020)
Epithelial ovarian cancer (OC) is the most deadly cancer of the female reproductive system. To date, there is no effective screening method for early detection of OC and current diagnostic armamentarium may include sonographic grading of the tumor an
Externí odkaz: https://doaj.org/article/2f9429bdc7964d1695a50621cbb6904a
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5
Akademický článek
Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression-An in vitro study.
Autor: Vijayalakshmi N Ayyagari, Xinjia Wang, Paula L Diaz-Sylvester, Kathleen Groesch, Laurent Brard
Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0228024 (2020)
Abnormal accumulation of acyl-CoA cholesterol acyltransferase-1 (ACAT-1) mediated cholesterol ester has been shown to contribute to cancer progression in various cancers including leukemia, glioma, breast, pancreatic and prostate cancers. However, th
Externí odkaz: https://doaj.org/article/f272d5a44a8e47aaa4dd15af72adade1
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