Zobrazeno 1 - 10
of 393
pro vyhledávání: '"Laurence, de Leval"'
Autor:
Junji Koya, Tomohiko Tanigawa, Kota Mizuno, Haryoon Kim, Yuta Ito, Mitsuhiro Yuasa, Kentaro Yamaguchi, Yasunori Kogure, Yuki Saito, Sumito Shingaki, Mariko Tabata, Koichi Murakami, Kenichi Chiba, Ai Okada, Yuichi Shiraishi, Amira Marouf, Raphaël Liévin, Sammara Chaubard, Arnaud Jaccard, Olivier Hermine, Laurence de Leval, Olivier Tournilhac, Gandhi Damaj, Philippe Gaulard, Lucile Couronné, Teruhito Yasui, Kazutaka Nakashima, Hiroaki Miyoshi, Koichi Ohshima, Keisuke Kataoka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Extranodal NK/T-cell lymphoma (ENKTCL) is an Epstein-Barr virus (EBV)-related neoplasm preferentially involving the upper aerodigestive tract. Here we show that NK-cell-specific Trp53 disruption in mice leads to the development of NK-cell ly
Externí odkaz:
https://doaj.org/article/68fc246b7ff6480fbf1db57d7aa345f7
Autor:
Anja Fischer, Thomas K. Albert, Natalia Moreno, Marta Interlandi, Jana Mormann, Selina Glaser, Paurnima Patil, Flavia W. de Faria, Mathis Richter, Archana Verma, Sebastian T. Balbach, Rabea Wagener, Susanne Bens, Sonja Dahlum, Carolin Göbel, Daniel Münter, Clara Inserte, Monika Graf, Eva Kremer, Viktoria Melcher, Gioia Di Stefano, Raffaella Santi, Alexander Chan, Ahmet Dogan, Jonathan Bush, Martin Hasselblatt, Sylvia Cheng, Signe Spetalen, Alexander Fosså, Wolfgang Hartmann, Heidi Herbrüggen, Stella Robert, Florian Oyen, Martin Dugas, Carolin Walter, Sarah Sandmann, Julian Varghese, Claudia Rossig, Ulrich Schüller, Alexandar Tzankov, Martin B. Pedersen, Francesco A. d’Amore, Karin Mellgren, Udo Kontny, Venkatesh Kancherla, Luis Veloza, Edoardo Missiaglia, Virginie Fataccioli, Philippe Gaulard, Birgit Burkhardt, Oliver Soehnlein, Wolfram Klapper, Laurence de Leval, Reiner Siebert, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS SMARCB1- , which is characterized by the lack of the SMARCB1 protein and occurs
Externí odkaz:
https://doaj.org/article/f9838f5a5f15480799585f8fa2420a7e
Autor:
Ece Özoğul, Anna Montaner, Melina Pol, Gerard Frigola, Olga Balagué, Charlotte Syrykh, Pablo Bousquets-Muñoz, Romina Royo, Juliette Fontaine, Alexandra Traverse-Glehen, Marco M. Bühler, Luca Giudici, Marco Roncador, Thorsten Zenz, Sylvain Carras, Severine Valmary-Degano, Laurence de Leval, Jan Bosch-Schips, Fina Climent, Julia Salmeron-Villalobos, Melika Bashiri, Silvia Ruiz-Gaspà, Dolors Costa, Sílvia Beà, Itziar Salaverria, Eva Giné, Leticia Quintanilla-Martinez, Pierre Brousset, Mark Raffeld, Elaine S. Jaffe, Xose S. Puente, Cristina López, Ferran Nadeu, Elias Campo
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Mantle cell lymphoma (MCL) is genetically characterized by the IG::CCND1 translocation mediated by an aberrant V(D)J rearrangement. CCND1 translocations and overexpression have been identified in occasional aggressive B-cell lymphomas with u
Externí odkaz:
https://doaj.org/article/ebc32ff445d443efa40b812995ecadc9
Autor:
Valentin Loser, Amandine Segot, Laurence de Leval, Bettina Bisig, Jean-Philippe Brouland, Ekkehard Hewer, Carmen Barcena, Andreas F. Hottinger, Caroline Pot
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Diagnosis of primary diffuse large B-cell lymphoma of the central nervous system (PCNSL) is challenging and often delayed. MRI imaging, CSF cytology and flow cytometry have a low sensitivity and even brain biopsies can be misleadi
Externí odkaz:
https://doaj.org/article/cb82f128217a4b3c956f892a7ea4a192
Autor:
Gabriela Blanchard, MD, PhD, Bettina Bisig, MD, PhD, Laurence de Leval, MD, PhD, Daniel Hohl, MD, Emmanuella Guenova, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 48, Iss , Pp 98-102 (2024)
Externí odkaz:
https://doaj.org/article/7aa1559c0b7549b5a0454d4373fe319b
Autor:
Pierre Stephan, Jimmy Perrot, Allison Voisin, Maud Barbery, Thibault Andrieu, Maxime Grimont, Julie Caramel, Mathilde Bardou, Garance Tondeur, Edoardo Missiaglia, Philippe Gaulard, François Lemmonier, Laurence de Leval, Emmanuel Bachy, Pierre Sujobert, Laurent Genestier, Alexandra Traverse-Glehen, Yenkel Grinberg-Bleyer
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Whereas immunotherapies have revolutionized the treatment of different solid and hematological cancers, their efficacy in nodal peripheral T-cell lymphomas (PTCLs) is limited, due to a lack of understanding of the immune response they trigger. To ful
Externí odkaz:
https://doaj.org/article/07a54dde7d7a45488d6e41ed5e630c1d
Autor:
Marietta Straub, Alexandra Auderset, Laurence de Leval, Nathalie Piazzon, Damien Maison, Marie-Catherine Vozenin, Jonathan Ollivier, Benoît Petit, Daniel M. Sigman, Alfredo Martínez-García
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Studies have suggested that cancerous tissue has a lower 15N/14N ratio than benign tissue. However, human data have been inconclusive, possibly due to constraints on experimental design. Here, we used high-sensitivity nitrogen isotope method
Externí odkaz:
https://doaj.org/article/45e0609ba8cd4fee9c37ac26aa0acc34
Autor:
Kerry J. Savage, Laurence de Leval
Publikováno v:
Haematologica, Vol 109, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/12ab8f082c994018a84b982afa23b974
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Predominantly nodal is the most common clinical presentation of peripheral T- (and NK-) cell lymphomas (PTCL), which comprise three main groups of diseases: (i) systemic anaplastic large cell lymphomas (ALCL), whether positive or negative for anaplas
Externí odkaz:
https://doaj.org/article/f7aba068dd5b45fbb790493d3f34a0d1
Autor:
Kerry J. Savage, Laurence de Leval
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/49a4ce5b7fe74a7aa1b35d2e3b4f4f11