Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laurence Turka"'
Autor:
Sivan Elloul, Anne-Sophie Dugast, Shannon McArdel, Enping Hong, Maegan Hoover, Laurence Turka, Zafira Castano, Arjun Reddy Bollampalli, Shannon Leonard, Ryan Pepi, Alex Nanna
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/305ceefb96694077a20dee7fde51ad88
Autor:
Sivan Elloul, Anne-Sophie Dugast, Shannon McArdel, Enping Hong, Arjun Bollampalli, Maegan Hoover, Sneha Pawar, Viral Amin, Kangjian Qiao, Christopher Ta, Laurence Turka, Thomas Wickham
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/8a6fd99397684961baede2a785881b1e
Autor:
Omid Hamid, Melissa L. Johnson, Jason Luke, Richard T. Maziarz, Jamie Merchan, Emerson E. Lim, Sandip P. Patel, Geoffrey M. Kuesters, Iga Sienczylo, Gilad Gordon, Karen Campbell, Kristin Horton, Laurence Turka, Alexander I. Spira
Publikováno v:
Cancer Research. 82:CT187-CT187
Background: RTX-240 is an allogeneic cellular therapy genetically engineered to express high copy numbers of trimeric 4-1BBL and IL-15/IL-15Rα fusion proteins on the RBC surface membrane. RTX-240 is designed to activate and expand CD8+ memory T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c93b3ab45248c3100d06e12b49aa8974
https://doi.org/10.1158/1538-7445.am2022-ct187
https://doi.org/10.1158/1538-7445.am2022-ct187
Autor:
Laurence Turka
Publikováno v:
Molecular Cancer Research. 18:IA16-IA16
A number of receptors are capable of activating the PI3K pathway in T cells, most prominently the T-cell receptor for antigen (TCR), the costimulatory receptor CD28, and the interleukin 2 receptor (IL-2R). PI3K signaling is critical for the initiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913bfb48fb454b761399ac1afd3866bb
https://doi.org/10.1158/1557-3125.pi3k-mtor18-ia16
https://doi.org/10.1158/1557-3125.pi3k-mtor18-ia16
Publikováno v:
Immunological reviews. 193
Self-tolerance is maintained by several mechanisms including deletion (via apoptosis) and regulation. Acquired tolerance to allogeneic tissues and organs exploits similar strategies. One key difference between alloantigens and peptide antigens is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a977bf0a3d8a070665d9cbbbe46fb2d5
https://pubmed.ncbi.nlm.nih.gov/12752677
https://pubmed.ncbi.nlm.nih.gov/12752677
Autor:
Harlan Robins, Paolo Muraro, Sachin Malhotra, Michael Howell, Deborah Phippard, Cindy Desmarais, Alessandra de Paula Alves Sousa, Linda Griffith, Noha Lim, Richard Nash, Laurence Turka
Publikováno v:
The Journal of Immunology. 192:136.5-136.5
Autologous hematopoietic stem cell transplantation (HSCT) is commonly employed for hematologic and non-hematologic malignancies and also has been used in clinical trials for severe autoimmune diseases to “reset” the immune system and produce a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b9bfe9f52b0c67981000324e36ae047
https://doi.org/10.4049/jimmunol.192.supp.136.5
https://doi.org/10.4049/jimmunol.192.supp.136.5
Publikováno v:
The Journal of Immunology. 188:73.2-73.2
The TLR-MyD88 signaling pathway enables the innate immune system to sense inflammation and promote adaptive immune responses. Previously, we have shown that T cell intrinsic MyD88 signaling promotes T cell survival and is required for optimal respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::469dd05093093683f99f4c39b434d0be
https://doi.org/10.4049/jimmunol.188.supp.73.2
https://doi.org/10.4049/jimmunol.188.supp.73.2
Autor:
Tyler Curiel, Mark Kious, Benjamin Daniel, Pei Lin, Suzanne Thibodeaux, Ratna Vadlamudi, Margaret Wierman, Laurence Turka, Ruan Zhang, Arlene Sharpe, Loise Francisco, Sun Lishi, Srilakshmi Pandaswara, Rajeshwar Tekmal, Vincent Hurez
Publikováno v:
The Journal of Immunology. 188:123.50-123.50
CD4+CD25hi regulatory T cells (Tregs) mediate peripheral tolerance and defend against autoimmunity. Among immune sexual dimorphisms, autoimmunity is more common in females but underlying mechanism(s) are poorly understood. We show that B7-H1 signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a3c5e6a0aafa80fbe3f2a1f97d1962
https://doi.org/10.4049/jimmunol.188.supp.123.50
https://doi.org/10.4049/jimmunol.188.supp.123.50