Development and Evaluation of a DNA Enzyme Immunoassay Method for env Genotyping of Subtypes A through G of Human Immunodeficiency Virus Type 1 Group M, with Discrimination of the Circulating Recombinant Forms CRF01_AE and CRF02_AG

Autor: Francis Barin, Eitel Mpoudi-Ngole, Eric Delaporte, Isabelle Farfara, Florence Damond, Jean-Christophe Plantier, Françoise Brun-Vézinet, Souleymane Mboup, Denys Brand, Laurence Buzelay, Martine Peeters, Laurence Vergne

Publikováno v: Journal of Clinical Microbiology. 40:1010-1022

The tools currently available for genetic subtyping of human immunodeficiency virus type 1 are laborious or can be used only for the analysis of a limited number of samples and/or subtypes. We developed and evaluated a molecular biology-based method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4ad46e12bfa9a8c56839c0290550546
https://doi.org/10.1128/jcm.40.3.1010-1022.2002

Ultrastructural and physicochemical characterization of the hepatitis C virus recovered from the serum of an agammaglobulinemic patient

Autor: Laurence Buzelay, Alain Goudeau, Philippe Roingeard, Francis Barin, Frédéric Dubois, A. Trestard, Yannick Bacq

Publikováno v: Archives of Virology. 143:2241-2245

Hepatitis C virus (HCV) morphology and physicochemical properties remain unclear because HCV usually circulates in a complexed form in association with immunoglobulins. In the present work, we were interested in the characterization of HCV particles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91b202c7391c692d3a2cd9a240e26be
https://doi.org/10.1007/s007050050455

Diversity of Antibody Binding to V3 Peptides Representing Consensus Sequences of HIV Type 1 Genotypes A to E: An Approach for HIV Type 1 Serological Subtyping

Autor: Bernard Lejeune, Christian Mathiot, Souleymane Mboup, Laurence Buzelay, François Denis, Vicharn Vithayasai, Armelle Baillou-Beaufils, Yousra Lahbabi, Alain Goudeau, Ursula Dietrich, Francis Barin

Publikováno v: AIDS Research and Human Retroviruses. 12:1279-1289

We investigated whether V3-binding assays might be useful to analyze human immunodeficiency virus type 1 (HIV-1) variants in different geographic regions. We showed that strong cross-reactivity between subtype-specific V3 peptides is almost inevitabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a64b537f4502b4bae838d8c998bdcd
https://doi.org/10.1089/aid.1996.12.1279

Immunogenicity of recombinant envelope glycoproteins derived from T-cell line-adapted isolates or primary HIV isolates: a comparative study using multivalent vaccine approaches

Autor: Francis Barin, Laurence Buzelay, Franck Lemiale, Bernard Verrier, Sarah Lebigot, Denys Brand, Sylvie Brunet

Publikováno v: Journal of Acquired Immune Deficiency Syndromes
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2001, 26, pp.413-422

International audience; We investigated immunogenic properties of native envelope glycoproteins derived from HIV-1 (subtype B). Our main objective was to assess whether the design of multivalent vaccines affects generation of neutralizing antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12607bc45f1e8a41b3449052f1f8d14a
https://hal.archives-ouvertes.fr/hal-00315051

Comparative analysis of humoral immune responses to HIV type 1 envelope glycoproteins in mice immunized with a DNA vaccine, recombinant Semliki Forest virus RNA, or recombinant Semliki Forest virus particles

Autor: Sylvie Brunet, Laurence Buzelay, Francis Barin, Franck Lemiale, Denys Brand, Isabelle Turbica

Publikováno v: AIDS research and human retroviruses. 14(15)

The Semliki Forest virus (SFV) system seems to be a useful new approach for generating effective immune responses against HIV-1 in animal models. We evaluated this system by comparing the humoral immune responses raised in mice immunized against the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5789718363decf117e8c5a6743371b7a
https://pubmed.ncbi.nlm.nih.gov/9788678