Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laurence Périn"'
Publikováno v:
JCRPE, Vol 11, Iss 3, Pp 253-261 (2019)
Objective:IGF1 concentration is the most widely used parameter for the monitoring and therapeutic adaptation of recombinant human growth hormone (rGH) treatment. However, more than half the variation of the therapeutic response is accounted for by va
Externí odkaz:
https://doaj.org/article/9e466cfe6a9441a0a2a9a79f37ebd9b0
Autor:
Lyvianne Decourtye, Maud Clemessy, Erik Mire, Tatiana Ledent, Laurence Périn, Iain C Robinson, Yves Le Bouc, Laurent Kappeler
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193196 (2018)
Nutrition plays a critical role in programming and shaping linear growth during early postnatal life through direct action on the development of the neuroendocrine somatotropic (GH/IGF-1) axis. IGF-1 is a key factor in modulating the programming of l
Externí odkaz:
https://doaj.org/article/b327a35da5314a11bd2b35051f4cb17c
Autor:
Laurent Kappeler, Carlos De Magalhaes Filho, Joëlle Dupont, Patricia Leneuve, Pascale Cervera, Laurence Périn, Catherine Loudes, Annick Blaise, Rüdiger Klein, Jacques Epelbaum, Yves Le Bouc, Martin Holzenberger
Publikováno v:
PLoS Biology, Vol 6, Iss 10, p e254 (2008)
Mutations that decrease insulin-like growth factor (IGF) and growth hormone signaling limit body size and prolong lifespan in mice. In vertebrates, these somatotropic hormones are controlled by the neuroendocrine brain. Hormone-like regulations disco
Externí odkaz:
https://doaj.org/article/0c8d24f4a14e43c79b451ce8c5aeea14
Autor:
Gwenaëlle Arnault-Ouary, N. Bourcigaux, Bernard Charbonnel, Yves Le Bouc, R. Christol, Laurence Périn
Publikováno v:
Clinical Therapeutics. 27:246-251
Background: Non-islet cell tumor hypoglycemia(NICTH) is a rare cause of recurrent hypoglycemia. It has been associated with the tumoral overproduction of high-molecular-weight insulin-like growth factor (IGF)-2 (“big IGF-2”). Big IGF-2 suppresses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0977930bd7d568b5596ec68b5e5e38
https://doi.org/10.1016/j.clinthera.2005.02.004
https://doi.org/10.1016/j.clinthera.2005.02.004
Autor:
Aurelie Pham, Delphine Mitanchez, Anne Forhan, Laurence Perin, Yves Le Bouc, Frederic Brioude, Marie-Laure Sobrier, Barbara Heude, Irene Netchine
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Detecting SGA (small for gestational age) during pregnancy improves the fetal and neonatal prognosis. To date, there is no valid antenatal biomarker of SGA used in clinical practice. Maternal circulating DLK1 (delta-like non-canonical notch ligand 1)
Externí odkaz:
https://doaj.org/article/54434e9b12d244b4afc959af61b29a70
Autor:
Fanny Mochel, Perrine Charles, François Seguin, Julie Barritault, Christiane Coussieu, Laurence Perin, Yves Le Bouc, Christiane Gervais, Guislaine Carcelain, Anne Vassault, Josué Feingold, Daniel Rabier, Alexandra Durr
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e647 (2007)
Huntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment. The pathogenic mechanisms underlying HD has not been elucidated, but weight loss, associated with chorea and cognitive decline, is a characteristic feature of
Externí odkaz:
https://doaj.org/article/4a446a7ac0c542b48beeeffd9459f875