Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Laurence Catley"'
Autor:
Kenneth C. Anderson, Ruojie Wang, Yu-Tzu Tai, Masood A. Shammas, Laurence Catley, Mark A. Exley, Weihua Song, Steven P. Balk, Hans van Vliet, Klaus Podar, Nikhil C. Munshi, Rao Prabhala
Publikováno v:
Song, W, van der Vliet, J J, Tai, Y T, Prabhala, R, Wang, R, Podar, K, Catley, L, Shammas, M A, Anderson, K C, Balk, S P, Exley, M A & Munshi, N C 2008, ' Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: a strategy for immunotherapy ', Clinical Cancer Research, vol. 14, no. 21, pp. 6955-6962 . https://doi.org/10.1158/1078-0432.CCR-07-5290
Clinical Cancer Research, 14(21), 6955-6962. American Association for Cancer Research Inc.
Clinical Cancer Research, 14(21), 6955-6962. American Association for Cancer Research Inc.
Purpose: CD1d-restricted invariant natural killer T (iNKT) cells are important immunoregulatory cells in antitumor immune responses. However, the quantitative and qualitative defects of iNKT cells in advanced multiple myeloma hamper their antitumor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e841ad049c3f488d514ef7e3eb5c3e
https://doi.org/10.1158/1078-0432.ccr-07-5290
https://doi.org/10.1158/1078-0432.ccr-07-5290
Autor:
Laurence Catley, Samantha Pozzi, Kenji Ishitsuka, Enrique M. Ocio, Hiroshi Yasui, Noopur Raje, Norihiko Shiraishi, Dharminder Chauhan, Hiroshi Ikeda, Tanyel Kiziltepe, Yutaka Okawa, Teru Hideshima, Kenneth C. Anderson, Sonia Vallet
Publikováno v:
Molecular Cancer Therapeutics. 6:1718-1727
In this study, we investigated the cytotoxicity of 5-azacytidine, a DNA methyltransferase inhibitor, against multiple myeloma (MM) cells, and characterized DNA damage–related mechanisms of cell death. 5-Azacytidine showed significant cytotoxicity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680bff769cdfa707b87045086c47d9bf
https://doi.org/10.1158/1535-7163.mct-07-0010
https://doi.org/10.1158/1535-7163.mct-07-0010
Autor:
Paola Neri, Dharminder Chauhan, Iris Breitkreutz, Kenneth C. Anderson, Yu-Tzu Tai, Laurence Catley, Robert L. Schlossman, Xian-Feng Li, Weihua Song, Klaus Podar, Teru Hideshima, Noopur Raje, Nikhil C. Munshi, Paul G. Richardson
Publikováno v:
Cancer Research. 66:6675-6682
Recent studies have underscored the role of B-cell-activating factor (BAFF), a member of the tumor necrosis factor superfamily, in promoting the survival of malignant B cells, including human multiple myeloma. We here characterized the functional sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59aa842192de842215e941de3770a64d
https://doi.org/10.1158/0008-5472.can-06-0190
https://doi.org/10.1158/0008-5472.can-06-0190
Autor:
Laurence Catley, Reshma Shringarpure, Paul J. Galardy, Deepak Bhole, Teru Hideshima, Hidde L. Ploegh, Constantine S. Mitsiades, Nikhil C. Munshi, Klaus Podar, Renate Burger, Kenneth C. Anderson, Pierfrancesco Tassone, Benedikt M. Kessler, Dharminder Chauhan, Yu-Tzu Tai
Publikováno v:
British Journal of Haematology. 134:145-156
The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM). Although bortezomib is known to be a selective proteasome inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ada76627f197e85c45c8134856e91ab
https://doi.org/10.1111/j.1365-2141.2006.06132.x
https://doi.org/10.1111/j.1365-2141.2006.06132.x
Autor:
Laurence Catley, Kenneth Anderson
Publikováno v:
Current Cancer Therapy Reviews. 2:169-183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ecdb3aee5eba1218a6fd106496527f
https://doi.org/10.2174/157339406776872807
https://doi.org/10.2174/157339406776872807
Autor:
Mugdha Velankar, Anthony Letai, Teru Hideshima, N. Mitsiades, Constantine S. Mitsiades, Dharminder Chauhan, Ta-Hsiang Chao, Huib Ovaa, Klaus Podar, Paul G. Richardson, Michael A. Palladino, Saskia T. C. Neuteboom, Kenneth C. Anderson, Benjamin Nicholson, Hiroshi Yasui, Celia R. Berkers, Guilan Li, Laurence Catley
Publikováno v:
Cancer Cell. 8(5):407-419
SummaryBortezomib therapy has proven successful for the treatment of relapsed and/or refractory multiple myeloma (MM); however, prolonged treatment is associated with toxicity and development of drug resistance. Here, we show that the novel proteasom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8876b67ab304765b274623758ae983
Publikováno v:
Drug Resistance Updates. 8:205-218
The introduction of melphalan and prednisone 40 years ago was a significant advance in the treatment of multiple myeloma (MM). In the following decades, significant advances were few, but included landmarks, such as the introduction of VAD and autolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60dabdc7f56f5c4a63b112d1297bade2
https://doi.org/10.1016/j.drup.2005.06.001
https://doi.org/10.1016/j.drup.2005.06.001
Autor:
Klaus Podar, Kenneth C. Anderson, Markus Wartmann, James D. Griffin, Laurence Catley, Boris Lin, Dharminder Chauhan, Richard Leblanc, Constantine S. Mitsiades, Renate Burger, Yu-Tzu Tai
Publikováno v:
Blood. 105:350-357
In this study, we investigated the in vitro and in vivo efficacy of patupilone (epothilone B, EPO906), a novel nontaxane microtubule stabilizing agent, in treatment of multiple myeloma (MM). Patupilone directly inhibited growth and survival of MM cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e7c93ec133e73a49e99bc7e4e2d48d
https://doi.org/10.1182/blood-2004-06-2499
https://doi.org/10.1182/blood-2004-06-2499
Autor:
Toshiaki Hayashi, Yu-Tzu Tai, Reshma Shringarpure, Laurence Catley, Dharminder Chauhan, Teru Hideshima, Paul G. Richardson, Kenneth C. Anderson, Renate Burger, Robert L. Schlossman, Lini Pandite, Klaus Podar, Pedro Carvalho, Rajesh Kumar
Publikováno v:
Blood. 103:3474-3479
Previous studies have shown that the multiple myeloma (MM) cell line and MM patient cells express high-affinity vascular endothelial growth factor (VEGF) receptor-1 or Fms-like tyrosine kinase-1 (Flt-1) but not VEGF receptor-2 or Flk-1/kinase insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6c95f0b0455ddb0344ed752e987245
https://doi.org/10.1182/blood-2003-10-3527
https://doi.org/10.1182/blood-2003-10-3527
Autor:
Michael B. Sporn, Mitsiades Constantine S, Paul G. Richardson, Kenneth C. Anderson, Yu-Tzu Tai, Guilan Li, Klaus Podar, Teru Hideshima, Nanjoo Suh, Nikhil C. Munshi, Gordon W. Gribble, Reshma Shringarpure, Dharminder Chauhan, Laurence Catley, Tadashi Honda, Robert L. Schlossman
Publikováno v:
Blood. 103:3158-3166
The synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO) induces apoptosis in leukemic cells. Here we show that CDDO and its new derivative CDDO-imidazolide (CDDO-Im) trigger apoptosis in multiple myeloma (MM) cells resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df6986a99423bfb01dce02eb9c09666
https://doi.org/10.1182/blood-2003-08-2873
https://doi.org/10.1182/blood-2003-08-2873