Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laurence Del Frari"'
Autor:
Micaela B. Reddy, Michael B. Bolger, Grace Fraczkiewicz, Laurence Del Frari, Laibin Luo, Viera Lukacova, Amitava Mitra, Joyce S. Macwan, Jim M. Mullin, Neil Parrott, Aki T. Heikkinen
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1325 (2021)
Uridine 5′-diphospho-glucuronosyltransferases (UGTs) are expressed in the small intestines, but prediction of first-pass extraction from the related metabolism is not well studied. This work assesses physiologically based pharmacokinetic (PBPK) mod
Externí odkaz:
https://doaj.org/article/f5e82495484f416fb736034f0fa4ac9c
Autor:
Laibin Luo, James M. Mullin, Viera Lukacova, Michael B. Bolger, Laurence Del Frari, Grace Fraczkiewicz, Amitava Mitra, Micaela B Reddy, Joyce S. Macwan, Aki T. Heikkinen, Neil Parrott
Publikováno v:
Pharmaceutics, Vol 13, Iss 1325, p 1325 (2021)
Pharmaceutics
Pharmaceutics
Uridine 5′-diphospho-glucuronosyltransferases (UGTs) are expressed in the small intestines, but prediction of first-pass extraction from the related metabolism is not well studied. This work assesses physiologically based pharmacokinetic (PBPK) mod
Autor:
Laurent Guibaud, Laurence Del Frari, Jean-Philippe Lacour, Valérie Brunner, Sébastien Barbarot, Alain Delarue, Jean-Jacques Voisard, Christine Léauté-Labrèze, Christine Chaumont
Publikováno v:
Pharmacology Research & Perspectives
Propranolol has become the first choice therapy for complicated Infantile Hemangiomas (IH). The pharmacokinetics of propranolol were evaluated after repeated oral administration of a new pediatric solution of propranolol at 3 mg kg−1 day−1 given