Zobrazeno 1 - 10
of 477
pro vyhledávání: '"Laurence, Huang"'
Autor:
Daniel G. Dunlap, Libing Yang, Shulin Qin, Kelvin Li, Adam Fitch, Laurence Huang, Bryan J. McVerry, Timothy W. Hand, Barbara A. Methé, Alison Morris
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background The advent of culture-independent, next-generation DNA sequencing has led to the discovery of distinct lung bacterial communities. Studies of lung microbiome taxonomy often reveal only subtle differences between health and disease
Externí odkaz:
https://doaj.org/article/35a0074d15624af692ef8314957d1bdc
Autor:
Katerina L Byanova, Jessica Fitzpatrick, Amanda K Jan, Maggie McGing, Marlena Hartman-Filson, Carly K Farr, Michelle Zhang, Kendall Gardner, Jake Branchini, Robert Kerruish, Sharvari Bhide, Aryana Bates, Jenny Hsieh, Rebecca Abelman, Peter W Hunt, Richard J Wang, Kristina A Crothers, Laurence Huang
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288803 (2023)
ObjectivesAn isolated reduction in the diffusing capacity for carbon monoxide (DLco; iso↓DLco) is one of the most common pulmonary function test (PFT) abnormalities in people living with HIV (PWH), but its clinical implications are incompletely und
Externí odkaz:
https://doaj.org/article/44cab78bc50a4c3d89755fb8929c67a5
Autor:
Abdulwahab Sessolo, Emmanuel Musisi, Sylvia Kaswabuli, Josephine Zawedde, Patrick Byanyima, Wilber Sabiiti, Stanley Walimbwa, Joseph Ola, Ingvar Sanyu, Rejani Lalitha, Moses Kamya, Lucian Davis, William Worodria, Laurence Huang
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284041 (2023)
BackgroundStool is a potential sample for diagnosing Mycobacterium tuberculosis (Mtb) in patients with difficulty in expectorating. However, high mycobacterial culture contamination rates and Xpert MTB/RIF Ultra test error rates on stool samples have
Externí odkaz:
https://doaj.org/article/e05f1f399cf34f5bbfe7bb1f77bd9f4e
Autor:
Patrick Byanyima, Sylvia Kaswabuli, Emmanuel Musisi, Catherine Nabakiibi, Josephine Zawedde, Ingvar Sanyu, Abdul Sessolo, Alfred Andama, William Worodria, Laurence Huang, J. Lucian Davis
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT The objective of this prospective observational study carried out at China-Uganda Friendship Hospital-Naguru in Kampala, Uganda, was to determine the performance of GeneXpert MTB/RIF Ultra (Xpert Ultra) molecular testing on saliva for active
Externí odkaz:
https://doaj.org/article/e91ecc43c5544f52a1c45c11dcd34562
Autor:
Sylvia Kaswabuli, Emmanuel Musisi, Patrick Byanyima, Abdul Sessolo, Ingvar Sanyu, Josephine Zawedde, William Worodria, Laurence Huang, Alfred Okeng, Freddie Bwanga
Publikováno v:
SAGE Open Medicine, Vol 10 (2022)
Objective: The objective of the study was to determine the diagnostic performance of the GenoQuick MTB test on heated sputum against the conventional Lowenstein–Jensen Mycobacterium tuberculosis culture as the reference method for tuberculosis diag
Externí odkaz:
https://doaj.org/article/d9fc2e3686924df8828066110a384dea
Autor:
Nicholas D. Walter, Sarah E. M. Born, Gregory T. Robertson, Matthew Reichlen, Christian Dide-Agossou, Victoria A. Ektnitphong, Karen Rossmassler, Michelle E. Ramey, Allison A. Bauman, Victor Ozols, Shelby C. Bearrows, Gary Schoolnik, Gregory Dolganov, Benjamin Garcia, Emmanuel Musisi, William Worodria, Laurence Huang, J. Lucian Davis, Nhung V. Nguyen, Hung V. Nguyen, Anh T. V. Nguyen, Ha Phan, Carol Wilusz, Brendan K. Podell, N’ Dira Sanoussi, Bouke C. de Jong, Corinne S. Merle, Dissou Affolabi, Helen McIlleron, Maria Garcia-Cremades, Ekaterina Maidji, Franceen Eshun-Wilson, Brandon Aguilar-Rodriguez, Dhuvarakesh Karthikeyan, Khisimuzi Mdluli, Cathy Bansbach, Anne J. Lenaerts, Radojka M. Savic, Payam Nahid, Joshua J. Vásquez, Martin I. Voskuil
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
It is unclear why different antibiotics vary in their ability to shorten treatment of tuberculosis. Here, the authors show that a measure based on ribosomal RNA synthesis in Mycobacterium tuberculosis correlates with treatment shortening in culture,
Externí odkaz:
https://doaj.org/article/e0c6c2c659ca434dbad834a1759cfbb7
Autor:
Sudha Bhadriraju, Douglas W. Fadrosh, Meera K. Shenoy, Din L. Lin, Kole V. Lynch, Kathryn McCauley, Rashida A. Ferrand, Edith D. Majonga, Grace McHugh, Laurence Huang, Susan V. Lynch, John Z. Metcalfe
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Chronic lung disease (CLD) is a common co-morbidity for HIV-positive children and adolescents on antiretroviral therapy (ART) in sub-Saharan Africa. In this population, distinct airway microbiota may differentially confer risk of CLD. In a c
Externí odkaz:
https://doaj.org/article/5c889e806c114c2e94ed9a46227d7dc5
Autor:
Maria C. Rodriguez-Barradas, Kathleen A. McGinnis, Kathleen Akgün, Janet P. Tate, Sheldon T. Brown, Adeel A. Butt, Michael Fine, Matthew Bidwell Goetz, Christopher J. Graber, Laurence Huang, David Rimland, Amy Justice, Kristina Crothers
Publikováno v:
Pneumonia, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background Cohort studies identifying the incidence, complications and co-morbidities associated with community acquired pneumonia (CAP) are largely based on administrative datasets and rely on International Classification of Diseases (ICD)
Externí odkaz:
https://doaj.org/article/6638d6f320aa443bac21d7085885ba31
Autor:
Wei Li, Fahim Syed, Richard Yu, Jing Yang, Ying Xia, Ryan F. Relich, Patrick M. Russell, Shanxiang Zhang, Mandana Khalili, Laurence Huang, Melissa A. Kacena, Xiaoqun Zheng, Qigui Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune checkpoints (ICPs) consist of paired receptor-ligand molecules that exert inhibitory or stimulatory effects on immune defense, surveillance, regulation, and self-tolerance. ICPs exist in both membrane and soluble forms in vivo and in vitro. Im
Externí odkaz:
https://doaj.org/article/3e293439aeab4c3c83cac3bdac7c8c37
Autor:
Emmanuel Musisi, Abdul Sessolo, Sylvia Kaswabuli, Josephine Zawedde, Patrick Byanyima, Shariifah Kasinga, Ingvar Sanyu, Esther Uwimaana, Stanley Walimbwa, Joseph Olore, Willy Ssengooba, Christine Sekaggya, Moses L. Joloba, William Worodria, Laurence Huang, Stephen H. Gillespie, Derek J. Sloan, Wilber Sabiiti
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Not all patients produce sputum, yet most available TB tests use sputum. We investigated the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load assay (TB-MBLA), for the detection and quantification of M
Externí odkaz:
https://doaj.org/article/1b34d326aad843688cace72aeab22c51