Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Laurence Lejeune"'
Publikováno v:
Éducation permanente
Éducation permanente, 2022, N° 231 (2), pp.49-59. ⟨10.3917/edpe.231.0049⟩
Éducation permanente, 2022, N° 231 (2), pp.49-59. ⟨10.3917/edpe.231.0049⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4dc33590d642e3555cd91215f11aa10
https://hal.science/hal-04090960
https://hal.science/hal-04090960
Autor:
Ian B. Copland, Kapil Sharma, Jacques Galipeau, Peter Liu, Nicoletta Eliopoulos, Kevin Lachapelle, Duncan J. Stewart, Laurence Lejeune
Publikováno v:
Experimental Hematology. 36:93-103
CD34 is a sialomucin often expressed by cells with hemangiopoietic potential and widely serves as a surrogate marker of stem cell potential. Mesenchymal stromal cells (MSCs) also express CD34, although the functional significance of its expression re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529abb159d75ddb9ce7e29ec95d03d31
https://doi.org/10.1016/j.exphem.2007.08.032
https://doi.org/10.1016/j.exphem.2007.08.032
Autor:
Yves Durocher, Sabrina R. Perri, Louis Bisson, Daniel Martineau, Jacques Galipeau, Laurence Lejeune, Moïra François
Publikováno v:
Molecular Cancer Therapeutics. 6:441-449
Proteolytic processing of human plasminogen generates potent antiangiogenic peptides such as angiostatin. The plasminogen kringle 5 (K5) domain, which is distinct from angiostatin, possesses potent antiangiogenic properties on its own, which can be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50aa4b6357b7b8e9d49f941bb41c66df
https://doi.org/10.1158/1535-7163.mct-06-0434
https://doi.org/10.1158/1535-7163.mct-06-0434
Autor:
Borhane Annabi, Laurence Lejeune, Moïra François, Moutih Rafei, Jacques Galipeau, Jian Hui Wu
Publikováno v:
Blood. 109:2234-2242
We hypothesized that a granulocyte macrophage colony-stimulating factor (GMCSF) and interleukin 15 (IL-15) fusokine (GIFT15) would possess greater immune-stimulatory properties than their combined use. Unexpectedly, tumor cells engineered to secrete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516c0539bddaf9113bd071d5c2618c63
https://doi.org/10.1182/blood-2006-07-037473
https://doi.org/10.1182/blood-2006-07-037473
Publikováno v:
STEM CELLS. 24:2557-2565
The ease of isolation and ex vivo culture of marrow-derived stromal cells (MSCs) from adult bone marrow renders them a very promising source of adult stem cells for gene transfer and cell therapy. However, little is known about the signaling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64c6b2e860d7e98a00eba79681d399f
https://doi.org/10.1634/stemcells.2006-0209
https://doi.org/10.1634/stemcells.2006-0209
Publikováno v:
Molecular Therapy. 10:741-748
Bone marrow stromal cells (MSCs) can be exploited therapeutically in transgenic cell therapy approaches. Our aim was to determine if gene-modified MSCs sequestered within a clinically approved, bovine type I collagen-based viscous bulking material co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dd850372bdd1d64aa3b1a8e3e3cdd8
https://doi.org/10.1016/j.ymthe.2004.07.004
https://doi.org/10.1016/j.ymthe.2004.07.004
Autor:
Abdulaziz Al-Khaldi, Kevin Lachapelle, Jacques Galipeau, Daniel Martineau, Laurence Lejeune, Nicoletta Eliopoulos
Publikováno v:
Gene Therapy. 10:621-629
Bone marrow stromal cells (MSCs) are pluripotent cells capable of differentiation into several tissue types. This present study was performed to determine their functional neoangiogenic potential in vivo. Whole bone marrow was harvested from C57Bl/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a865d4c5cf6a50dfb4ea80ad4c72e12f
https://doi.org/10.1038/sj.gt.3301934
https://doi.org/10.1038/sj.gt.3301934
Autor:
José L. Cohen, Olivier Boyer, Paul J. Martin, David Klatzmann, Laurence Lejeune, Frédéric Charlotte, Sébastien Lacroix-Desmazes
Publikováno v:
Human Gene Therapy. 10:2701-2707
Donor T cells are beneficial for engraftment, immune reconstitution, and antileukemic effects after allogeneic marrow transplantation, but they also cause graft-versus-host disease. Treatment with ganciclovir can control graft-versus-host disease if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f31d95cfeefc4f165a3cede32080552
https://doi.org/10.1089/10430349950016744
https://doi.org/10.1089/10430349950016744
Autor:
Danièle Depétris, Frédéric Charlotte, David Klatzmann, Olivier Boyer, Sylvie Bruel, Laurence Lejeune, Benoit Salamon, R. Onclercq, Marie-Geneviève Mattei, Vanessa Dubus-Bonnet, José L. Cohen
Publikováno v:
Transgenic Research. 7:321-330
Dividing cells expressing the Herpes simplex type 1 thymidine kinase (TK) can be killed upon ganciclovir treatment. Likewise, conditional cell knock-out can be obtained in transgenic mice expressing a TK gene placed under the control of tissue-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c754296bfa6c0fc2e2ad5d3f821caf0
https://doi.org/10.1023/a:1008893206208
https://doi.org/10.1023/a:1008893206208
Publikováno v:
Virology Journal
Virology Journal, Vol 3, Iss 1, p 97 (2006)
Virology Journal, Vol 3, Iss 1, p 97 (2006)
BackgroundT-cell activation leads to signaling pathways that ultimately result in induction of gene transcription from the interleukin-2 (IL-2) promoter. We hypothesized that the IL-2 promoter or its synthetic derivatives can lead to T-cell specific,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041dc7d62bff54c6ff8c357a753a934f
https://doi.org/10.1186/1743-422x-3-97
https://doi.org/10.1186/1743-422x-3-97