Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Laurence Harewood"'
Autor:
Gail P. Risbridger, Ashlee K. Clark, Laura H. Porter, Roxanne Toivanen, Andrew Bakshi, Natalie L. Lister, David Pook, Carmel J. Pezaro, Shahneen Sandhu, Shivakumar Keerthikumar, Rosalia Quezada Urban, Melissa Papargiris, Jenna Kraska, Heather B. Madsen, Hong Wang, Michelle G. Richards, Birunthi Niranjan, Samantha O’Dea, Linda Teng, William Wheelahan, Zhuoer Li, Nicholas Choo, John F. Ouyang, Heather Thorne, Lisa Devereux, Rodney J. Hicks, Shomik Sengupta, Laurence Harewood, Mahesh Iddawala, Arun A. Azad, Jeremy Goad, Jeremy Grummet, John Kourambas, Edmond M. Kwan, Daniel Moon, Declan G. Murphy, John Pedersen, David Clouston, Sam Norden, Andrew Ryan, Luc Furic, David L. Goode, Mark Frydenberg, Mitchell G. Lawrence, Renea A. Taylor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The prognosis of castration-resistant prostate cancers remains dismal, but accurate preclinical models can lead to effective therapies. Here the Melbourne Urological Research Alliance establish prostate cancer patient-derived xenografts, use the tumo
Externí odkaz:
https://doaj.org/article/72ce33db9321419ba5cb98782c40a1e1
Autor:
Melissa Papargiris, Natalie Lister, Hong Wang, Renea A. Taylor, Sam Norden, Shivakumar Keerthikumar, Andrew Ryan, Mahesh Iddawala, Michelle Richards, David L Goode, Mitchell G. Lawrence, Shomik Sengupta, Andrew Bakshi, Shahneen Sandhu, Jeremy Grummet, Laurence Harewood, John F. Ouyang, David Clouston, Heather Thorne, Luc Furic, Jeremy Goad, Rosalia Quezada Urban, Birunthi Niranjan, Nicholas Choo, Ashlee K. Clark, Carmel Pezaro, Samantha O'Dea, Daniel Moon, Declan G. Murphy, Lisa Devereux, Gail P. Risbridger, Jenna Kraska, Laura H Porter, Mark Frydenberg, Linda Teng, Rodney J. Hicks, Zhuoer Li, Heather B Madsen, David Pook, William Wheelahan, Arun Azad, John Pedersen, Roxanne Toivanen, John Kourambas, Edmond M. Kwan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Preclinical testing is a crucial step in evaluating cancer therapeutics. We aimed to establish a significant resource of patient-derived xenografts (PDXs) of prostate cancer for rapid and systematic evaluation of candidate therapies. The PDX collecti
Autor:
Daniel Moon, Damien M Bolton, Declan G. Murphy, Laurence Harewood, Homayoun Zargar, Justin S. Peters, Uri Hanegbi, Alastair D. Lamb, Dennis King, Paul Ruljancich, Niall M. Corcoran, Dennis Gyomber, Philip Dundee, Mark Frydenberg, Ken Chow, Yee Chan, Anthony J. Costello, David R Webb, Clare Verrill, Lih-Ming Wong, Jeremy Goad, Anthony T. Papenfuss, Andrew Ryan, Marc A. Furrer, Peter Liodakis, Dinesh Agarwal, Nathan Lawrentschuk, Christopher M. Hovens, Justin Bedő
Publikováno v:
European Journal of Cancer. 148:440-450
Background Ductal adenocarcinoma is an uncommon prostate cancer variant. Previous studies suggest that ductal variant histology may be associated with worse clinical outcomes, but these are difficult to interpret. To address this, we performed an int
Autor:
Adrienne R. Hanson, Renea A. Taylor, Andrew Ryan, Mark Frydenberg, Richard J. Rebello, Elena Castro, Christine Henzler, Ross D. Hannan, Shivakumar Keerthikumar, Shelley Lee Hedwards, John Pedersen, David L Goode, Damien M Bolton, Stephen Q. Wong, Rendong Yang, Jeremy Grummet, Sam Norden, Shomik Sengupta, Richard B. Pearson, John Kourambas, Nathan Lawrentschuk, Alisée V. Huglo, Declan G. Murphy, Roxanne Toivanen, Laura H Porter, Daisuke Obinata, Jeremy Goad, Gail P. Risbridger, Mitchell G. Lawrence, Luke A. Selth, Yingming Li, Fernando López-Campos, David Clouston, Jenna Van Gramberg, Shahneen Sandhu, Arun Azad, Ashlee K. Clark, Laurence Harewood, Daniel Moon, Patricia Banks, Luc Furic, Birunthi Niranjan, Hong Wang, Natalie Lister, David Pook, Ross Snow, Scott M. Dehm, Wayne D. Tilley, Heather Thorne, Melissa Papargiris, Carmel Pezaro, Catherine Mitchell
Publikováno v:
European Urology. 74:562-572
Background The intractability of castration-resistant prostate cancer (CRPC) is exacerbated by tumour heterogeneity, including diverse alterations to the androgen receptor (AR) axis and AR-independent phenotypes. The availability of additional models
Autor:
David R Webb, Zita Ballok, Ben Tran, Nathan Lawrentschuk, Andrew Troy, Phil Dundee, Michael S Hofman, Justin S. Peters, Shankar Siva, Angelyn Anton, Yee Chan, Patrick Bowden, Niall M. Corcoran, Anthony J. Costello, Declan G. Murphy, Laurence Harewood, Andrew W. See, Olfat Kamel Hasan
Publikováno v:
BJU internationalReferences. 126(4)
Prostate-specific membrane antigen (PSMA) PET/CT imaging is increasingly being utilised in clinical practice, demonstrating greater sensitivity in the detection of metastatic prostate cancer (mPC) compared to conventional imaging [1]. Prior studies h
Autor:
Nathan Lawrentschuk, Mouth Waverley, Yee Chan, Paul Ruljancich, Dennis King, Niall M. Corcoran, Anthony J. Costello, Mark Frydenberg, Declan G. Murphy, Lih-Ming Wong, Justin S. Peters, Homayoun Zargar, Jeremy Goad, Laurence Harewood, Dennis Gyomber, Alastair D. Lamb, Andrew Ryan, Damien M Bolton, Philip Dundee, Peter Liodakis, Dinesh Agarwal, Ken Chow, Clare Verrill, Christopher M. Hovens, Marc A. Furrer, Uri Hanegbi, David R Webb, Daniel Moon
Publikováno v:
Journal of Urology. 203
Autor:
Niall M. Corcoran, Laurence Harewood, Anthony J. Costello, Justin S. Peters, Ryan Stuchbery, Geoff Macintyre, Christopher M. Hovens, Marek Cmero
Publikováno v:
Oncotarget
// Ryan Stuchbery 1, 2, 4 , Geoff Macintyre 3 , Marek Cmero 3 , Laurence M. Harewood 2, 4 , Justin S. Peters 2, 4 , Anthony J. Costello 1, 2, 4 , Christopher M. Hovens 1, 2, 4 , Niall M. Corcoran 1, 2, 4 1 Australian Prostate Cancer Research Centre E
Autor:
Laurence Harewood, David R Webb, Michael S Hofman, Justin S. Peters, A. See, Tony Costello, Andrew Troy, Declan G. Murphy, Y. Chan, Angelyn Anton, Philip Dundee, Nathan Lawrentschuk, Ben Tran, Zita Ballok, Niall M. Corcoran, Shankar Siva, Patrick Bowden
Publikováno v:
Annals of Oncology. 29:ix70-ix71
Autor:
Laurence Harewood, James G. Huang, Niall M. Corcoran, Justin S. Peters, Anthony J. Costello, Matthew K.H. Hong, Christopher M. Hovens, John Pedersen
Publikováno v:
BJU International. 111:921-927
What's known on the subject? and What does the study add? The presence of a positive pathological margin is an independent risk factor for clinically significant disease recurrence only in intermediate-risk disease when the a priori risk of micrometa
Autor:
Justin S. Peters, Niall M. Corcoran, Anthony J. Costello, Laurence Harewood, Nikhil Sapre, John Pedersen, Christopher M. Hovens, Matthew K.H. Hong
Publikováno v:
BJU International. 110:58-63
Objective • To examine the impact of seminal vesicle invasion (SVI) in patients with locally advanced (pT3) prostate cancer on clinical outcome. • To explore the clinical association of SVI with metastatic disease. • To distinguish between the