Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Laurence Van Melderen"'
Autor:
Laurence Van Melderen
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT In a recent article, Balaban and colleagues developed the iTDtest allowing characterization of the type of interactions between different antibiotics at bactericidal concentrations (J.-F. Liu et al., mBio 13:e00004-22, 2022). This visual and
Externí odkaz:
https://doaj.org/article/779d5b1d74f44181aa6826b274e483f4
Autor:
Dukas Jurėnas, Nathan Fraikin, Frédéric Goormaghtigh, Pieter De Bruyn, Alexandra Vandervelde, Safia Zedek, Thomas Jové, Daniel Charlier, Remy Loris, Laurence Van Melderen
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Type II toxin-antitoxin (TA) systems are classically composed of two genes that encode a toxic protein and a cognate antitoxin protein. Both genes are organized in an operon whose expression is autoregulated at the level of transcription by
Externí odkaz:
https://doaj.org/article/95bd3afb4724476fbc885a2c3c681259
Autor:
Juan Carlos Fragoso-Jiménez, Jonathan Baert, Thai Minh Nguyen, Wenzheng Liu, Hosni Sassi, Frédéric Goormaghtigh, Laurence Van Melderen, Paul Gaytán, Georgina Hernández-Chávez, Alfredo Martinez, Frank Delvigne, Guillermo Gosset
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Escherichia coli W3110 and a group of six isogenic derivatives, each displaying distinct specific rates of glucose consumption were characterized to determine levels of GFP production and population heterogeneity. These strains ha
Externí odkaz:
https://doaj.org/article/f83509b60b9c4b75922ba6fc8b010eb1
Autor:
Stéphane Pont, Nathan Fraikin, Yvan Caspar, Laurence Van Melderen, Ina Attrée, François Cretin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1008893 (2020)
Bacterial bloodstream infections (BSI) are a major health concern and can cause up to 40% mortality. Pseudomonas aeruginosa BSI is often of nosocomial origin and is associated with a particularly poor prognosis. The mechanism of bacterial persistence
Externí odkaz:
https://doaj.org/article/2a0dac12c22040f9b9ede7583e840c65
Autor:
Gipsi Lima-Mendez, Danillo Oliveira Alvarenga, Karen Ross, Bernard Hallet, Laurence Van Melderen, Alessandro M. Varani, Michael Chandler
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is arguably one of the most widespread transposon families. Members carry a large range of pass
Externí odkaz:
https://doaj.org/article/c0e047765c084cb486222d54c62a97f6
Autor:
Dukas Jurėnas, Laurence Van Melderen
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Type II Toxin–antitoxin (TA) modules are bacterial operons that encode a toxic protein and its antidote, which form a self-regulating genetic system. Antitoxins put a halter on toxins in many ways that distinguish different types of TA modules. In
Externí odkaz:
https://doaj.org/article/4091bac861794bcc87475908a5210452
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Toxin-antitoxin (TA) systems are broadly distributed modules whose biological roles remain mostly unknown. The mqsRA system is a noncanonical TA system in which the toxin and antitoxins genes are organized in operon but with the particularit
Externí odkaz:
https://doaj.org/article/70517d750ee24d10acdc10ae690ef001
Autor:
Heleen Van Acker, Aurélie Crabbé, Dukas Jurėnas, Lisa Ostyn, Andrea Sass, Simon Daled, Maarten Dhaenens, Dieter Deforce, Eline Teirlinck, Herlinde De Keersmaecker, Kevin Braeckmans, Laurence Van Melderen, Tom Coenye
Publikováno v:
Biofilm, Vol 1, Iss , Pp - (2019)
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical
Externí odkaz:
https://doaj.org/article/1813f374099d49bba0e33d369f424955
Autor:
Frédéric Goormaghtigh, Nathan Fraikin, Marta Putrinš, Vasili Hauryliuk, Abel Garcia-Pino, Klas Udekwu, Tanel Tenson, Niilo Kaldalu, Laurence Van Melderen
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
Externí odkaz:
https://doaj.org/article/e37eda3a367e4dee850553414bcfc84c
Autor:
Frédéric Goormaghtigh, Nathan Fraikin, Marta Putrinš, Thibaut Hallaert, Vasili Hauryliuk, Abel Garcia-Pino, Andreas Sjödin, Sergo Kasvandik, Klas Udekwu, Tanel Tenson, Niilo Kaldalu, Laurence Van Melderen
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Persistence is a reversible and low-frequency phenomenon allowing a subpopulation of a clonal bacterial population to survive antibiotic treatments. Upon removal of the antibiotic, persister cells resume growth and give rise to viable progen
Externí odkaz:
https://doaj.org/article/2a24a6e8c67446f98d3a38d560a784c5