Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lauren de Haan"'
Autor:
Anastasia Audrey, Yannick P. Kok, Shibo Yu, Lauren de Haan, Bert van de Kooij, Nathalie van den Tempel, Mengting Chen, H. Rudolf de Boer, Bert van der Vegt, Marcel A.T.M. van Vugt
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114116- (2024)
Summary: Overexpression of Cyclin E1 perturbs DNA replication, resulting in DNA lesions and genomic instability. Consequently, Cyclin E1-overexpressing cancer cells increasingly rely on DNA repair, including RAD52-mediated break-induced replication d
Externí odkaz:
https://doaj.org/article/86d70d48e7bc40ab910f579a37c6c2d3
Publikováno v:
Biochemical Society transactions. 50(4)
Failure of cells to process toxic double-strand breaks (DSBs) constitutes a major intrinsic source of genome instability, a hallmark of cancer. In contrast with interphase of the cell cycle, canonical repair pathways in response to DSBs are inactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15592188a8d9ac88beb4ef206a5b5c8d
https://pubmed.ncbi.nlm.nih.gov/36040211
https://pubmed.ncbi.nlm.nih.gov/36040211
Autor:
Benjamin Vitre, Diana C.J. Spierings, Dong Hyun Kim, Bjorn Bakker, Lauren de Haan, Kathleen M. Fisch, René Wardenaar, Floris Foijer, Jon Artates, Andréa E. Tijhuis, Marcus Maldonado, Yin Wang, Ouyang Zhengyu, Don W. Cleveland, Matthew A. Demarest, Ofer Shoshani, Adam Mark, Roman Sasik
Publikováno v:
Genes Dev
Genes & Development, 35(15-16), 1093-1108. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Genes & Development, 35(15-16), 1093-1108. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Abnormal numerical and structural chromosome content is frequently found in human cancer. To test the role of aneuploidy in tumor initiation and progression, we generated mice with random aneuploidies by transient induction of polo-like kinase 4 (Plk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d26351348f42921270548637cb2e52a
https://hal.archives-ouvertes.fr/hal-03367172/document
https://hal.archives-ouvertes.fr/hal-03367172/document
