Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Laurence Orchard"'
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Akademický článek
Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn’s-like Lymphoid Reaction
Autor: Viktoriya B. Boncheva, Michael Linnebacher, Said Kdimati, Hannah Draper, Laurence Orchard, Ken I. Mills, Gerald O’Sullivan, Mark Tangney, Barbara-ann Guinn
Publikováno v: Biomolecules, Vol 12, Iss 8, p 1058 (2022)
A Crohn’s-like lymphoid reaction (CLR) is observed in about 15% of colorectal cancer (CRC) patients and is associated with favourable outcomes. To identify the immune targets recognised by CRC CLR patient sera, we immunoscreened a testes cDNA libra
Externí odkaz: https://doaj.org/article/c364a480018545e4a16d08b5ea91e6f6
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4
Vitamin-D levels and intensive care unit outcomes of a cohort of critically ill COVID-19 patients
Autor: Dushianthan Ahilanandan, Kordo Saeed, Myra Nasim-Mohi, Laurence Orchard, Matthew Baldry, Michael P.W. Grocott, Chantelle Monck
Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM). 59:1155-1163
Objectives The pattern of global COVID-19 has caused many to propose a possible link between susceptibility, severity and vitamin-D levels. Vitamin-D has known immune modulatory effects and deficiency has been linked to increased severity of viral in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb23e8b7f32934fe3cdf4e32a1784e1b
https://doi.org/10.1515/cclm-2020-1567
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Serum profiling identifies ibrutinib as a treatment option for young adults with B-cell acute lymphoblastic leukaemia
Autor: Barbara-Ann Guinn, Ken I. Mills, Laurence Orchard, Stephanie Bonney, Viggo Van Tendeloo, Kim Orchard, Leah Cooksey, Matthew Coutinho, Stephanie Jordaens
Publikováno v: Jordaens, S, Cooksey, L, Bonney, S, Orchard, L, Coutinho, M, Van Tendeloo, V, Mills, K I, Orchard, K & Guinn, B-A 2020, ' Serum profiling identifies ibrutinib as a treatment option for young adults with B-cell acute lymphoblastic leukaemia ', British Journal of Haematology, vol. 189, no. 3, pp. 500-512 . https://doi.org/10.1111/bjh.16407
British journal of haematology
Acute lymphoblastic leukaemia (ALL) is a haematological malignancy that is characterized by the uncontrolled proliferation of immature lymphocytes. 80% of cases occur in children where ALL is well understood and treated. However it has a devastating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fe1442d05a82455e5ad9d9ba9bf17b
https://pure.qub.ac.uk/en/publications/serum-profiling-identifies-ibrutinib-as-a-treatment-option-for-young-adults-with-bcell-acute-lymphoblastic-leukaemia(d7fa9a66-a865-453b-a5ee-211e923e3daf).html
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Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia
Autor: Payalben Savaliya, Evelien Smits, Ken I. Mills, Alison H. Banham, Laurie Freire Boullosa, Cindy Lee, Stephanie Bonney, Barbara-Ann Guinn, Hannah Wickenden, Laurence Orchard, Kim Orchard
Publikováno v: Oncotarget
Boullosa, L F, Savaliya, P, Bonney, S, Orchard, L, Wickenden, H, Lee, C, Smits, E, Banham, A H, Mills, K I, Orchard, K & Guinn, B A 2017, ' Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia ', Oncotarget, vol. 9, no. 3, pp. 3853-3866 . https://doi.org/10.18632/oncotarget.23380
B-cell acute lymphoblastic leukemia (B-ALL) is a rare heterogeneous disease characterized by a block in lymphoid differentiation and a rapid clonal expansion of immature, non-functioning B cells. Adult B-ALL patients have a poor prognosis with less t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe2e8206975354ad36156e7d1c63dc0
http://europepmc.org/articles/PMC5790505
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PO-408 New targets for the immunotherapy of adult B-cell acute lymphocytic leukaemia
Autor: Laurence Orchard, Kim Orchard, Barbara-Ann Guinn, P. Savaliya, Ken I. Mills, Leah Cooksey, Evelien Ljm Smits, Stephanie Bonney, L. Freire Boullosa
Publikováno v: ESMO Open. 3:A389-A390
Introduction B-cell acute lymphocytic leukaemia (B-ALL) is a rare heterogeneous disease characterised by excess lymphoblasts of the B-lineage in the bone marrow. The most effective treatment to date is allogeneic stem cell transplant which can improv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc8963d1bbe7f5389a7af93d0c74f3cd
https://doi.org/10.1136/esmoopen-2018-eacr25.919
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Emergency video-assisted thoracoscopic surgery for haemopneumothorax and diaphragm repair after stabbing, performed through pre-existing wounds
Autor: Laurence Orchard, Aman S. Coonar
Publikováno v: Interactive cardiovascular and thoracic surgery. 24(6)
Video of video-assisted thoracoscopic surgery (VATS) on a 16-year old who had been stabbed. The knife penetrated the diaphragm, lung and intercostal pedicle causing a haemopneumothorax. A chest drain was inserted by the trauma team. VATS was performe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf03f96bdeaa0f8bffd01a06f11ef83a
https://pubmed.ncbi.nlm.nih.gov/28369494
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