Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren Verra"'
Autor:
Rebecca E Brown, Xiaofeng A Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H Freudenreich
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001940 (2022)
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://doaj.org/article/4e5e87cf75114ffc87feeec5e2eda3e1
Autor:
Lionel Gellon, David F Razidlo, Olive Gleeson, Lauren Verra, Danae Schulz, Robert S Lahue, Catherine H Freudenreich
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001298 (2011)
Expansion of DNA trinucleotide repeats causes at least 15 hereditary neurological diseases, and these repeats also undergo contraction and fragility. Current models to explain this genetic instability invoke erroneous DNA repair or aberrant replicati
Externí odkaz:
https://doaj.org/article/df62359b7a2d48c093fd41e76a685e52
Autor:
Rebecca E. Brown, Xiaofeng A. Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H. Freudenreich
Publikováno v:
PLoS biology. 20(12)
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afee7be703d25307eba247851977320
https://pubmed.ncbi.nlm.nih.gov/36574440
https://pubmed.ncbi.nlm.nih.gov/36574440
Autor:
Rebecca E. Brown, Xiaofeng A. Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H. Freudenreich
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4738473bce4129783170e65c1daafc6
https://doi.org/10.1101/2021.12.06.471001
https://doi.org/10.1101/2021.12.06.471001
Autor:
Ranjith P. Anand, Lauren Verra, Catherine H. Freudenreich, Laura Sloan, Jennifer Nguyen, Guy-Franck Richard, David Viterbo
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (8), pp.4519-4531. ⟨10.1093/nar/gkx088⟩
Nucleic Acids Research, 2017, 45 (8), pp.4519-4531. ⟨10.1093/nar/gkx088⟩
Nucleic Acids Research, Oxford University Press, 2017, 45 (8), pp.4519-4531. ⟨10.1093/nar/gkx088⟩
Nucleic Acids Research, 2017, 45 (8), pp.4519-4531. ⟨10.1093/nar/gkx088⟩
International audience; Trinucleotide repeats are a source of genome instability , causing replication fork stalling, chromosome fragility, and impaired repair. Specialized heli-cases play an important role in unwinding DNA structures to maintain gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee53dcf9d5f0c4d2e8f9128e47c16cb4
https://hal.sorbonne-universite.fr/hal-01526732
https://hal.sorbonne-universite.fr/hal-01526732
Autor:
Danae Schulz, Robert S. Lahue, Catherine H. Freudenreich, Lionel Gellon, Lauren Verra, David F. Razidlo, Olive Gleeson
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001298 (2011)
PLoS Genetics
PLoS Genetics
Expansion of DNA trinucleotide repeats causes at least 15 hereditary neurological diseases, and these repeats also undergo contraction and fragility. Current models to explain this genetic instability invoke erroneous DNA repair or aberrant replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5946026ed0ce8da8a90eb562592e8e98
http://europepmc.org/articles/PMC3037408?pdf=render
http://europepmc.org/articles/PMC3037408?pdf=render