Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Laurence Levy"'
Autor:
Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background E3 ubiquitin ligases play critical roles in regulating cellular signaling pathways by inducing ubiquitylation of key components. RNF111/Arkadia is a RING E3 ubiquitin ligase that activates TGF-β signaling by inducing ubiquitylati
Externí odkaz:
https://doaj.org/article/4d59593c44454d2c8d1c621efb3821b6
Autor:
Céline Prunier, Ming-Zhu Zhang, Santosh Kumar, Laurence Levy, Olivier Ferrigno, Guri Tzivion, Azeddine Atfi
Publikováno v:
Cell Reports, Vol 10, Iss 6, Pp 883-890 (2015)
PHRF1 functions as an essential component of the TGF-β tumor suppressor pathway by triggering degradation of the homeodomain repressor factor TGIF. This leads to redistribution of cPML into the cytoplasm, where it coordinates phosphorylation and act
Externí odkaz:
https://doaj.org/article/bda8e2b5818e458e9a5639117595cce2
Autor:
Asma Ettahar, Olivier Ferrigno, Ming-Zhu Zhang, Mutsuko Ohnishi, Nathalie Ferrand, Céline Prunier, Laurence Levy, Marie-Françoise Bourgeade, Ivan Bieche, Damian G. Romero, Frédéric Colland, Azeddine Atfi
Publikováno v:
Cell Reports, Vol 4, Iss 3, Pp 530-541 (2013)
The homeodomain protein TGIF (TG-interacting factor) restricts TGF-β/Smad cytostatic signaling by interfering with the nucleocytoplasmic transit of the tumor suppressor cPML. Here, we identify PHRF1 as a ubiquitin ligase that enforces TGIF decay by
Externí odkaz:
https://doaj.org/article/7df0852ea2e145babc72f4f55e903569
Autor:
Isabelle Berthaut, Geoffroy Guignedoux, Frederique Kirsch-Noir, Vanina de Larouziere, Celia Ravel, Dora Bachir, Frédéric Galactéros, Pierre-Yves Ancel, Jean-Marie Kunstmann, Laurence Levy, Pierre Jouannet, Robert Girot, Jacqueline Mandelbaum
Publikováno v:
Haematologica, Vol 93, Iss 7 (2008)
Background Recent progress in the treatment of sickle cell disease, in particular the use of hydroxyurea, has considerably modified the prognosis of this disease. Many more patients now reach reproductive age. The objective of this study was to asses
Externí odkaz:
https://doaj.org/article/b277b1a3428e417b9e9df83e7860bc34
Autor:
Caroline S. Hill, Erik Sahai, Yigit Erker, Debipriya Das, Chris D. Madsen, Laurence Levy, Marco A. Briones-Orta
Supplementary Figure S6 PDF File - 35K, Validation of RNA-seq data by qPCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18664e2b1aa5eeca671d94e1ea1003ba
https://doi.org/10.1158/0008-5472.22399341.v1
https://doi.org/10.1158/0008-5472.22399341.v1
Autor:
Caroline S. Hill, Erik Sahai, Yigit Erker, Debipriya Das, Chris D. Madsen, Laurence Levy, Marco A. Briones-Orta
Supplementary Table S1 PDF File - 52K, Number of tumors observed in the lungs 20 and 30 days post-injection for parental NCI-H460 cells and clones NCI-H460 WT Ark 1 and NCI H460 Ark 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b38690201a7f5ae0cf12b2c513cc14d
https://doi.org/10.1158/0008-5472.22399323.v1
https://doi.org/10.1158/0008-5472.22399323.v1
Autor:
Caroline S. Hill, Erik Sahai, Yigit Erker, Debipriya Das, Chris D. Madsen, Laurence Levy, Marco A. Briones-Orta
Supplementary Legends PDF File - 120K, Legends for Supplementary Figures, Table, and Movies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf2b0a856d5f56a0e14841c5c4a9cb6
https://doi.org/10.1158/0008-5472.22399335
https://doi.org/10.1158/0008-5472.22399335
Autor:
Caroline S. Hill, Erik Sahai, Yigit Erker, Debipriya Das, Chris D. Madsen, Laurence Levy, Marco A. Briones-Orta
Supplementary Movie S1 AVI file - 1075K, GFP-labeled parental MDA-MB-231 cells were seeded on top of a layer of HUVEC cells, and images were acquired every 5 min using a Plan apochromat 20x 0.8 objective on a Zeiss LSM 780 confocal microscope. The mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700f18a97c15ac2c4730ca0aab32e059
https://doi.org/10.1158/0008-5472.22399329
https://doi.org/10.1158/0008-5472.22399329
Autor:
Marie Pierre Pirlot, Ophélie Morand, Vincent Grosjean, Thierry Letzelter, Laurence Levy Amon, Najoua Salti, Laure Élise Courtois, Céline Perrin, Julie Galmiche, Sigolène Calvat, Beatrice Leclercq, Myriam Claude
Publikováno v:
Archives des Maladies Professionnelles et de l'Environnement. 81:432-433
Le service de Sante au travail (SST) d’Orange a mene une etude ayant comme objectifs d’evaluer les pratiques et ressentis globaux lies aux pratiques de connexion des salaries cadres, de definir et de caracteriser les populations les plus connecte
Autor:
Sabrina Colasse, Tiphaine Perron, Sadek Amhaz, Isabelle Petit, Victor Laigle, Damarys Loew, Florent Dingli, Patrick Poullet, Laurence Levy, Céline Prunier, Mouna Chouchène
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, 2021, pp.100173. ⟨10.1016/j.mcpro.2021.100173⟩
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, 2021, pp.100173. ⟨10.1016/j.mcpro.2021.100173⟩
RNF111/Arkadia is an E3 ubiquitin ligase that activates the transforming growth factor-β (TGF-β) pathway by degrading transcriptional repressors SKIL/SnoN and SKI. Truncations of the RING C-terminal domain of RNF111 that abolish its E3 function and