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pro vyhledávání: '"Lauren Wimer"'
Senescent cells (SnCs) are typically studied as endpoints of a complex transformational process, owing to their frequent maladaptive effects on surrounding tissue and cells. SnCs accumulate with age, and while they ultimately comprise a small percent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ec9631b630ac653104b012a302a642
https://doi.org/10.1101/2023.02.17.529001
https://doi.org/10.1101/2023.02.17.529001
Autor:
Lauren Wimer, Kiyomi R. Kaneshiro, Jessica Ramirez, Martin Valdearcos, Muniesh Shanmugam, Dominique Gaffney, Parminder Singh, Jennifer Beck, Durai Sellegounder, Soo-Jin Cho, John Newman, James Galligan, Suneil Koliwad, Pankaj Kapahi
Non-enzymatic reactions in glycolysis lead to the accumulation of methylglyoxal (MGO), a reactive precursor to advanced glycation end-products (AGEs), which has been suggested to drive obesity- and aging-associated pathologies. We observe that a comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6aed355a07bfcb828a0a667759fb83c
https://doi.org/10.1101/2022.08.10.503411
https://doi.org/10.1101/2022.08.10.503411
Autor:
Lauren Wimer, Martin Valdearcos Contreras, Muniesh Muthaiyan Shanmugam, Jessica Ramirez, Jennifer Beck, Suneil Koliwad, Pankaj Kapahi
Publikováno v:
Innovation in Aging. 5:681-681
Obesity remains one of the leading risk factors for aging and age-related diseases such as Alzheimer’s and type II diabetes, and effects 40% of the US population. The occurrence of obesity has been closely tied to an increase in sugar consumption w