Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laurence J. Altobell"'
Publikováno v:
Molecular Immunology. 44:2749-2755
The protective antigen (PA 83 ) of Bacillus anthracis is the dominant antigen in natural and vaccine-induced immunity to anthrax infection. Three human single-chain variable fragments (scFvs) against cell bound PA were isolated from an antibody phage
Autor:
Laurence J. Altobell, Mary T. MacDonald, Kim D. Janda, Richard A. Lerner, Lyn H. Jones, Paul Wentworth, Nicholas A. Boyle
Publikováno v:
Angewandte Chemie International Edition. 41:4241-4244
Autor:
Paul Wentworth, Anita D. Wentworth, Laurence J. Altobell, Joseph K. Rogel, Richard A. Lerner, Jorge Nieva, Sangeetha Tripuraneni, Asher Shafton
Publikováno v:
Biochemistry. 47(29)
Antibody light chain (LC) aggregation in vivo leads to the systemic deposition of Ig light chain domains in the form of either amyloid fibrils (AL-amyloidosis) or amorphous deposits, light-chain deposition disease (LCDD), in mainly cardiac or renal t
Autor:
Kim D. Janda, George F. Koob, Peter Wirsching, Longwu Qi, Michael M. Meijler, Laurence J. Altobell, Noboru Yamamoto
Publikováno v:
Journal of medicinal chemistry. 48(23)
Immunopharmacotherapy as an approach to combat drugs of abuse has become an active area of investigation. Marijuana is the most commonly used illicit drug in the U.S. The main active chemical in marijuana is delta9-tetrahydrocannabinol (delta9-THC);
Publikováno v:
Journal of the American Chemical Society. 125(24)
Constrained nicotine analogues were synthesized and coupled to the carrier protein KLH. The immunogenic effects were compared to those using our previously designed flexible nicotine hapten. Immunization of mice with the constrained hapten conjugates
Autor:
Lyn H, Jones, Laurence J, Altobell, Mary T, MacDonald, Nicholas A, Boyle, Paul, Wentworth, Richard A, Lerner, Kim D, Janda
Publikováno v:
Angewandte Chemie (International ed. in English). 41(22)
Autor:
Laurence J. Altobell, Rafaella Sartorio, Emily Jeffries, Kim D. Janda, Bruce Clapham, Jenny M. Mee, Sang-Hyeup Lee, David P. Kujawa, Michael M. Meijler, Gunnar F. Kaufmann
Publikováno v:
Journal of the American Chemical Society. 128:2802-2803
Many bacterial pathogens coordinate their virulence factor expression in a cell density-dependent manner. This population-dependent coordination of gene expression in bacteria has been termed "quorum sensing" (QS). N-Acyl homoserine lactones (AHLs) a
Autor:
Jones, Lyn H., III, Laurence J. Altobell, MacDonald, Mary T., Boyle, Nicholas A., Wentworth, Paul, Jr., Lerner, Richard A., Janda, Kim D.
Publikováno v:
Angewandte Chemie. International Edition; November 15, 2002, Vol. 41 Issue: 22 p4241-4244, 4p