Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Laurence von Kalm"'
Publikováno v:
Medical Sciences, Vol 5, Iss 4, p 27 (2017)
Increased polyamine biosynthesis activity and an active polyamine transport system are characteristics of many cancer cell lines and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by difluorome
Externí odkaz:
https://doaj.org/article/905b98061f6742888b47310f8374de33
Autor:
Katherine Taylor, Kurt Kleinhesselink, Michael D George, Rachel Morgan, Tangi Smallwood, Ann S Hammonds, Patrick M Fuller, Perot Saelao, Jeff Alley, Allen G Gibbs, Deborah K Hoshizaki, Laurence von Kalm, Charles A Fuller, Kathleen M Beckingham, Deborah A Kimbrell
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86485 (2014)
Space travel presents unlimited opportunities for exploration and discovery, but requires better understanding of the biological consequences of long-term exposure to spaceflight. Immune function in particular is relevant for space travel. Human immu
Externí odkaz:
https://doaj.org/article/0532e9057d4d4690a966fbe263800474
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/3ebdc0f8afdb4d99a546e8c33a737277
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51126 (2012)
Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkeph
Externí odkaz:
https://doaj.org/article/0ad20e5c378749868d7f49413d00719a
Autor:
Laurence von Kalm, Corey Seavey
Publikováno v:
Cancer Research. 83:2461-2461
The motuporamines are a promising class of anti-metastatic compounds. Dihydromotuporamine C (Motu33) has been shown to activate the small GTPase RhoA, however, little is known about subsequent downstream events leading to cell migration inhibition. I
Publikováno v:
The FASEB Journal. 33
Generation of a Difluoromethylornithine (DFMO) Resistant Cell Line in a Polyamine Depletion Strategy
Publikováno v:
The FASEB Journal. 33
Autor:
David R. Brown, Laurence von Kalm
Publikováno v:
The FASEB Journal. 33
Publikováno v:
The FASEB Journal. 33
Autor:
Laurence von Kalm, Dean C. Sayle, Ankur Gupta, Rameech McCormack, Sudipta Seal, Soumen Das, Amit Kumar, Thi X. T. Sayle, Talib Dosani, Janet M. Dowding, William T. Self
Publikováno v:
ACS Nano. 7:4855-4868
The study of the chemical and biological properties of CeO2 NPs (CNPs) has expanded recently due to its therapeutic potential, and the methods used to synthesize these materials are diverse. Moreover, conflicting reports exists regarding the toxicity