Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laurence Denat"'
Autor:
Philippe Perez, Laurence Denat, Dominique Erdmann, Jean-Philippe Belaïdi, Laurent Marrot, Ariane Dimitrov, Christophe Jones, Guillaume Lereaux, Martine Zanini, Joan Eilstein, Jeremie Soeur, Olivia Zobiri, Christel Chollet, Sakina Mezzache
Publikováno v:
Journal of Dermatological Science. 86:162-169
Background It is likely that skin is exposed to low concentrations of pollutants such as Polycyclic Aromatic Hydrocarbons (PAH) either through topical penetration by ultrafine particles or by systemic distribution. No precise estimation of pollutants
Autor:
Manuelle Ducoux-Petit, Catherine Muller, Lionel Larue, Odile Burlet-Schiltz, Emily Clement, Stéphanie Balor, Stéphanie Dauvillier, Laurence Denat, Laurence Nieto, Vanessa Soldan, Ikrame Lazar
Publikováno v:
Pigment Cell & Melanoma Research. 28:464-475
Summary Exosomes are important mediators in cell-to-cell communication and, recently, their role in melanoma progression has been brought to light. Here, we characterized exosomes secreted by seven melanoma cell lines with varying degrees of aggressi
Publikováno v:
The Journal of investigative dermatology
Epidermal melanocytes are particularly vulnerable to oxidative stress owing to the pro-oxidant state generated during melanin synthesis, and to the intrinsic antioxidant defenses that are compromised in pathologic conditions. Melanoma is thought to b
Autor:
Alessandro Testori, Mercedes Rodríguez, Jane C. Goodall, Paolo Nuciforo, Laurence Denat, Colin R. Goding, Lionel Larue, Suzanne Carreira, Keith S. Hoek
The ability of cancer cells to acquire properties of invasiveness and the potential to metastasize is not entirely understood. In the traditional model, genetic instability within a tumor would lead within some cells to the accumulation of genetic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bf5b2780166638ac1ab191627c160f
https://ora.ox.ac.uk/objects/uuid:9c9ca119-5b92-42fe-87a0-5babeedd574e
https://ora.ox.ac.uk/objects/uuid:9c9ca119-5b92-42fe-87a0-5babeedd574e
Autor:
Ossia M. Eichhoff, Keith S. Hoek, Mai Xu, Marie C. Zipser, Lydia Kriegl, Lionel Larue, Thomas Kirchner, Ashani T. Weeraratna, Laurence Denat, Daniel S. Widmer, Reinhard Dummer
Publikováno v:
Pigment Cell & Melanoma Research. 24:631-642
Recent observations suggest that melanoma cells drive disease progression by switching back and forth between phenotypic states of proliferation and invasion. Phenotype switching has been linked to changes in Wnt signalling, and we therefore looked f
Autor:
Laurence Denat, Colin R. Goding, Irwin Davidson, Delphine Champeval, Anne-Lise Steunou, Véronique Delmas, Laurence Nieto, Irina Berlin, Isabel Puig, Yveline Bourgeois, Elise Bonvin, Karen Roberts, Lionel Larue, Sophie Colombo
Publikováno v:
Molecular and cellular biology. 32(7)
MITF-M and PAX3 are proteins central to the establishment and transformation of the melanocyte lineage. They control various cellular mechanisms, including migration and proliferation. BRN2 is a POU domain transcription factor expressed in melanoma c
Autor:
Aurélie Herbette, Silvia Martinozzi, Colin R. Goding, Véronique Delmas, Flavie Luciani, Florian De Vuyst, Laurence Denat, Robert Ballotti, Bouchra Aylaj, Lionel Larue, Rolf Kemler, Delphine Champeval
Publikováno v:
Development (Cambridge, England). 138(18)
We aim to evaluate environmental and genetic effects on the expansion/proliferation of committed single cells during embryonic development, using melanoblasts as a paradigm to model this phenomenon. Melanoblasts are a specific type of cell that displ
Autor:
Ossia M, Eichhoff, Ashani, Weeraratna, Marie C, Zipser, Laurence, Denat, Daniel S, Widmer, Mai, Xu, Lydia, Kriegl, Thomas, Kirchner, Lionel, Larue, Reinhard, Dummer, Keith S, Hoek
Publikováno v:
Pigment cell & melanoma research
Recent observations suggest that melanoma cells drive disease progression by switching back and forth between phenotypic states of proliferation and invasion. Phenotype switching has been linked to changes in Wnt signalling, and we therefore looked f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40364728c7e9dc85d162cdf28ef4174c
Autor:
Lionel Larue, Richard A. Sturm, Jane C. Goodall, Colin R. Goding, Laurence Denat, Dominique Kobi, Paolo Nuciforo, Irwin Davidson, Suzanne Carreira
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7788-94. ⟨10.1158/0008-5472.CAN-08-1053⟩
Cancer Research, 2008, 68 (19), pp.7788-94. ⟨10.1158/0008-5472.CAN-08-1053⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7788-94. ⟨10.1158/0008-5472.CAN-08-1053⟩
Cancer Research, 2008, 68 (19), pp.7788-94. ⟨10.1158/0008-5472.CAN-08-1053⟩
The origin of tumor heterogeneity is poorly understood, yet it represents a major barrier to effective therapy. In melanoma and in melanocyte development, the microphthalmia-associated transcription factor (Mitf) controls survival, differentiation, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231ce2736e01ef82344955e94a03d765
https://www.hal.inserm.fr/inserm-00350760
https://www.hal.inserm.fr/inserm-00350760
Autor:
Robert Moore, Sylvia Julien-Grille, Alfonso Bellacosa, Laurence Denat, Véronique Delmas, Lionel Larue, Olivier G. Morali
Publikováno v:
Rise and Fall of Epithelial Phenotype ISBN: 9780306482397
IGFs (insulin-like growth factors) are peptides known to stimulate a wide range of actions on different tissues. Indeed, IGFs can stimulate anabolism, acute metabolic effects as well as enhancing more chronic effects such as cell proliferation and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::827382c6687aced72dc1dc406fefb89d
https://doi.org/10.1007/0-387-28671-3_14
https://doi.org/10.1007/0-387-28671-3_14