Synthesis of novel C-nucleoside analogues bearing an anomeric cyano and a 1,2,3-triazole nucleobase as potential antiviral agents

Autor: Pierre Sierocki, Krystal Gaillard, Ruben Arturo Arellano Reyes, Chloé Donnart, Emilie Lambert, Sandrine Grosse, Laurence Arzel, Arnaud Tessier, Jerome Guillemont, Monique Mathé-Allainmat, Jacques Lebreton

Publikováno v: Organic & Biomolecular Chemistry. 20:2715-2728

We report the synthesis of C-nucleosides with a quaternary carbon at the anomeric position tethered to a 4-substituted 1,2,3-triazole ring and a cyano group, which were developed as potential antiviral agents.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5808d33064b0cdee660e899626f0b203
https://doi.org/10.1039/d1ob02451e

Synthesis of novel

Autor: Pierre, Sierocki, Krystal, Gaillard, Ruben Arturo, Arellano Reyes, Chloé, Donnart, Emilie, Lambert, Sandrine, Grosse, Laurence, Arzel, Arnaud, Tessier, Jerome, Guillemont, Monique, Mathé-Allainmat, Jacques, Lebreton

Publikováno v: Organicbiomolecular chemistry. 20(13)

A linear sequence to access a novel series of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12be39c59e11fe3baeb376f579cf95f9
https://pubmed.ncbi.nlm.nih.gov/35293914

Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization

Autor: Yannick Jacques, Monique Mathé-Allainmat, Laurence Arzel, Mike Maillasson, Erwan Mortier, Jacques Lebreton, Romy Vomiandry, Didier Dubreuil, Agnès Quéméner, Benoit Sicard

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (14), pp.6249-6272. ⟨10.1021/acs.jmedchem.7b00485⟩
Journal of Medicinal Chemistry, 2017, 60 (14), pp.6249-6272. ⟨10.1021/acs.jmedchem.7b00485⟩

International audience; Interleukin (IL)-15 is a pleiotropic cytokine, which is structurally close to IL-2 and shares with it the IL-2 β and γ receptor (R) subunits. By promoting the activation and proliferation of NK, NK-T and CD8+ T cells, IL-15

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f18072fe15c29cae48a1aabec52bef
https://doi.org/10.1021/acs.jmedchem.7b00485

Picasso-Picabia : la peinture au défi

Autor: Laurence Arzel Nadal

Publikováno v: Critique d’art.

Publie et realise par Somogy editions d’Art, l’ouvrage Picasso-Picabia : la peinture au defi accompagne avantageusement l’exposition du meme titre presentee au musee Granet d’Aix-en-Provence. Le catalogue, dans sa mise en page originale, a la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77993e7c8fff77d7491ab5891b5178af
https://doi.org/10.4000/critiquedart.36794

François Michaud, Martin Jannink

Autor: Laurence Arzel Nadal

Publikováno v: Critique d’art.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2742f5a366c270c595e8ab74bd0a0454
https://doi.org/10.4000/critiquedart.29123