Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laurens J. Lambert"'
Autor:
Jason M. Schenkel, Prajan Divakar, Alex M. Jaeger, Ana P. Garcia, Peter M. K. Westcott, Tyler Hether, Zackery A. Ely, Roderick T. Bronson, Laurens J. Lambert, Jason Reeves, William A. Freed-Pastor, Devan Phillips, Vikram Deshpande, Arjun Bhutkar, Kim L. Mercer, Ömer H. Yilmaz, Tyler Jacks, George Eng, Lin Lin, William L. Hwang, Nimisha B. Pattada, Aviv Regev, Toni Delorey, William M. Rideout
Publikováno v:
Cancer Cell
Summary The CD155/TIGIT axis can be co-opted during immune evasion in chronic viral infections and cancer. Pancreatic adenocarcinoma (PDAC) is a highly lethal malignancy, and immune-based strategies to combat this disease have been largely unsuccessf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b53f9987c16263228fdea161ccfed14
https://europepmc.org/articles/PMC8511341/
https://europepmc.org/articles/PMC8511341/
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82110 (2013)
During B cell activation, the DNA lesions that initiate somatic hypermutation and class switch recombination are introduced by activation-induced cytidine deaminase (AID). AID is a highly mutagenic protein that is maintained in the cytoplasm at stead
Externí odkaz:
https://doaj.org/article/ad401a9f4b394d67ac9c6b8e49564fd1
Autor:
Aviv Regev, Vikram Deshpande, Nimisha B. Pattada, William L. Hwang, Roderick T. Bronson, Jason M. Schenkel, William M. Rideout, Zackery A. Ely, Kim L. Mercer, William A. Freed-Pastor, Toni Delorey, Ana P. Garcia, Peter M. K. Westcott, Tyler Jacks, Laurens J. Lambert, George Eng, Arjun Bhutkar, Devan Phillips, Ömer H. Yilmaz, Lin Lin
Publikováno v:
SSRN Electronic Journal.
The CD155/TIGIT axis can be co-opted during immune evasion in chronic viral infections and cancer. Pancreatic adenocarcinoma (PDAC) is a highly lethal malignancy, and immune-based strategies to combat this disease have been largely unsuccessful to da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f34a2acc42a8054822b73a53ad148fb
https://doi.org/10.2139/ssrn.3753805
https://doi.org/10.2139/ssrn.3753805
Autor:
Nimisha B. Pattada, Laurens J. Lambert, Tyler Jacks, Alex M. Jaeger, George Eng, Kim L. Mercer, Zackery A. Ely, William A. Freed-Pastor, William L. Hwang, Arjun Bhutkar
Publikováno v:
Cancer Research. 81:PO-063
The CD155/TIGIT axis can be co-opted during immune evasion in chronic viral infections and cancer. While insights regarding mechanisms of immune escape have fueled tremendous clinical successes in a broad range of tumor types, microsatellite-stable p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265a9585b79f1aea286157db181ca177
https://doi.org/10.1158/1538-7445.panca21-po-063
https://doi.org/10.1158/1538-7445.panca21-po-063
Autor:
Enrique Amaya, Imad M. Awan, Hugo J. Bellen, Alessandro Bertero, David Brindley, Stephanie Brown, Eleanor Jane Budge, Eleni Chantzoura, John Collin, Amanda S. Coutts, Karel Dorey, Jefte M. Drijvers, Tomasz Gwozdz, Gregory A. Hawkins, Shoko Ishibashi, Tyler Jacks, Mehdi Jalali, Morteza Jalali, Sonali Joshi, Keisuke Kaji, Nicholas B. La Thangue, Laurens J. Lambert, Robert Lea, Martyna Lukoseviciute, Paul Martin, Mandar D. Muzumdar, Frederick D. Park, Cory A. Perugino, Adam Pettitt, David Pettitt, Shiv Pillai, Tannishtha Reya, William M. Rideout, MacKenna Roberts, Ian M. Rosenberg, Francesca Y.L. Saldanha, Roman Sasik, Charis-P. Segeritz, Semira Sheikh, James Smith, Ludovic Vallier, Michael F. Wangler, Dihua Yu, Justyna Zaborowska
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d10cd44acceecb1af07e50a4bf1145b
https://doi.org/10.1016/b978-0-12-803077-6.00024-2
https://doi.org/10.1016/b978-0-12-803077-6.00024-2
The mouse has long contributed to our understanding of mammalian physiology and disease. Owing to its short life cycle, fecundity, and amenability to genetic manipulation, the mouse is a powerful tool for modeling human disease. This chapter discusse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29060e221a69300df1eb931a3f4c4281
https://doi.org/10.1016/b978-0-12-803077-6.00014-x
https://doi.org/10.1016/b978-0-12-803077-6.00014-x
Autor:
Tyler Jacks, George Eng, William A. Freed-Pastor, Laurens J. Lambert, Ömer H. Yilmaz, Ana P. Garcia
Publikováno v:
Cancer Research. 79:PR14-PR14
Pancreatic adenocarcinoma (PDAC) carries a dismal prognosis and efforts to harness immune-based therapies are in high demand. Using retrograde pancreatic duct instillation of lentiviral particles, we have established and characterized a preclinical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfb73f53513adf733d5c2d1de15e9884
https://doi.org/10.1158/1538-7445.panca19-pr14
https://doi.org/10.1158/1538-7445.panca19-pr14
Autor:
Eugene Drokhlyansky, Orr Ashenberg, Debora Ciprani, Nicholas Van Wittenberghe, Theodore S. Hong, Carlos Fernandez-del Castillo, Michael S. Cuoco, Karthik A. Jagadeesh, Danielle Dionne, Tyler Jacks, Clifton Rodriguez, George Eng, Andrew S. Liss, Andrew J. Aguirre, William L. Hwang, Alexander M. Tsankov, Mari Mino-Kenudson, Orit Rozenblatt-Rosen, Aviv Regev, Caroline B. M. Porter, Julia Waldman, Jason M. Schenkel, William A. Freed-Pastor, Laurens J. Lambert, Connor Lambden
Publikováno v:
Cancer Research. 79:A22-A22
Objective: Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease as existing molecular subtypes are insufficient and do not currently inform clinical decisions. Rare cell types, including those responsible for resistance, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc5d5c9a05bf06d6e3ce90654d9862b
https://doi.org/10.1158/1538-7445.panca19-a22
https://doi.org/10.1158/1538-7445.panca19-a22
Publikováno v:
Gynecologic Oncology, 137, 335-342
Gynecologic Oncology, 137, 2, pp. 335-342
Gynecologic Oncology, 137, 2, pp. 335-342
Item does not contain fulltext Ovarian cancer is a devastating disease with a high relapse rate. Due to a mostly asymptomatic early stage and lack of early diagnostic tools, the disease is usually diagnosed in a late stage. Surgery and chemotherapy w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ac16c576b7ff931e00846efd57bf69
http://hdl.handle.net/2066/154726
http://hdl.handle.net/2066/154726