Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Laurence Dewachter"'
Autor:
Bruno Garcia, Benoit ter Schiphorst, Karine Santos, Fuhong Su, Laurence Dewachter, Francisco Vasques-Nóvoa, Estela Rocha-Oliveira, Roberto Roncon-Albuquerque, Theo Uba, Oliver Hartmann, Adrien Picod, Feriel Azibani, Jacques Callebert, Serge Goldman, Filippo Annoni, Raphaël Favory, Jean-Louis Vincent, Jacques Creteur, Fabio Silvio Taccone, Alexandre Mebazaa, Antoine Herpain
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Dipeptidyl peptidase 3 (DPP3) is a ubiquitous cytosolic enzyme released into the bloodstream after tissue injury, that can degrade angiotensin II. High concentrations of circulating DPP3 (cDPP3) have been associated with worse out
Externí odkaz:
https://doaj.org/article/26b2ee6ba727427889ab7b469a6a7906
Autor:
Kaoutar Idouz, Asmae Belhaj, Benoit Rondelet, Laurence Dewachter, Bruno Flamion, Nathalie Kirschvink, Sophie Dogné
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Brain death (BD) is a complex medical state that triggers systemic disturbances and a cascade of pathophysiological processes. This condition significantly impairs both kidney function and structural integrity, thereby presenting considerable challen
Externí odkaz:
https://doaj.org/article/1a656c04218341598e07ec2c021233c9
Autor:
Géraldine Hubesch, Céline Dewachter, Laura Chomette, Emeline Hupkens, Pascale Jespers, Grégory Vegh, Mathilde Doppler, Umair Sheikh Mohammad, Anaïs Thiriard, Myriam Remmelink, Jean‐Luc Vachiéry, Kathleen McEntee, Laurence Dewachter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 11 (2024)
Background Pulmonary hypertension and right ventricular (RV) dysfunction are major prognostic determinants in patients with heart failure with preserved ejection fraction (HFpEF). The underlying pathomechanisms remain unknown. In this context, we sou
Externí odkaz:
https://doaj.org/article/2cc8160322f04c6a8135d3c82c38a4cf
Autor:
Bruno Garcia, Fuhong Su, Francesca Manicone, Laurence Dewachter, Raphaël Favory, Amina Khaldi, Alexander Moiroux-Sahroui, Anthony Moreau, Antoine Herpain, Jean-Louis Vincent, Jacques Creteur, Fabio Silvio Taccone, Filippo Annoni
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-10 (2023)
Abstract Background Alterations in the renin–angiotensin system have been implicated in the pathophysiology of septic shock. In particular, angiotensin 1–7 (Ang-(1–7)), an anti-inflammatory heptapeptide, has been hypothesized to have beneficial
Externí odkaz:
https://doaj.org/article/f9688f116df3480ba774629751bd5c2a
Autor:
Bruno Garcia, Fuhong Su, Laurence Dewachter, Raphaël Favory, Amina Khaldi, Alexander Moiroux-Sahraoui, Filippo Annoni, Francisco Vasques-Nóvoa, Estela Rocha-Oliveira, Roberto Roncon-Albuquerque, Geraldine Hubesch, Hassane Njimi, Jean-Louis Vincent, Fabio S. Taccone, Jacques Creteur, Antoine Herpain
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-13 (2022)
Abstract Background Angiotensin II is one of the vasopressors available for use in septic shock. However, its effects on the septic myocardium remain unclear. The aim of the study was to compare the effects of angiotensin II and norepinephrine on car
Externí odkaz:
https://doaj.org/article/39891891ee944cc9803ba90e223d342e
Autor:
Asmae Belhaj, Laurence Dewachter, Astrid Monier, Gregory Vegh, Sandrine Rorive, Myriam Remmelink, Mélanie Closset, Christian Melot, Jacques Creteur, Isabelle Salmon, Benoît Rondelet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10439 (2023)
Background: Right ventricular (RV) dysfunction remains a major problem after heart transplantation and may be associated with brain death (BD) in a donor. A calcineurin inhibitor tacrolimus was recently found to have beneficial effects on heart funct
Externí odkaz:
https://doaj.org/article/e4e0352a36c74e2c8223925e23edebe1
Autor:
Abdelhamid Sahraoui, Céline Dewachter, Grégory Vegh, Kathleen Mc Entee, Robert Naeije, Souhila Aouichat Bouguerra, Laurence Dewachter
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background In metabolic disorders, myocardial fatty infiltration is critically associated with lipotoxic cardiomyopathy. Methods Twenty Psammomys obesus gerbils were randomly assigned to normal plant or high fat diet. Sixteen weeks later, my
Externí odkaz:
https://doaj.org/article/990a7a2830d64e72b6616d7a02e16a99
Autor:
Géraldine Hubesch, Aliénor Hanthazi, Angela Acheampong, Laura Chomette, Hélène Lasolle, Emeline Hupkens, Pascale Jespers, Grégory Vegh, Cécile Watu Malu Wembonyama, Caroline Verhoeven, Céline Dewachter, Jean-Luc Vachiery, Kathleen Mc Entee, Laurence Dewachter
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Heart failure with preserved ejection fraction (HFpEF) is a common complex clinical syndrome for which there are currently few evidence-based therapies. As patients with HFpEF very often present with comorbidities comprising the metabolic syndrome, w
Externí odkaz:
https://doaj.org/article/72de21e6cc9e4ec3b6d34eeb880b5479
Autor:
Bachar El Oumeiri, Laurence Dewachter, Philippe Van de Borne, Géraldine Hubesch, Christian Melot, Pascale Jespers, Constantin Stefanidis, Kathleen Mc Entee, Frédéric Vanden Eynden
Publikováno v:
Genes, Vol 14, Iss 1, p 122 (2023)
To explore the impact of omecamtiv mecarbil (OM) on the gene expression profile in adult male rats. Fourteen male Wistar rats were randomly assigned to a single OM (1.2 mg/kg/h; n = 6) or placebo (n = 8) 30-min infusion. Echocardiography was performe
Externí odkaz:
https://doaj.org/article/e444de2f82fd49dca2adf0717f506cd3
Autor:
Céline Boudart, Fuhong Su, Lorenzo Pitisci, Arnaud Dhoine, Olivier Duranteau, Pascale Jespers, Antoine Herpain, Rebecca Vanderpool, Serge Brimioulle, Jacques Creteur, Robert Naeije, Luc Van Obbergh, Laurence Dewachter
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Sepsis is a common condition known to impair blood flow regulation and microcirculation, which can ultimately lead to organ dysfunction but such contribution of the coronary circulation remains to be clarified. We investigated coronary bl
Externí odkaz:
https://doaj.org/article/73a1ba16fb83406b885c71c9121e144f