Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Laurence Jay Korn"'
Publikováno v:
Nucleic Acids Research. 7:947-958
We have studied initiation of transcription of 5S RNA genes in extracts of Xenopus laevis oocyte nuclei. To aid in this study we developed a general assay for specificity of transcription initiation that does not require accurate termination of trans
Publikováno v:
Journal of Molecular Biology. 117:227-247
The attenuator of the tryptophan (trp) operon of Escherichia coli, located between the promoter and the first major structural gene of the operon, functions as a site of regulated transcription termination (Bertrand et al., 1975). Discrete in vivo RN
Publikováno v:
Nucleic Acids Research. 14:2187-2200
The eucaryotic transcription factor TFIIIA is required for 5S RNA transcription in Xenopus, and changes in the level of TFIIIA have been implicated in the differential expression of 5S RNA genes. In this paper, we report the isolation and sequencing
Publikováno v:
Science. 239:494-497
Regulation of the synthesis of membrane-bound and secreted immunoglobulin mu heavy chains at the level of RNA processing is an important element for B cell development. The precursor mu RNA is either polyadenylated at the upstream poly(A) site (for t
Autor:
Laurence Jay Korn, Charles Yanofsky
Publikováno v:
Journal of Molecular Biology. 103:395-409
Three new polarity suppressors, selected to relieve the polar effect of nonsense mutations in the tryptophan (trp) and lactose (lac) operons of Escherichia coli, increase expression distal to nonsense mutations in both operons to a greater extent tha
Autor:
Laurence Jay Korn, Catherine L. Squires, Terry Platt, Kevin Bertrand, Frank Lee, Craig Squires, Charles Yanofsky
Publikováno v:
Science. 189:22-26
Publikováno v:
Developmental Biology. 36:1-7
β-1,3-Glucanase activity in sand dollar larvae appears at 22 hr of development. The presence of glucose, the major product of this enzyme, in the ambient seawater depresses β-glucanase activity 3-fold. This glucose depression occurs only if glucose
Autor:
Laurence Jay Korn, Yoshihiro Matsumoto
Publikováno v:
Nucleic Acids Research. 16:3801-3814
The DNA sequences required for efficient initiation of transcription of the Xenopus transcription factor IIIA (TFIIIA) gene were determined by microinjecting a series of deletion and linker substitution mutants into Xenopus oocyte nuclei. An upstream
Autor:
Donald D. Brown, Laurence Jay Korn
Publikováno v:
Cell. 15:1145-1156
Genomic Xenopus borealis oocyte-specific 5S DNA (Xbo) contains clusters of 5S rRNA genes. The number of genes varies among clusters, and the distance between genes within a cluster is about 80 nucleotides. The spacer DNA between gene clusters is AT-r
Autor:
Cary Queen, Laurence Jay Korn
Publikováno v:
DNA. 3:421-436
We review a wide range of programs for micro- and minicomputers that facilitate the collection and analysis of DNA, RNA, or protein sequences. Special-purpose programs that perform a single function and general-purpose programs that perform a set of