Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Laurence, Dunn"'
Autor:
Catherine Hanna, Sarah Jefferies, Marc Pittman, Kathreena M Kurian, Rebecca Sleigh, Karin Williams, Sara Erridge, Catherine McBain, Garth Cruickshank, Ross Carruthers, Colin Watts, Alan Jackson, Laurence Dunn, Lisa Godfrey, Karen Strathdee, Anthony J. Chalmers, Alex McCormick, Sarah Halford
Publikováno v:
Neuro Oncol
Background The poly(ADP-ribose) polymerase (PARP) inhibitor olaparib potentiated radiation and temozolomide (TMZ) chemotherapy in preclinical glioblastoma models but brain penetration was poor. Clinically, PARP inhibitors exacerbate the hematological
Autor:
Anand Dixit, Arshad Majid, Diederik Bulters, Nick S. Ward, Paul Stroemer, Kenneth Pollock, Laurence Dunn, Mark Willmot, John Sinden, Pippa J. Tyrrell, Philip M.W. Bath, Keith W. Muir, Nikola Sprigg, Julian Howell
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
BackgroundHuman neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line CTX0E03 in the subacute—chronic recovery phase of str
Autor:
John Laurence Dunn
Publikováno v:
Excursions Journal. 6:1-11
Occupying Space in American Literature and Culture seeks to furnish contemporary American with the conceptual spatial paradigms described by the great theorists of the social structures of the everyday, Henri Lefebvre and Michel De Certeau. It does t
Autor:
Deborah Houston, Naomi Fersht, Matthieu Resche-Rigon, Laurence Dunn, Charles Champeaux, Akbar Khan, Vincent Jecko, Lewis Thorne
Publikováno v:
Neurosurgery. 85:E461-E469
BACKGROUND In contrast to benign meningiomas, malignant meningiomas (MM) are rare and associated with an unfavourable prognosis. Reports on MM concern fairly small cohorts, often comprising less than 30 cases. OBJECTIVE To describe the outcome MM and
Publikováno v:
Neurochirurgie. 63:273-281
To analyse the outcome of patients with WHO grade II meningioma and identify factors that may influence recurrence and survival.Between January 2000 and October 2016, a retrospective search identified 215 WHO grade II meningiomas operated on at our i
Publikováno v:
Acta neurochirurgica.
Studies on meningioma are reported with inadequate allowance for competing causes of progression or death. The aim of this study was to describe the outcome of patients with intracranial WHO grade I meningioma and identify factors that may influence
Autor:
Philip M.W. Bath, John McLean, Keith W. Muir, Wilma Smith, Celestine Santosh, Alex McConnachie, Kenneth Pollock, Dheeraj Kalladka, Caroline Haig, Laurence Dunn, John Sinden
Publikováno v:
The Lancet. 388:787-796
Background:\ud \ud CTX0E03 is an immortalised human neural stem-cell line from which a drug product (CTX-DP) was developed for allogeneic therapy. Dose-dependent improvement in sensorimotor function in rats implanted with CTX-DP 4 weeks after middle
Autor:
Anthony J. Chalmers, Rebecca Sleigh, Sarah Jefferies, Marc Pittman, Catherine McBain, Christopher Herbert, Mark Webster-Smith, Garth Cruickshank, Laurence Dunn, Juanita Lopez, Sarah Halford, Lisa Godfrey, Sara Erridge, Colin Watts
2022Background: Olaparib, a small molecule inhibitor of poly (ADP-ribose) polymerase (PARP), may improve GBM outcomes by enhancing cytotoxic effects of ionising radiation and TMZ. Clinical development of PARP inhibitors has been restricted by exacerb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd36c3df22602ece5ea4f946cae5b16d
https://europepmc.org/articles/PMC5692745/
https://europepmc.org/articles/PMC5692745/
Publikováno v:
Journal of neuro-oncology. 134(2)
To describe the outcome of patients diagnosed with central nervous system haemangiopericytoma (HPC) or solitary fibrous tumour (SFT) and identify factors that may influence recurrence and survival. Between January 2000 and September 2016, a retrospec
Publikováno v:
Clinical Endocrinology. 75:673-677
Summary Background Higher field strength magnetic resonance imaging (MRI) is becoming increasingly available and offers improved image quality; however, the clinical usefulness of this technique for the demonstration of surgically treatable functiona