Rapeseed Lecithin Increases Lymphatic Lipid Output and α-Linolenic Acid Bioavailability in Rats

Autor: Chloé Robert, Charline Buisson, Laurence Fonseca, Elisabeth Errazuriz-Cerda, Carole Vaysse, Emmanuelle Meugnier, Leslie Couëdelo, Emmanuelle Loizon, Marie-Caroline Michalski, Carole Knibbe

Publikováno v: Journal of Nutrition
Journal of Nutrition, American Society for Nutrition, 2020, 150 (11), pp.2900-2911. ⟨10.1093/jn/nxaa244⟩
Journal of Nutrition, 2020, 150 (11), pp.2900-2911. ⟨10.1093/jn/nxaa244⟩

International audience; Background: Soybean lecithin, a plant-based emulsifier widely used in food, is capable of modulating postprandial lipid metabolism. With arising concerns of sustainability, alternative sources of vegetal lecithin are urgently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b690f39655cc4d9010f9c65dd6015a89
https://hal.archives-ouvertes.fr/hal-03149749

A critical assessment of transmethylation procedures for n-3 long-chain polyunsaturated fatty acid quantification of lipid classes

Autor: Laurence Fonseca, Leslie Couëdelo, Anthony Sehl, Carole Vaysse, Maud Cansell

Publikováno v: Food Chemistry
Food Chemistry, Elsevier, In press, 251, pp.1-8. ⟨10.1016/j.foodchem.2018.01.060⟩

Lipid transmethylation methods described in the literature are not always evaluated with care so to insure that the methods are effective, especially on food matrix or biological samples containing polyunsaturated fatty acid (PUFA). The aim of the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04d93d01dc58081508d2d8d735729be
https://pubmed.ncbi.nlm.nih.gov/29426414

Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis

Autor: Frédéric Fotiadu, Vanessa Point, Laurence Fonseca, Carole Vaysse, Julie Zarrillo, Brigitt Raux, Gérard Buono, Julien Leclaire, Romain Magnez, Frédéric Carrière, Anaïs Bénarouche, Leslie Couëdelo, Alexandre Guy, Thierry Durand, Jean-François Cavalier

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2016, 123 (834-848), ⟨10.1016/j.ejmech.2016.08.009⟩
European Journal of Medicinal Chemistry, 2016, 123 (834-848), ⟨10.1016/j.ejmech.2016.08.009⟩

International audience; Based on a previous study and in silico molecular docking experiments, we have designed and synthesized a new series of ten 5-Alkoxy-N-3-(3-PhenoxyPhenyl)-1,3,4-Oxadiazol-2(3H)-one derivatives (RmPPOX). These molecules were fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c222b77a75980ea02e283170afd642b2
https://hal.archives-ouvertes.fr/hal-01466841

Impact of various emulsifiers on ALA bioavailability and chylomicron synthesis through changes in gastrointestinal lipolysis

Autor: Frédéric Carrière, Julien Monteil, Gaëlle Pineau, Laurence Fonseca, Manon Lecomte, Leslie Couëdelo, Sawsan Amara, Maud Cansell, Carole Vaysse, Emmanuelle Meugnier, Marie-Caroline Michalski

Publikováno v: Food and Function
Food and Function, Cambridge : Royal Society of Chemistry, 2015, 6 (5), pp.1726-1735. ⟨10.1039/C5FO00070J⟩
Food and Function, Cambridge : Royal Society of Chemistry, 2015, 6 (5), pp.1726-1735. ⟨10.1039/c5fo00070j⟩
Food and Function, 2015, 6 (5), pp.1726-1735. ⟨10.1039/c5fo00070j⟩

International audience; Formulating healthy food rich in omega 3 fatty acids requires prior knowledge of the parameters influencing their bioavailability and their metabolic fate. In this context, we studied the effects of various emulsifiers widely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab965a69ad6250ec4a4a6da0727c496
https://hal.archives-ouvertes.fr/hal-01981675