Zobrazeno 1 - 10
of 416
pro vyhledávání: '"Laurens T"'
IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia
Autor:
Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
IKZF1-deletions occur in 10-15% of patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) and predict a poor outcome. However, the impact of IKZF1-loss on sensitivity to drugs used in contemporary treatment protocols has remained under
Externí odkaz:
https://doaj.org/article/70f5749bff5943bb9814e9df3159f0f2
Publikováno v:
npj Quantum Information, Vol 9, Iss 1, Pp 1-5 (2023)
Abstract In research concerning quantum networks, it is often assumed that the parties can classically communicate with each other. However, classical communication might introduce a substantial delay to the network, especially if it is large. As the
Externí odkaz:
https://doaj.org/article/b24624e72c4148eb84f3b443a316b59a
Autor:
Willem P.J. Cox, Nils Evander, Dorette S. van Ingen Schenau, Gawin R. Stoll, Nadia Anderson, Lieke de Groot, Kari J.T. Grünewald, Rico Hagelaar, Miriam Butler, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
In pediatric acute lymphoblastic leukemia (ALL), mutations/deletions affecting the TP53 gene are rare at diagnosis. However, at relapse about 12% of patients show TP53 aberrations, which are predictive of a very poor outcome. Since p53-mediated apopt
Externí odkaz:
https://doaj.org/article/986ac4b3aae24d9999fc92fcd6366f17
Publikováno v:
Light: Science & Applications, Vol 11, Iss 1, Pp 1-24 (2022)
Liquid crystal-based actuators with structural color changes and the potential applications of these structural color actuators in soft robotic devices are reviewed.
Externí odkaz:
https://doaj.org/article/bc9e291c0a234fbaa22ff77c134e48d3
Autor:
Miriam Butler, Britt M.T. Vervoort, Dorette S. van Ingen Schenau, Lieneke Jongeneel, Jordy C.G. van der Zwet, René Marke, Jules P.P. Meijerink, Blanca Scheijen, Laurens T. van der Meer, Frank N. van Leeuwen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Although long-term survival in pediatric acute lymphoblastic leukemia (ALL) currently exceeds 90%, some subgroups, defined by specific genomic aberrations, respond poorly to treatment. We previously reported that leukemias harboring deletions or muta
Externí odkaz:
https://doaj.org/article/bd62010cd4ac4cb38d96197bfa9e66ae
Publikováno v:
Crystals, Vol 12, Iss 11, p 1614 (2022)
Cholesteric liquid crystal oligomers and polymers are promising materials for creating materials and devices with stimuli-responsive structural color, and the cholesteric to smectic pre-transition effect is of particular interest as it leads to a str
Externí odkaz:
https://doaj.org/article/9854b92638324c2fa55ffb67435f5510
Autor:
Weixin Zhang, Arne A. F. Froyen, Albertus P. H. J. Schenning, Guofu Zhou, Michael G. Debije, Laurens T. de Haan
Publikováno v:
Advanced Photonics Research, Vol 2, Iss 7, Pp n/a-n/a (2021)
Cholesteric liquid crystals (CLCs) are a major class of photonic materials that display selective reflection properties arising from their helical ordering. The temperature response of CLCs, comprising dynamic reflection color changes upon variation
Externí odkaz:
https://doaj.org/article/9d3423e305ed4cef98b7a524c75daa2d
We construct a convergent family of outer approximations for the problem of optimizing polynomial functions over convex bodies subject to polynomial constraints. This is achieved by generalizing the polarization hierarchy, which has previously been i
Externí odkaz:
http://arxiv.org/abs/2406.09506
Publikováno v:
Phys. Rev. A 110 (2), 022225 (2024)
While there exist theories that have states "more strongly entangled" than quantum theory, in the sense that they show CHSH values above Tsirelson's bound, all known examples of such theories have a strictly smaller set of measurements. Therefore, in
Externí odkaz:
http://arxiv.org/abs/2405.13819
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3475-3482 (2017)
Externí odkaz:
https://doaj.org/article/4af1ef9bbd194760bb402d8ab2d87a00