Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lauren S. Sefcik"'
Autor:
Rachel E Young, Jodi Graf, Isabella Miserocchi, Ryan M Van Horn, Melissa B Gordon, Christopher R Anderson, Lauren S Sefcik
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219254 (2019)
Thermoresponsive polymers, such as poly(N-isopropyl acrylamide) (PNIPAM), have been identified and used as cell culture substrates, taking advantage of the polymer's lower critical solution temperature (LCST) to mechanically harvest cells. This techn
Externí odkaz:
https://doaj.org/article/5ac2b5e216a542cdada869643b91885b
Autor:
Lauren S. Sefcik, Katarina M. DiLillo, James K. Ferri, Christopher R. Anderson, Erik Wischerhoff, Filippo Gambinossi, André Laschewsky
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:2416-2428
Thermoresponsive polymer (TRP) cell culture substrates are widely utilized for nonenzymatic, temperature-triggered release of adherent cells. Increasingly, multicomponent TRPs are being developed to facilitate refined control of cell adhesion and det
Publikováno v:
ACS Applied Materials & Interfaces. 7:2518-2528
Adhesion control in liquid-liquid-solid systems represents a challenge for applications ranging from self-cleaning to biocompatibility of engineered materials. By using responsive polymer chemistry and molecular self-assembly, adhesion at solid/liqui
Autor:
Lauren S. Sefcik, Ashley Kaminski, Kevin Ling, André Laschewsky, Jean-François Lutz, Erik Wischerhoff
Publikováno v:
Cellular and Molecular Bioengineering. 6:287-298
The use of thermoresponsive polymer (TRP) substrates, such as PNIPAM, has become a valuable tool for the gentle detachment of cells from their culture surface while retaining cell–cell and cell–matrix contacts. P(MEO2MA-co-OEGMA) substrates (PMO)
Autor:
Kevin R. Lynch, Anthony O. Awojoodu, Feilim Mac Gabhann, Timothy L. Macdonald, Shayn M. Peirce, Edward A. Botchwey, Caren E. Petrie Aronin, Brian R. Wamhoff, Soo J. Shin, Lauren S. Sefcik
Publikováno v:
Tissue Engineering Part A. 17:617-629
Proper spatial and temporal regulation of microvascular remodeling is critical to the formation of functional vascular networks, spanning the various arterial, venous, capillary, and collateral vessel systems. Recently, our group has demonstrated tha
Autor:
Samuel G. McClugage, Rebekah A. Neal, Edward A. Botchwey, Lauren S. Sefcik, Roy C. Ogle, Mia C. Link
Publikováno v:
Tissue Engineering Part C: Methods. 15:11-21
The basement membrane protein, laminin I, has been used broadly as a planar two-dimensional film or in a three-dimensional form as a reconstituted basement membrane gel such as Matrigel to support cellular attachment, growth, and differentiation in v
Autor:
Caren E. Petrie Aronin, Meghan M. Nickerson, Edward A. Botchwey, Richard J. Price, Mikell Paige, Kristen A. Wieghaus, Lauren S. Sefcik, Milton L. Brown
Publikováno v:
Biomaterials. 29:4698-4708
Phthalimide neovascular factor (PNF1, formerly SC-3-149) is a potent stimulator of proangiogenic signaling pathways in endothelial cells. In this study, we evaluated the in vivo effects of sustained PNF1 release to promote ingrowth and expansion of m
Autor:
Rebekah A. Neal, Roy C. Ogle, Adam J. Katz, Anna M. Parker, Stephanie N. Kaszuba, Lauren S. Sefcik, Edward A. Botchwey
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 2:210-220
Electrospinning has recently gained widespread attention as a process capable of producing nanoscale fibres that mimic native extracellular matrix. In this study, we compared the osteogenic differentiation behaviour of human adipose stem cells (ASCs)
Autor:
Shayn Peirce-Cottler, Kevin R. Lynch, Nathan F. Chiappa, Lauren S. Sefcik, Edward A. Botchwey, Anthony O. Awojoodu, Molly E. Ogle
Biomaterial-mediated controlled release of soluble signaling molecules is a tissue engineering approach to spatially control processes of inflammation, microvascular remodeling, and host cell recruitment and to generate biochemical gradients in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5948906eb02caad6ecd4272520b86e
https://europepmc.org/articles/PMC4529737/
https://europepmc.org/articles/PMC4529737/
Autor:
Kyle S. Martin, Kenneth L. Brayman, Anthony O. Awojoodu, Shayn Peirce-Cottler, Lauren S. Sefcik, Edward A. Botchwey, Kevin R. Lynch, Daniel T. Bowers, Molly E. Ogle
Endothelial cells play significant roles in conditioning tissues after injury by the production and secretion of angiocrine factors. At least two distinct subsets of monocytes, CD45 + CD11b + Gr1 + Ly6C + inflammatory and CD45 + CD11b + Gr1 − Ly6C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b9629c9ece7bc0b693c650c095f7e2
https://europepmc.org/articles/PMC3752259/
https://europepmc.org/articles/PMC3752259/