Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Laurence A, Brown"'
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The natural light environment is far more complex than that experienced by animals under laboratory conditions. As a burrowing species, wild mice are able to self-modulate their light exposure, a concept known as light environment
Externí odkaz:
https://doaj.org/article/56b81e92f772420ab3f60dd2bdbe42f3
Autor:
Sara Hestehave, Roxana Florea, Alexander J.H. Fedorec, Maria Jevic, Lucile Mercy, Annia Wright, Oakley B. Morgan, Laurence A. Brown, Stuart N. Peirson, Sandrine M. Géranton
Publikováno v:
PAIN Reports, Vol 9, Iss 6, p e1213 (2024)
Abstract. Introduction:. Chronic pain is a hallmark of joint diseases. Although these conditions are often accompanied by negative affective symptoms including depression and anxiety, these comorbidities are rarely studied simultaneously in preclinic
Externí odkaz:
https://doaj.org/article/6a22647df48c415095a43d7794cc57ec
Autor:
Gauri Ang, Laurence A. Brown, Shu K. E. Tam, Kay E. Davies, Russell G. Foster, Paul J. Harrison, Rolf Sprengel, Vladyslav V. Vyazovskiy, Peter L. Oliver, David M. Bannerman, Stuart N. Peirson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate th
Externí odkaz:
https://doaj.org/article/db96924aa90f4475ae84a2e870b1ccac
Autor:
Vasiliki Kiparoglou, Laurence A. Brown, Helen McShane, Keith M. Channon, Syed Ghulam Sarwar Shah
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background The evaluation of translational health research is important for various reasons such as the research impact assessment, research funding allocation, accountability, and strategic research policy formulation. The purpose of this s
Externí odkaz:
https://doaj.org/article/153486a6e78e410ca61de5cb8b5d29b8
Autor:
Jonathan N. King, Mike Martin, Valérie Chetboul, Luca Ferasin, Anne T. French, Günther Strehlau, Wolfgang Seewald, Sarah G. W. Smith, Simon T. Swift, Susan L. Roberts, Andrea M. Harvey, Christopher J. L. Little, Sarah M. A. Caney, Kerry E. Simpson, Andrew H. Sparkes, Eleanor J. Mardell, Eric Bomassi, Claude Muller, John P. Sauvage, Armelle Diquélou, Matthias A. Schneider, Laurence J. Brown, David D. Clarke, Jean‐Francois Rousselot
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 6, Pp 2559-2571 (2019)
Abstract Background Heart disease is an important cause of morbidity and mortality in cats, but there is limited evidence of the benefit of any medication. Hypothesis The angiotensin‐converting enzyme inhibitor benazepril would delay the time to tr
Externí odkaz:
https://doaj.org/article/e01e020d87f342d68c6287473d57527a
Autor:
Laurence A Brown, Stuart N Peirson
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
Transcriptomic experiments are often used in neuroscience to identify candidate genes of interest for further study. However, the lists of genes identified from comparable transcriptomic studies often show limited overlap. One approach to addressing
Externí odkaz:
https://doaj.org/article/890c196f38c6456fab64bc883a026ea0
Autor:
Angus S. Fisk, Shu K. E. Tam, Laurence A. Brown, Vladyslav V. Vyazovskiy, David M. Bannerman, Stuart N. Peirson
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Light exerts a wide range of effects on mammalian physiology and behavior. As well as synchronizing circadian rhythms to the external environment, light has been shown to modulate autonomic and neuroendocrine responses as well as regulating sleep and
Externí odkaz:
https://doaj.org/article/6c08c4d286a04b2c94adae5c054d27cf
Publikováno v:
Wellcome Open Research, Vol 1 (2017)
Background: Disruption of rhythms in activity and rest occur in many diseases, and provide an important indicator of healthy physiology and behaviour. However, outside the field of sleep and circadian rhythm research, these rhythmic processes are rar
Externí odkaz:
https://doaj.org/article/dd9b0349fad040008ee0e7f290da4558
Autor:
Vasiliki Kiparoglou, Keith M. Channon, Laurence A. Brown, Syed Ghulam Sarwar Shah, Helen McShane
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
BackgroundThe evaluation of translational health research is important for various reasons such as the research impact assessment, research funding allocation, accountability, and strategic research policy formulation. The purpose of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c115212b5700bbca59ede327348071ef
https://ora.ox.ac.uk/objects/uuid:3ea46a35-a60a-4169-9a14-71b7bbf81093
https://ora.ox.ac.uk/objects/uuid:3ea46a35-a60a-4169-9a14-71b7bbf81093
Publikováno v:
Biology, Vol 8, Iss 1, p 18 (2019)
Circadian rhythms are approximately 24 h cycles in physiology and behaviour that enable organisms to anticipate predictable rhythmic changes in their environment. These rhythms are a hallmark of normal healthy physiology, and disruption of circadian
Externí odkaz:
https://doaj.org/article/cafd174044b8446aa0b725b9b8d74c73