Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Laurence Labat"'
Autor:
Jérôme Jeanblanc, Pierre Sauton, Charles Houdant, Sandra Fernandez Rodriguez, Sofia Vilelas de Sousa, Virginie Jeanblanc, Sandra Bodeau, Laurence Labat, Marion Soichot, Florence Vorspan, Mickael Naassila
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Clinical studies on the effectiveness of Baclofen in alcohol use disorder (AUD) yielded mixed results possibly because of differential effects of the enantiomers and sex-related differences. Here we examined the effect of the different
Externí odkaz:
https://doaj.org/article/1ee480dfcf4e42909cb61bc7b687cc6c
Autor:
Philippe Nguyen, Lucie Chevillard, Ahmed S. Gouda, Hervé Gourlain, Laurence Labat, Isabelle Malissin, Nicolas Deye, Sebastian Voicu, Bruno Mégarbane
Publikováno v:
Annals of Intensive Care, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Valproic acid (VPA) poisoning is responsible for life-threatening neurological and metabolic impairments. Despite only low-level evidence of effectiveness, L-carnitine has been used for years to prevent or reverse VPA-related toxi
Externí odkaz:
https://doaj.org/article/7ad3a4dc710e4a938b223316e88989d8
Autor:
Pascal Houzé, Ilona Borowski, Eugénie Bito, Romain Magny, Athina Morcos, Sebastian Voicu, Bruno Mégarbane, Laurence Labat
Publikováno v:
Molecules, Vol 28, Iss 8, p 3466 (2023)
In toxicology, screenings are routinely performed using chromatographic methods coupled to detection systems such as high-resolution mass spectrometry (HR/MS). The increase in specificity and sensitivity of HRMS is responsible for the development of
Externí odkaz:
https://doaj.org/article/cfc72a9dd3004f07892b0b0e19e5ae1d
Autor:
Léa Darnaud, Clément Delage, Youssef Daali, Anne-Priscille Trouvin, Serge Perrot, Nihel Khoudour, Nadia Merise, Laurence Labat, Bruno Etain, Frank Bellivier, Célia Lloret-Linares, Vanessa Bloch, Emmanuel Curis, Xavier Declèves
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 979 (2023)
Drug-metabolizing enzymes and drug transporters are key determinants of drug pharmacokinetics and response. The cocktail-based cytochrome P450 (CYP) and drug transporter phenotyping approach consists in the administration of multiple CYP or transport
Externí odkaz:
https://doaj.org/article/bf3c6f60559b4662a7d219545910343c
Autor:
Romain Magny, Bruno Mégarbane, Pauline Guillaud, Lucie Chevillard, Nicolas Auzeil, Pauline Thiebot, Sebastian Voicu, Isabelle Malissin, Nicolas Deye, Laurence Labat, Pascal Houzé
Publikováno v:
Metabolites, Vol 13, Iss 3, p 353 (2023)
Metabolomics in clinical toxicology aim at reliably identifying and semi-quantifying a broad array of endogenous and exogenous metabolites using dedicated analytical methods. Here, we developed a three-step-based workflow to investigate the metabolic
Externí odkaz:
https://doaj.org/article/8eb6e2080a8d4de5adbc54079846c30d
Autor:
Romain Magny, Nicolas Auzeil, Bertrand Lefrère, Bruno Mégarbane, Pascal Houzé, Laurence Labat
Publikováno v:
Metabolites, Vol 12, Iss 7, p 665 (2022)
Identification of xenobiotics and their phase I/II metabolites in poisoned patients remains challenging. Systematic approaches using bioinformatic tools are needed to detect all compounds as exhaustively as possible. Here, we aimed to assess an analy
Externí odkaz:
https://doaj.org/article/b9901e9278f54ec4a81c1c4ed6844e28
Autor:
Pierre-François Rogliano, Sebastian Voicu, Laurence Labat, Nicolas Deye, Isabelle Malissin, Jean-Louis Laplanche, Dominique Vodovar, Bruno Mégarbane
Publikováno v:
Toxics, Vol 8, Iss 4, p 79 (2020)
Acute kidney injury (AKI) is the major complication of rhabdomyolysis. We aimed to identify the predictive factors for AKI and renal replacement therapy (RRT) requirement in poisoning-associated rhabdomyolysis. We conducted a cohort study including 2
Externí odkaz:
https://doaj.org/article/cf37186aa51b46c1a6521dc38ca26e37
Autor:
Nouzha, Djebrani-Oussedik, Louise, Gütter, Claudia, Soares Barbosa, Héloïse, Foucambert-Millerioux, Laurence, Labat, Joël, Poupon, Virginie, Rigourd
Publikováno v:
In Journal of Trace Elements in Medicine and Biology December 2023 80
Autor:
Pauline Thiebot, Romain Magny, Laetitia Bertolo, Jérôme Langrand, Maurice Mimoun, Pascal Houzé, Laurence Labat
Publikováno v:
Toxicologie Analytique et Clinique. 35:85-92
Publikováno v:
Toxicologie Analytique et Clinique. 34:277-282