Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laurence Miguet"'
Publikováno v:
Journal of Computer-Aided Molecular Design. 20:67-81
Human 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) catalyzes the interconversion of cortisone into active cortisol. 11betaHSD1 inhibition is a tempting target for the treatment of a host of human disorders that might benefit from blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0d80440f81261ac64f18a5d760624d
https://doi.org/10.1007/s10822-006-9037-3
https://doi.org/10.1007/s10822-006-9037-3
Publikováno v:
Journal of Receptors and Signal Transduction. 26:611-630
Phenylthiocarbamide tastes intensely bitter to some individuals, but others find it completely tasteless. Recently, it was suggested that phenylthiocarbamide elicits bitter taste by interacting with a human G protein-coupled receptor (hTAS2R38) encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d3b33f4267d3edf949487506e01f4d
https://doi.org/10.1080/10799890600928210
https://doi.org/10.1080/10799890600928210
Autor:
F. A. Pasha, Thomas Gerards, Aline Thomas, André Luxen, Astrid Zervosen, Laurence Miguet, Martine Distèche-Nguyen
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (19), pp.5926-5936. ⟨10.1021/jm900625q⟩
Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (19), pp.5926-5936. ⟨10.1021/jm900625q⟩
Penicillin binding proteins (PBPs) are involved in the biosynthesis of the peptidoglycan layer constitutive of the bacterial envelope. They have been targeted for more than half a century by extensively derived molecular scaffolds of penicillins and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486186a694cf3b3cc4d383b323b67ee0
https://hal.archives-ouvertes.fr/hal-03068184
https://hal.archives-ouvertes.fr/hal-03068184
Publikováno v:
Journal of Cheminformatics, Vol 1, Iss 1, p 16 (2009)
Journal of Cheminformatics
Journal of Cheminformatics, Chemistry Central Ltd. and BioMed Central, 2009, pp.1-7
Journal of Cheminformatics
Journal of Cheminformatics, Chemistry Central Ltd. and BioMed Central, 2009, pp.1-7
Background Detailed experimental three dimensional structures of carbohydrates are often difficult to acquire. Molecular modelling and computational conformation prediction are therefore commonly used tools for three dimensional structure studies. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c72c0d74b74629f1724c504a35ce22
http://www.jcheminf.com/content/1/1/16
http://www.jcheminf.com/content/1/1/16
Autor:
Martine Rouvet, Denis Barron, Martin Michel, Laurence Miguet, Eric Hughes, Belén Sanchez, Britta Folmer, Olivier Heudi, Philippe Callier, Laurent Sagalowicz, Gary Williamson
Publikováno v:
Biochemical pharmacology. 78(12)
We have chemically synthesized two water-soluble forms of tocopherol succinate linked via an ester bond to hexaethylene glycol and dodecaethylene glycol. The self-assembly structure of the former in water is vesicular, whereas the latter forms elonga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d6bdb585d1eb017caf52c7b56f058e
https://pubmed.ncbi.nlm.nih.gov/19631613
https://pubmed.ncbi.nlm.nih.gov/19631613
Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2)
Autor:
Peter Krajcsi, M.-Belen Sanchez, Paul A. Kroon, Vanessa Crespy, Laurence Miguet, H. Glavinas, Isabelle Aeberli, Denis Barron, Gary Williamson, Ziding Zhang, Paul W. Needs, Martin Grigorov
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 35(8)
The exporter ABCC2 (cMOAT, MRP2) is a membrane-bound protein on the apical side of enterocytes and hepatic biliary vessels that transports leukotriene C(4), glutathione, some conjugated bile salts, drugs, xenobiotics, and phytonutrients. The latter c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ef8ad42fa2c24d2987fd525b4ff9c6
https://pubmed.ncbi.nlm.nih.gov/17478601
https://pubmed.ncbi.nlm.nih.gov/17478601
Autor:
Laurence Miguet, Astrid Zervosen, Thomas Gerards, Farhan A. Pasha, André Luxen, Martine Distèche-Nguyen, Aline Thomas
Publikováno v:
Journal of Medicinal Chemistry; Oct2009, Vol. 52 Issue 19, p5926-5936, 11p