Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lauren Sahakian"'
Autor:
Cara A. Timpani, Stephanie Kourakis, Danielle A. Debruin, Dean G. Campelj, Nancy Pompeani, Narges Dargahi, Angelo P. Bautista, Ryan M. Bagaric, Elya J. Ritenis, Lauren Sahakian, Didier Debrincat, Nicole Stupka, Patricia Hafner, Peter G. Arthur, Jessica R. Terrill, Vasso Apostolopoulos, Judy B. de Haan, Nuri Guven, Dirk Fischer, Emma Rybalka
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
New medicines are urgently required to treat the fatal neuromuscular disease Duchenne muscular dystrophy (DMD). Dimethyl fumarate (DMF) is a potent immunomodulatory small molecule nuclear erythroid 2-related factor 2 activator with current clinical u
Externí odkaz:
https://doaj.org/article/2f67a5d7f78e4aa7850dc5cf476bf2a1
Autor:
Lauren Sahakian, Ainsley M. Robinson, Linda Sahakian, Rhian Stavely, Mark R. Kelley, Kulmira Nurgali
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1569 (2023)
Inflammatory bowel disease (IBD) is characterized by chronic relapsing inflammation of the gastrointestinal tract. The prevalence of IBD is increasing with approximately 4.9 million cases reported worldwide. Current therapies are limited due to the s
Externí odkaz:
https://doaj.org/article/b49e1c34511948dba3e82acaf60a9d05
Autor:
Rhian Stavely, Lauren Sahakian, Rhiannon T. Filippone, Vanesa Stojanovska, Joel C. Bornstein, Samy Sakkal, Kulmira Nurgali
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1831 (2022)
High-mobility group box 1 (HMGB1) is a damage-associated molecular pattern released by dying cells to stimulate the immune response. During cell death, HMGB1 is translocated from the nucleus to the cytoplasm and passively released. High levels of sec
Externí odkaz:
https://doaj.org/article/70cf50452d6f465686deeaf42b08e7f2
Autor:
Lauren, Sahakian, Rachel, McQuade, Rhian, Stavely, Ainsley, Robinson, Rhiannon T, Filippone, Majid, Hassanzadeganroudsari, Raj, Eri, Raquel, Abalo, Joel C, Bornstein, Mark R, Kelley, Kulmira, Nurgali
Publikováno v:
Advances in experimental medicine and biology. 1383
Enteric neuropathy underlies long-term gastrointestinal (GI) dysfunction associated with several pathological conditions. Our previous studies have demonstrated that structural and functional changes in the enteric nervous system (ENS) result in pers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a4cb1d0739d1c39da7ac6c916d21611
https://pubmed.ncbi.nlm.nih.gov/36587161
https://pubmed.ncbi.nlm.nih.gov/36587161
Autor:
Cara A. Timpani, Stephanie Kourakis, Danielle A. Debruin, Dean G. Campelj, Nancy Pompeani, Narges Dargahi, Angelo P. Bautista, Ryan M. Bagaric, Elya J. Ritenis, Lauren Sahakian, Patricia Hafner, Peter G. Arthur, Jessica R. Terrill, Vasso Apostolopoulos, Judy B. de Haan, Nuri Guven, Dirk Fischer, Emma Rybalka
New medicines are urgently required to treat the fatal neuromuscular disease, Duchenne muscular dystrophy (DMD). DMD involves progressive muscle damage and weakness, which are preceded by oxidative stress, inflammation, and mitochondrial dysfunction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d6520d99980bdf3aa1539b4cbf92e6
https://doi.org/10.1101/2022.09.15.508124
https://doi.org/10.1101/2022.09.15.508124
Autor:
Rachel M. McQuade, Methma Bandara, Shanti Diwakarla, Lauren Sahakian, Myat Noe Han, Maryam Al Thaalibi, Madeleine R. Di Natale, Marsha Tan, Kiera H. Harwood, Elena K. Schneider-Futschik, Andrew Jarnicki
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
Background Respiratory inflammation is the body’s response to lung infection, trauma or hypersensitivity and is often accompanied by comorbidities, including gastrointestinal (GI) symptoms. Why respiratory inflammation is accompanied by GI dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9839fc95f2d42b239fabafd504f667cd
https://pubmed.ncbi.nlm.nih.gov/36322182
https://pubmed.ncbi.nlm.nih.gov/36322182
Autor:
Lauren Sahakian, Rachel McQuade, Rhian Stavely, Ainsley Robinson, Rhiannon T. Filippone, Majid Hassanzadeganroudsari, Raj Eri, Raquel Abalo, Joel C. Bornstein, Mark R. Kelley, Kulmira Nurgali
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031058424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cefc36ab1717e29eeaf2c5ac7ebbc4b5
https://doi.org/10.1007/978-3-031-05843-1_21
https://doi.org/10.1007/978-3-031-05843-1_21
Autor:
Rhian Stavely, Ahmed A Rahman, Lauren Sahakian, Monica D Prakash, Ainsley M Robinson, Majid Hassanzadeganroudsari, Rhiannon T Filippone, Sarah Fraser, Rajaraman Eri, Joel C Bornstein, Vasso Apostolopoulos, Kulmira Nurgali
Publikováno v:
Inflammatory bowel diseases. 28(8)
Background The autonomic nervous system (ANS) is thought to play a critical role in the anti-inflammatory reflex pathway in acute colitis via its interaction with the spleen and colon. Inflammation in the intestine is associated with a blunting of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456a7f502af1db4686dac0d51a2f8e65
https://pubmed.ncbi.nlm.nih.gov/35380670
https://pubmed.ncbi.nlm.nih.gov/35380670
Publikováno v:
Inflammatory Bowel Diseases. 25:1140-1151
Clinical investigations in inflammatory bowel disease (IBD) patients have provided increasing evidence that eosinophils contribute to chronic intestinal inflammation. Accumulation of eosinophils in the gastrointestinal tract correlates with the varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a854c2863d6d1cd56a76d16e21c3aad
https://doi.org/10.1093/ibd/izz024
https://doi.org/10.1093/ibd/izz024
Autor:
Lauren Sahakian, Mark R. Kelley, Rajaraman Eri, Ainsley M Robinson, Rhian Stavely, Rhiannon Filippone, Joel C. Bornstein, Xu Sean Yan, Kulmira Nurgali, Raquel Abalo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Inflamm Bowel Dis
instname
Inflamm Bowel Dis
Background: Inflammatory bowel disease (IBD) associates with damage to the enteric nervous system (ENS), leading to gastrointestinal (GI) dysfunction. Oxidative stress is important for the pathophysiology of inflammation-induced enteric neuropathy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724083d3a7c399a783c2dcf487417d04
http://hdl.handle.net/10261/261275
http://hdl.handle.net/10261/261275