Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Laurence de Nijs"'
Autor:
Katherine Bassil, Anthi C. Krontira, Thomas Leroy, Alana I.H. Escoto, Clara Snijders, Cameron D. Pernia, R. Jeroen Pasterkamp, Laurence de Nijs, Daniel van den Hove, Gunter Kenis, Marco P. Boks, Krishna Vadodaria, Nikolaos P. Daskalakis, Elisabeth B. Binder, Bart P.F. Rutten
Publikováno v:
Neurobiology of Stress, Vol 23, Iss , Pp 100530- (2023)
Hypothalamic-pituitary adrenal (HPA)axis dysregulation has long been implicated in stress-related disorders such as major depression and post-traumatic stress disorder. Glucocorticoids (GCs) are released from the adrenal glands as a result of HPA-axi
Externí odkaz:
https://doaj.org/article/4a6b05cc3b3242c0859374839792ad82
Autor:
Katherine Bassil, Laurence De Nijs, Bart P. F. Rutten, Daniel L. A. Van Den Hove, Gunter Kenis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In the last decade, in vitro models has been attracting a great deal of attention for the investigation of a number of mechanisms underlying neurological and mental disorders, including stress-related disorders, for which human brain material has rar
Externí odkaz:
https://doaj.org/article/10ff6046eb7d457bb0e75404436d1060
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5238 (2023)
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling condition resulting in a reduced quality of life and increased economic burden. The disorder is directly related to exposure to a traumatic event, e.g., a real or threa
Externí odkaz:
https://doaj.org/article/f410924ddd694fbca82f587af3af147a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10743 (2021)
Exposure to trauma is one of the most important and prevalent risk factors for mental and physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide variety of mental and physical symptoms. However, people differ strikin
Externí odkaz:
https://doaj.org/article/d1d1eae91f1d471c942813628fb3f5ca
Autor:
Clara Snijders, Julian Krauskopf, Ehsan Pishva, Lars Eijssen, Barbie Machiels, Jos Kleinjans, Gunter Kenis, Daniel van den Hove, Myeong Ok Kim, Marco P. M. Boks, Christiaan H. Vinkers, Eric Vermetten, Elbert Geuze, Bart P. F. Rutten, Laurence de Nijs
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Posttraumatic stress disorder (PTSD) is a psychiatric disorder that can develop upon exposure to a traumatic event. While most people are able to recover promptly, others are at increased risk of developing PTSD. However, the exact underlying biologi
Externí odkaz:
https://doaj.org/article/13fcad548d4644d381963e68ca7c711d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Juvenile myoclonic epilepsy (JME), a lifelong disorder that starts during adolescence, is the most common of genetic generalized epilepsy syndromes. JME is characterized by awakening myoclonic jerks and myoclonic-tonic-clonic (m-t-c) grand mal convul
Externí odkaz:
https://doaj.org/article/6cafc5c2679a4c95a646216250a0815e
Autor:
Clara Snijders, Lotta-Katrin Pries, Noemi Sgammeglia, Ghazi Al Jowf, Nagy A. Youssef, Laurence de Nijs, Sinan Guloksuz, Bart P. F. Rutten
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Given the high prevalence of stress-related mental disorders, their impact on person, family, and society and the paucity of treatment options for most of these disorders, there is currently a pressing need for innovative approaches to deal with thes
Externí odkaz:
https://doaj.org/article/02806d22d12241e9afedba8e8f8822cc
Autor:
Gerry Nganou, Carla G. Silva, Ivan Gladwyn-Ng, Dominique Engel, Bernard Coumans, Antonio V. Delgado-Escueta, Miyabi Tanaka, Laurent Nguyen, Thierry Grisar, Laurence de Nijs, Bernard Lakaye
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The building of the brain is a multistep process that requires the coordinate expression of thousands of genes and an intense nucleocytoplasmic transport of RNA and proteins. This transport is mediated by karyopherins that comprise importins and expo
Externí odkaz:
https://doaj.org/article/edb77971962f4dd288a9318616e0eec4
Autor:
Ghazi I. Al Jowf, Ziyad T. Ahmed, Ning An, Rick A. Reijnders, Elena Ambrosino, Bart P. F. Rutten, Laurence de Nijs, Lars M. T. Eijssen
Publikováno v:
International Journal of Environmental Research and Public Health. 19(11)
Trauma exposure is one of the most important and prevalent risk factors for mental and physical ill-health. Prolonged or excessive stress exposure increases the risk of a wide variety of mental and physical symptoms, resulting in a condition known as
Autor:
Jos C. S. Kleinjans, Meghan E. Jones, Marco P. Boks, Kerry J. Ressler, Eric Vermetten, Courtney A. Miller, Julian Krauskopf, Torsten Klengel, Laurence de Nijs, Christiaan H. Vinkers, Sarah E. Jamieson, Nadine F. Joseph, Gavin Rumbaugh, Stephanie E. Sillivan, Elbert Geuze, Clara Snijders, Sabina Berretta, Bart P. F. Rutten
Publikováno v:
Molecular Psychiatry, 25(5), 965-976. Nature Publishing Group
Sillivan, S E, Jamieson, S, de Nijs, L, Jones, M, Snijders, C, Klengel, T, Joseph, N F, Krauskopf, J, Kleinjans, J, Vinkers, C H, Boks, M P M, Geuze, E, Vermetten, E, Berretta, S, Ressler, K J, Rutten, B P F, Rumbaugh, G & Miller, C A 2020, ' MicroRNA regulation of persistent stress-enhanced memory ', Molecular Psychiatry, vol. 25, no. 5, pp. 965-976 . https://doi.org/10.1038/s41380-019-0432-2
Molecular Psychiatry, 25(5), 965-976. NATURE PUBLISHING GROUP
Web of Science
Molecular psychiatry
Sillivan, S E, Jamieson, S, de Nijs, L, Jones, M, Snijders, C, Klengel, T, Joseph, N F, Krauskopf, J, Kleinjans, J, Vinkers, C H, Boks, M P M, Geuze, E, Vermetten, E, Berretta, S, Ressler, K J, Rutten, B P F, Rumbaugh, G & Miller, C A 2020, ' MicroRNA regulation of persistent stress-enhanced memory ', Molecular Psychiatry, vol. 25, no. 5, pp. 965-976 . https://doi.org/10.1038/s41380-019-0432-2
Molecular Psychiatry, 25(5), 965-976. NATURE PUBLISHING GROUP
Web of Science
Molecular psychiatry
Disruption of persistent, stress-associated memories is relevant for treating posttraumatic stress disorder (PTSD) and related syndromes, which develop in a subset of individuals following a traumatic event. We previously developed a stress-enhanced