Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Laurence K. Jennings"'
Autor:
Sam Afoullouss, Ryan M. Young, Laurence K. Jennings, Jason Doyle, Karen Croke, Debora Livorsi, John H. Adams, Mark P. Johnson, Olivier P. Thomas, A. Louise Allcock
Publikováno v:
ACS Omega, Vol 9, Iss 40, Pp 41914-41922 (2024)
Externí odkaz:
https://doaj.org/article/e98a6bc1eccd4b76aa6927d83e7d51e0
Autor:
Sam Afoullouss, Anthony R. Sanchez, Laurence K. Jennings, Younghoon Kee, A. Louise Allcock, Olivier P. Thomas
Publikováno v:
Marine Drugs, Vol 20, Iss 1, p 52 (2022)
Sponges are at the forefront of marine natural product research. In the deep sea, extreme conditions have driven secondary metabolite pathway evolution such that we might expect deep-sea sponges to yield a broad range of unique natural products. Here
Externí odkaz:
https://doaj.org/article/86f8f5d28621468dbd784ad2281e8af4
Autor:
Laurence K. Jennings, Neyaz M. D. Khan, Navdeep Kaur, Daniel Rodrigues, Christine Morrow, Aoife Boyd, Olivier P. Thomas
Publikováno v:
Molecules, Vol 24, Iss 21, p 3890 (2019)
As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge Spongosorites calcicola for chemical study, as fractions of this species displayed interesting cytotoxic bioactivities a
Externí odkaz:
https://doaj.org/article/41b248087882405cb0219ffedefbab5b
Autor:
Eduardo L. Almeida, Navdeep Kaur, Laurence K. Jennings, Andrés Felipe Carrillo Rincón, Stephen A. Jackson, Olivier P. Thomas, Alan D.W. Dobson
Publikováno v:
Microorganisms, Vol 7, Iss 10, p 394 (2019)
Much recent interest has arisen in investigating Streptomyces isolates derived from the marine environment in the search for new bioactive compounds, particularly those found in association with marine invertebrates, such as sponges. Among these new
Externí odkaz:
https://doaj.org/article/4c96319b460c470ab5841d1212837ad2
Autor:
Maria Miguel-Gordo, Sandra Gegunde, Kevin Calabro, Laurence K. Jennings, Amparo Alfonso, Grégory Genta-Jouve, Jean Vacelet, Luis M. Botana, Olivier P. Thomas
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 319 (2019)
So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical diversity. As part of the Tara Pacific expedition, the first chemical investigation of the sp
Externí odkaz:
https://doaj.org/article/ae3c647e02e9401c8e38a9faf40258b1
Autor:
Dale W. Prebble, Darren C. Holland, Joshua B. Hayton, Francesca Ferretti, Laurence K. Jennings, Jack Everson, Mingming Xu, Milton J. Kiefel, George D. Mellick, Anthony R. Carroll
Publikováno v:
Journal of Natural Products. 86:533-540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63413f741f8e61bdcc1db026e26c23aa
https://doi.org/10.1021/acs.jnatprod.2c01140
https://doi.org/10.1021/acs.jnatprod.2c01140
Anti-prion and α-Synuclein Aggregation Inhibitory Sterols from the Sponge Lamellodysidea cf. chlorea
Autor:
Dale W Prebble, Mingming Xu, Merrick Ekins, Alan L. Munn, Anthony R. Carroll, George D. Mellick, Laurence K. Jennings
Publikováno v:
Journal of Natural Products. 83:3751-3757
In a study aimed at identifying new anti-prion compounds we screened a library of 500 Australian marine invertebrate derived extracts using a yeast-based anti-prion assay. This resulted in an extract from the subtropical sponge Lamellodysidea cf. chl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65b91129de881a39008c9daccd72b01d
https://doi.org/10.1021/acs.jnatprod.0c01168
https://doi.org/10.1021/acs.jnatprod.0c01168
Autor:
Olivier P. Thomas, Daniel Rodrigues, Kevin Calabro, Perrine Lasserre, Laurence K. Jennings, Carmen Ramos, Roisin A. Doohan, Fernando Reyes
Publikováno v:
The Journal of Organic Chemistry. 85:14026-14041
Using both multi-informative molecular network and score-based approaches as prioritization strategies, the Northeastern Atlantic marine terebellid Eupolymnia nebulosa was selected for in-depth chemical investigation. A family of 16 new metabolites n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeb585826b2e6c841358ab8d859e07c4
https://doi.org/10.1021/acs.joc.0c02060
https://doi.org/10.1021/acs.joc.0c02060
Autor:
Olivier P. Thomas, Laurence K. Jennings, Amparo Alfonso, Luis M. Botana, Grégory Genta-Jouve, Kevin Calabro, Maria Miguel-Gordo, Sandra Gegunde
Publikováno v:
Journal Of Natural Products (0163-3864) (Amer Chemical Soc), 2020-07, Vol. 83, N. 7, P. 2299-2304
The chemical investigation of the sponge Stylissa aff. carteri collected around Futuna Islands in the Pacific Ocean led to the isolation of three new dimeric pyrrole 2-aminoimidazole alkaloids (PIAs). Futunamine (1) features an unprecedented pyrrolo[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43d737c57060088229125659a91ac96
https://doi.org/10.1021/acs.jnatprod.0c00223
https://doi.org/10.1021/acs.jnatprod.0c00223
Autor:
Maria Miguel-Gordo, Maggie M. Reddy, Pilar Sánchez, Jordan J. Buckley, Thomas A. Mackenzie, Laurence K. Jennings, Fernando Reyes, Kevin Calabro, Olivier P. Thomas
Publikováno v:
Organicbiomolecular chemistry. 20(5)
An abundant sponge of the order Bubarida was selected for further chemical investigation following biological and chemical screening of sponges collected from Futuna Islands in the Indo-Pacific. Ten new nitrogenous bisabolene derivatives were isolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8d36b01aa3a95839992acaecdeb59d
https://pubmed.ncbi.nlm.nih.gov/35018938
https://pubmed.ncbi.nlm.nih.gov/35018938