Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Laurence M, Brill"'
Autor:
Shu-ichi Okamoto, Olga Prikhodko, Juan Pina-Crespo, Anthony Adame, Scott R. McKercher, Laurence M. Brill, Nobuki Nakanishi, Chang-ki Oh, Tomohiro Nakamura, Eliezer Masliah, Stuart A. Lipton
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 390-397 (2019)
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety a
Externí odkaz:
https://doaj.org/article/a572bd40338d4b15b09c31e72f6e65cb
Autor:
Ilyas Singec, Andrew M. Crain, Junjie Hou, Brian T.D. Tobe, Maria Talantova, Alicia A. Winquist, Kutbuddin S. Doctor, Jennifer Choy, Xiayu Huang, Esther La Monaca, David M. Horn, Dieter A. Wolf, Stuart A. Lipton, Gustavo J. Gutierrez, Laurence M. Brill, Evan Y. Snyder
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Controlled differentiation of human embryonic stem cells (hESCs) can be utilized for precise analysis of cell type identities during early development. We established a highly efficient neural induction strategy and an improved analytical platform, a
Externí odkaz:
https://doaj.org/article/03e02bec095e4ecea0312b9f57adc932
Autor:
Philip R. McQuary, Chen-Yu Liao, Jessica T. Chang, Caroline Kumsta, Xingyu She, Andrew Davis, Chu-Chiao Chu, Sara Gelino, Rafael L. Gomez-Amaro, Michael Petrascheck, Laurence M. Brill, Warren C. Ladiges, Brian K. Kennedy, Malene Hansen
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2059-2067 (2016)
Deficiency of S6 kinase (S6K) extends the lifespan of multiple species, but the underlying mechanisms are unclear. To discover potential effectors of S6K-mediated longevity, we performed a proteomics analysis of long-lived rsks-1/S6K C. elegans mutan
Externí odkaz:
https://doaj.org/article/29b2484ea09e4ed5ac62471d7032b3bc
Publikováno v:
F1000Research, Vol 3 (2014)
NKX3.1 is a homeobox transcription factor whose function as a prostate tumor suppressor remains insufficiently understood because neither the transcriptional program governed by NKX3.1, nor its interacting proteins have been fully revealed. Using aff
Externí odkaz:
https://doaj.org/article/94b22a5e1da2442b84125740219f56ef
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 17, Iss 1, Pp 16-26 (2004)
Legume lectins have been proposed to have important symbiotic roles during Rhizobium-legume symbioses. To test this hypothesis, the symbiotic responses of transgenic alfalfa plants that express a portion of the putative alfalfa lectin gene MsLEC1 or
Externí odkaz:
https://doaj.org/article/b732b248264d4ce1ac4058af3eb6f2d1
Autor:
Marzia Scortegagna, Hyungsoo Kim, Jian-Liang Li, Hang Yao, Laurence M Brill, Jaeseok Han, Eric Lau, David Bowtell, Gabriel Haddad, Randal J Kaufman, Ze'ev A Ronai
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004348 (2014)
The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). Yet, it is not known how UPR-signaling coordinates adaptation versus cell death. Previous studies suggested tha
Externí odkaz:
https://doaj.org/article/6ddf1d2d0fe64df59b796ae086022ff2
Autor:
April N Meyer, Kristine A Drafahl, Christopher W McAndrew, Jennifer E Gilda, Leandro H Gallo, Martin Haas, Laurence M Brill, Daniel J Donoghue
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84497 (2013)
Signaling regulated by NFκB and related transcription factors is centrally important to many inflammatory and autoimmune diseases, cancer, and stress responses. The kinase that directly regulates the canonical NFκB transcriptional pathway, Inhibito
Externí odkaz:
https://doaj.org/article/94e790c838bc4b7db7445582e2055c14
Autor:
Juan C. Piña-Crespo, Eliezer Masliah, Tomohiro Nakamura, Olga Prikhodko, Stuart A. Lipton, Chang-ki Oh, Shu-ichi Okamoto, Scott R. McKercher, Laurence M. Brill, Anthony Adame, Nobuki Nakanishi
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 127, Iss, Pp 390-397 (2019)
Neurobiology of Disease, Vol 127, Iss, Pp 390-397 (2019)
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f096d3e1599cf685a03df3eaf2da95
https://escholarship.org/uc/item/0f96239z
https://escholarship.org/uc/item/0f96239z
Autor:
Brian T. D. Tobe, Alicia M. Winquist, Laurence M. Brill, Gustavo J. Gutierrez, Andrew Crain, Stuart A. Lipton, Junjie Hou, Jennifer Choy, Kutbuddin S. Doctor, Maria Talantova, Evan Y. Snyder, Esther La Monaca, Dieter A. Wolf, Xiayu Huang, David Horn, Ilyas Singec
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Stem cell reports, vol 7, iss 3
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Stem cell reports, vol 7, iss 3
Summary Controlled differentiation of human embryonic stem cells (hESCs) can be utilized for precise analysis of cell type identities during early development. We established a highly efficient neural induction strategy and an improved analytical pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f648220803f9d96faf220f4af68fd67c
http://europepmc.org/articles/PMC5032292
http://europepmc.org/articles/PMC5032292
Autor:
Laurence M. Brill, Keith L. Wycoff
Publikováno v:
Molecular Methods in Plant Pathology ISBN: 9780203746523
This chapter reviews advances in the study of plant disease brought about by using monoclonal antibodies raised against fungi. It also reviews the use of monoclonal antibodies in plant disease research. Successful detection and quantitation of fungal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39001190227feb5afca3ac1fb92cec7
https://doi.org/10.1201/9780203746523-27
https://doi.org/10.1201/9780203746523-27