Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren T, Callaghan"'
Autor:
Mohamed F. Mohamed, Kajal Gupta, Josef W. Goldufsky, Ruchi Roy, Lauren T. Callaghan, Dawn M. Wetzel, Timothy M. Kuzel, Jochen Reiser, Sasha H. Shafikhani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Pseudomonas aeruginosa secretes the toxin ExoT, which is important for pathogenesis. Here, the authors show that ExoT inhibits NLRC4-dependent inflammatory responses during wound infection.
Externí odkaz:
https://doaj.org/article/2342fcd19c9a489d89c6717fe4338e53
Autor:
Lauren T. Callaghan, Anthea Lafreniere, Ekene A. Onwuka, Ross M. Beckman, Jennifer H. Foster, Norma Quintanilla, Charleta Guillory, Timothy C. Lee, Lily S. Cheng
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Spontaneous intestinal perforations in the neonatal population are mostly associated with low birth weight, prematurity, and necrotizing enterocolitis. Spontaneous intestinal perforation in the absence of these risk factors is extremely rare and shou
Externí odkaz:
https://doaj.org/article/d89a6a1e706845639df224cd05f181f3
Autor:
Sneha Ray, Margaret A. Phillips, Prema L. Mallipeddi, Myles W Smith, Zhen Zhang, Leah Imlay, Lauren T Callaghan, Dawn M. Wetzel, Hanspeter Niederstrasser, Bruce A. Posner
Publikováno v:
Chemical Science
The spiroindimicins are a unique class of chlorinated indole alkaloids characterized by three heteroaromatic rings structured around a congested spirocyclic stereocenter. Here, we report the first total synthesis of (+)-spiroindimicin A, which bears
Autor:
Mohamed F, Mohamed, Kajal, Gupta, Josef W, Goldufsky, Ruchi, Roy, Lauren T, Callaghan, Dawn M, Wetzel, Timothy M, Kuzel, Jochen, Reiser, Sasha H, Shafikhani
Publikováno v:
Nature communications. 13(1)
Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including Pseudomonas aeruginosa. Exotoxin T (ExoT) is the only T3SS effector protein
Autor:
Yueyang Huang, Christopher D. Rae, Shauna M. McGillivray, R. Samuel Baugh, Lauren T. Callaghan, Kenneth C. Keiler, John N. Alumasa
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Staphylococcus aureus is a leading cause of infection in the United States, and due to the rapid development of resistance, new antibiotics are constantly needed. trans-Translation is a particularly promising antibiotic target because it is conserved
Autor:
Yueyang, Huang, John N, Alumasa, Lauren T, Callaghan, R Samuel, Baugh, Christopher D, Rae, Kenneth C, Keiler, Shauna M, McGillivray
Publikováno v:
Antimicrobial agents and chemotherapy. 63(4)
Staphylococcus aureus is a leading cause of infection in the United States, and due to the rapid development of resistance, new antibiotics are constantly needed. trans-Translation is a particularly promising antibiotic target because it is conserved