Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laurence M. Levasseur"'
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 35:270-278
In preparing for the routine use of the ubiquitous in vitro cell growth inhibition assay for the study of anticancer agents, we characterized the statistical properties of the assay and found some surprising results. Parabolic well-to-well cell growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d1a27c23ea3b3b0aa279a5bbc8c259
https://doi.org/10.1007/s11626-999-0071-z
https://doi.org/10.1007/s11626-999-0071-z
Publikováno v:
Pharmaceutical Research. 16:1894-1897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ae867f14cac1321c16e7b74843f38c0
https://doi.org/10.1023/a:1011967813140
https://doi.org/10.1023/a:1011967813140
Autor:
William Couet, Serge Bouquet, William R. Greco, Pascal Faury, Laurence M. Levasseur, Annie Delon
Publikováno v:
Pharmaceutical Research. 15:1069-1076
Purpose. A new mathematical approach was developed to quantify convulsant interaction between pefloxacin and theophylline in rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b9f16c727825f651c64bdb08b85256a
https://doi.org/10.1023/a:1011938429379
https://doi.org/10.1023/a:1011938429379
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 26:717-733
Modeling of nonlinear pharmacodynamic (PD) relationships necessitates the utilization of a weighting function in order to compensate for the heteroscedasticity. The structure of the variance was studied for concentration-effect data generated in an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece20e73a7ec1bebcdfdfbeefe71a474
https://doi.org/10.1023/a:1020755124451
https://doi.org/10.1023/a:1020755124451
Autor:
James Nezamis, Lorinda Simms, Doris K. Robbins, Kevin M. Koch, Laurence M. Levasseur, Doreen L. D'Souza
Publikováno v:
The Journal of Clinical Pharmacology. 41:452-454
Lotronex (alosetron hydrochloride) is a 5-HT3 receptor antagonist indicated for the treatment of irritable bowel syndrome (IBS) in females whose predominant bowel habit is diarrhea. Alosetron is extensively metabolized by multiple cytochrome P450 (CY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f65e3925502e9488e7d9d263e7ccbb2
https://doi.org/10.1177/00912700122010168
https://doi.org/10.1177/00912700122010168
Publikováno v:
Dose-Response, Vol 1 (2003)
Many drug concentration-effect relationships are described by nonlinear sigmoid models. The 4-parameter Hill model, which belongs to this class, is commonly used. An experimental design is essential to accurately estimate the parameters of the model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1647e36f2f28003d47a170d95f09df0a
https://doaj.org/article/4a984e09216b4974ad910752c8a6c9c9
https://doaj.org/article/4a984e09216b4974ad910752c8a6c9c9
Publikováno v:
Cancer chemotherapy and pharmacology. 40(6)
Purpose: The combination of paclitaxel (PTX) and cisplatin (DDP) shows good clinical efficacy against ovarian cancer. In order to examine the potential cellular basis for this, and provide leads as to how to optimize the combination, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0ee886a5ca3c33de015e72d5e989e
https://pubmed.ncbi.nlm.nih.gov/9332464
https://pubmed.ncbi.nlm.nih.gov/9332464
The Search for Cytotoxic Synergy Between Anticancer Agents: a Case of Dorothy and the Ruby Slippers?
Publikováno v:
JNCI: Journal of the National Cancer Institute. 88:699-700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e3f145f71c71112a57b0a25aefc1c1b
https://doi.org/10.1093/jnci/88.11.699
https://doi.org/10.1093/jnci/88.11.699